Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 7, 2026, 4:18 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2449–2472 of 3,107 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Treatment of depression Clear all

Conditions: Mild Cognitive Impairment (MCI), Depression
Interventions: Escitalopram, Memantine, Placebo; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 60 Years and older
Enrollment: 115 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Borderline Personality Disorder
Interventions: Psychoeducational Videos, Neuropsychological Feedback, Non-BPD-related Educational Videos; Other
Lead sponsor: Mclean Hospital; Other
Eligibility: 18 Years and older
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Bipolar Disorder
Interventions: Quetiapine Fumarate; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 530 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 36
States / cities: Birmingham, Alabama • Scottsdale, Arizona • Cerritos, California + 33 more

Conditions: Depression
Interventions: Acupuncture; Procedure
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Stress
Interventions: Cognitive-Behavioral Group Therapy; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 16 Years and older · Female only
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Treatment Resistant Depression (TRD), Late Life Depression (LLD), Depression / Major Depressive Disorder
Interventions: Lumateperone, Placebo; Drug
Lead sponsor: Eric Lenze; Other
Eligibility: 60 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: Tucson, Arizona • St Louis, Missouri

Conditions: Hematopoietic/Lymphoid Cancer
Interventions: Paced respiration as part of PEPRR, PEPRR; Device · Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 298 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2013
U.S. locations: 2
States / cities: Aurora, Colorado • Denver, Colorado

Conditions: Major Depressive Disorder
Interventions: Psilocybin, Pimavanserin, Placebo; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 21 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression, Coronary Disease
Interventions: Cognitive behavior therapy, Supportive Stress Management; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 21 Years and older
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2006
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Maternal Perinatal Depression
Interventions: African-American Social Support Effectiveness Treatment-Partners alleviating Perinatal Depression (ASSET-PPD); Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Major Depression, Sleep
Interventions: TMS; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Stanford, California

Conditions: Depressive Symptoms
Interventions: Interpersonal Psychotherapy - Adolescent Skills Training, Services as usual; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 14 Years to 75 Years
Enrollment: 242 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Depression
Interventions: Buprenorphine; Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 50 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Lactation, Mindfulness, NICU, Breastmilk, Neonatal, Meditation, Pumping, Breast, Cortisol, Oxytocin, Anxiety, Depression
Interventions: Standard of Care, Mindfulness-based Intervention; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 20 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Psychotic Disorders, Prodromal Symptoms, Prodromal Schizophrenia, Psychosis, Family
Interventions: Family Focused Therapy for Clinical High Risk Youth (FFT-CHR), Enhanced Care (EC); Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 13 Years to 25 Years
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 6
States / cities: Los Angeles, California • San Diego, California • San Francisco, California + 3 more

Conditions: Bipolar II Disorder
Interventions: Interpersonal and Social Rhythm Therapy (IPSRT-BPII), Seroquel; Behavioral · Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 65 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Depression, Anxiety, Stress
Interventions: Space from Depression, Space from Anxiety, Space from Stress; Other
Lead sponsor: Silver Cloud Health; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Inflammatory Bowel Disease
Interventions: Integrated Brief Behavior Therapy (IBBT) Intervention, Treatment as usual; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 12 Years to 21 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Group Meetings
Interventions: TIPSTART; Behavioral
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 18 Years to 34 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Urbana, Illinois

Conditions: Postpartum Depression, Perinatal Depression
Interventions: Maternal Mental Health Access for Postpartum Depression- Prevention and UPLIFT- intervention, On-Demand + Discussion board (DB), Arm 2, On Demand (OD) + Video Conference (VC), Arm 3; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older · Female only
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Treatment Resistant Depressive Disorder
Interventions: Ketamine, Midazolam; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 55 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Severe Postpartum Depression
Interventions: SAGE-547, Placebo; Drug
Lead sponsor: Supernus Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 4
States / cities: Atlanta, Georgia • Worcester, Massachusetts • Chapel Hill, North Carolina + 1 more

Conditions: Breast Cancer, BRCA1 Mutation, BRCA2 Mutation
Interventions: Psychosocial variables; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Type 2 Diabetes, Depression, Insulin Resistance, Obesity, Adolescent Development
Interventions: Mindfulness-Based Intervention, Cognitive-Behavioral Therapy, Health Education; Behavioral
Lead sponsor: Colorado State University; Other
Eligibility: 12 Years to 17 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 4
States / cities: Aurora, Colorado • Fort Collins, Colorado • Washington D.C., District of Columbia + 1 more

Search by objective public record fields.

Brain Aging and Treatment Response in Geriatric Depression

Psychoeducational Videos and Digital Assessments for BPD

Controlled Study of the Use of Quetiapine Fumarate in the Treatment of Patients With Bipolar Depression

Effectiveness of Acupuncture for Depressed Patients Not Taking Antidepressant Medications

New Haven MOMS Partnership

Lumateperone for Late-Life Depression

Stress Management Intervention for Caregivers of Patients Undergoing Bone Marrow Transplant (BMT)

Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder

Treatment of Depression After Coronary Bypass Surgery

African-American Social Support Effectiveness Treatment

Sleep TMS for Depression

School Adolescent Mood Project: Efficacy of IPT-AST in Schools

Buprenorphine for Late-Life Treatment Resistant Depression

Mindfulness and Meditation Based Lactation Education on Maternal Breastmilk in the Neonatal ICU

Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy Trial

Psychotherapy for Bipolar II Depression, Pilot Study, Phase II

Effectiveness and Acceptability of Internet-delivered Treatment for Depression, Anxiety and Stress

Integrated Behavioral Health Innovations in Childhood Chronic Illness Care Delivery Systems

Feasibility of Therapy Integrating Peer-sharing, Technology, Aerobic and Resistance Training (TIPSTART)

Maternal Mental Health Access - MaMa

Ketamine for Treatment Resistant Late-Life Depression

A Study to Evaluate SAGE-547 in Participants With Severe Postpartum Depression

Depression and Body Image Distress Following Mastectomy With Reconstruction

Mindfulness-Based Intervention for Depression and Insulin Resistance in Adolescents