Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 10:18 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2521–2544 of 3,107 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Treatment of depression Clear all

Conditions: Depression
Interventions: Omega-3 Supplementation, Psychoeducational Psychotherapy (PEP), Placebo; Drug · Behavioral · Other
Lead sponsor: L. Eugene Arnold; Other
Eligibility: 7 Years to 14 Years
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Major Depressive Disorder
Interventions: Video Task, Imaginal Task; Behavioral · Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 3
States / cities: Atlanta, Georgia

Conditions: Depression, Pregnancy Related, Antenatal Depression
Interventions: Digital Delivery of Mindfulness-Based Cognitive Therapy; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 2
States / cities: Boulder, Colorado • Boston, Massachusetts

Conditions: Depressive Disorder
Interventions: Interpersonal Psychotherapy for Depressed Adolescents, Selective Serotonin Reuptake Inhibitor, Usual Care; Behavioral · Drug · Other
Lead sponsor: University of Minnesota; Other
Eligibility: 12 Years to 18 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Major Depressive Disorder
Interventions: Mecta Spectrum 5000Q paired with Soterix Medical 4X1 HD - ECT Multi-Channel Stimulation Interface; Device
Lead sponsor: University of New Mexico; Other
Eligibility: 50 Years to 80 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Depression
Interventions: Paroxetine, Bupropion; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2013
U.S. locations: 1
States / cities: New York, New York

Conditions: Suicidal and Self-injurious Behaviour
Interventions: Dialectical Behavior Therapy, Individual and Group Supportive Therapy; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 13 Years to 17 Years
Enrollment: 173 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Treatment-resistant Depression
Interventions: ketamine, midazolam; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Depression, Cancer, Adolescent, Young Adult, Adult
Interventions: AYA Survivors Coping and Emotional Needs Toolkit (ASCENT); Behavioral
Lead sponsor: East Carolina University; Other
Eligibility: 15 Years to 39 Years
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Greenville, North Carolina • Winston-Salem, North Carolina

Conditions: Depression, Spinal Cord Injuries
Interventions: Acceptance and commitment therapy (ACT), Wait-list control group with psychoeducation materials provided; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Cigarette Smoking, Drug Use
Interventions: Standard Treatment, BAD-AS, Transdermal Nicotine Patch; Behavioral · Drug
Lead sponsor: University of Maryland, College Park; Other
Eligibility: 18 Years to 65 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Integrating Behavioral Health
Interventions: Software; Other
Lead sponsor: Medical Decision Logic, Inc.; Industry
Eligibility: Not listed
Enrollment: 16,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Connersville, Indiana • Philadelphia, Pennsylvania

Conditions: Insomnia, Primary, Major Depressive Disorder, Rumination
Interventions: digital Cognitive Behavioral Therapy for Insomnia, face-to-face Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene Education Control; Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older
Enrollment: 1,237 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Novi, Michigan

Conditions: Major Depressive Disorder
Interventions: repetitive Transcranial Magnetic Stimulation; Device
Lead sponsor: Neuronetics; Other
Eligibility: 22 Years to 70 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Depressive Disorder, Major
Interventions: LY2216684 (edivoxetine), SSRI; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years and older
Enrollment: 608 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 24
States / cities: Birmingham, Alabama • Little Rock, Arkansas • Cerritos, California + 21 more

Conditions: Major Depressive Disorder
Interventions: LY03005, Pristiq; Drug
Lead sponsor: Luye Pharma Group Ltd.; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Eatontown, New Jersey

Conditions: Opioid-use Disorder, Stress Related Disorder, Anxiety, Pain Interference
Interventions: Live-Online M-ROCC, Live-Online Control; Behavioral
Lead sponsor: Cambridge Health Alliance; Other
Eligibility: 18 Years to 70 Years
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Somerville, Massachusetts

Conditions: Major Depressive Disorder
Interventions: ActiveCBT, CalmCBT; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Ames, Iowa

Conditions: Depression, Chronic Disease, Hispanic Americans
Interventions: Self-management group, Enhanced usual care; Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: COVID-19 Pandemic, Health Knowledge, Attitudes, Practice, Perinatal Depression, Mental Health Wellness, Post Partum Depression
Interventions: Baby2Home Mobile Application; Other
Lead sponsor: Women and Infants Hospital of Rhode Island; Other
Eligibility: 18 Years and older
Enrollment: 642 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 2
States / cities: Chicago, Illinois • Providence, Rhode Island

Conditions: Depression
Interventions: MedLink System; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Depression
Interventions: Transcranial Magnetic Simulation, Mixed reality neuronavigation; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Stanford, California

Conditions: Depression, Mood Disorders, Depressive Disorder
Interventions: Citalopram; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Stanford, California

Conditions: Major Depression
Interventions: Sertraline, Hypericum perforatum (St. John's wort); Drug
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2001
U.S. locations: 12
States / cities: San Diego, California • Stanford, California • Torrance, California + 9 more

Search by objective public record fields.

Omega-3 and Therapy Study for Depression

Heart Rate Variability in Depression

Preventing Depressive Relapse in Pregnant Women With Recurrent Depression

An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression

Electroconvulsive Therapy Amplitude Titration

Paroxetine/Bupropion in Suicide Attempters/Ideators With Major Depression

Collaborative Adolescent Research on Emotions and Suicide

Efficacy of Repeated Ketamine Infusions for Treatment-resistant Depression

Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit

Acceptance and Commitment Therapy for Depressed Individuals Living With Spinal Cord Injury Sustained Within 5 Years

Behavioral Intervention for Low Income Depressed Smokers in Drug Treatment

Web Platform to Integrate Behavioral Health

Sleep To Reduce Incident Depression Effectively

Study to Evaluate Treatment Effects Associated With the NeuroStar SoftStart Treatment Feature

A Safety Study in Participants With Major Depressive Disorder

Relative Bioavailability (RBA) Study of LY03005 vs Pristiq®

Effect of Mindfulness on Opioid Use and Anxiety During Primary Care Buprenorphine Treatment (R33 Phase)

CBT+ for Depression

Group Self-Management of Depression and Medical Illness

Baby2Home (B2H) Mobile Health Application

Mobile Technology to Engage and Link Patients and Providers in Antidepressant Treatment

Comparison of Targeting Methods for Transcranial Magnetic Stimulation Treatment of Depression

Functional MRI Before and After Treatment for Depression

Treatment of Major Depression With St. John's Wort (Hypericum)