Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 12:16 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2569–2592 of 3,107 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Treatment of depression Clear all

Conditions: Pregnancy, Depression, Postpartum Depression
Interventions: MBCT-PD; Behavioral
Lead sponsor: University of Colorado, Boulder; Other
Eligibility: 18 Years and older · Female only
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 4
States / cities: Boulder, Colorado • Denver, Colorado • Atlanta, Georgia

Conditions: Depression, Depressive Disorder, Depressive Disorder, Major
Interventions: Buprenorphine, Placebo; Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 21 Years and older
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Depression, Anxiety, Disruptive Behavior Disorder, Trauma, Psychological
Interventions: Enhanced version of Interconnected Systems Framework, Positive Behavioral Interventions and Supports with Co-located School Mental Health; Behavioral
Lead sponsor: East Carolina University; Other
Eligibility: Not listed
Enrollment: 1,208 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 2
States / cities: Greenville, North Carolina • Columbia, South Carolina

Conditions: Bipolar Depression, Treatment Effectiveness, Measure-based Guidance
Interventions: Extended release oxcarbazepine vs Immediate release oxcarbazepine; Drug
Lead sponsor: Collaborative Care Initiative, LLC; Other
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Stress Disorders, Post-Traumatic
Interventions: Trauma-Focused Cognitive Behavioral Therapy, Sertraline Pill, Placebo Oral Tablet; Behavioral · Drug
Lead sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute); Other
Eligibility: 10 Years to 17 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2006
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Traumatic Brain Injury, Concussion, Mild, Depressive Symptoms
Interventions: Active: rTMS, Sham: rTMS; Device
Lead sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine; Other
Eligibility: 18 Years to 64 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Bethesda, Maryland • Fort Belvoir, Virginia

Conditions: Major Depressive Disorder
Interventions: Stimulation-ON, Stimulation-OFF, Stimulation-ON Active Control; Device
Lead sponsor: Andrew Krystal; Other
Eligibility: 22 Years to 70 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2035
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Parkinson's Disease, Depression
Interventions: Cognitive Behavior Therapy (CBT), Treatment As Usual (TAU); Other
Lead sponsor: Yale University; Other
Eligibility: 40 Years to 80 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Depression, Type 1 Diabetes
Interventions: Cognitive behavioral therapy for adherence and depression; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Anxiety, Depression
Interventions: Acceptance-Based Behavior Therapy (ABBT), Treatment-as-Usual (TAU); Behavioral · Other
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Depression, Anxiety
Interventions: Supporting Our Valued Adolescents (SOVA), Enhanced Usual Care; Behavioral · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 12 Years to 19 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Treatment Resistant Depression, Refractory Depression, Therapy-Resistant Depression, Late Life Depression, Geriatric Depression
Interventions: Ketamine; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 65 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 4
States / cities: Los Angeles, California • St Louis, Missouri • New York, New York + 1 more

Conditions: Depression
Interventions: W-GenZD Mobile Application, Digital Education Application (W-EdZD); Device
Lead sponsor: Woebot Health; Industry
Eligibility: 13 Years to 17 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Head and Neck Cancer
Interventions: Guided Imagery, Treatment as Usual; Behavioral · Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 100 Years
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Social Anxiety
Interventions: Internet-delivered self-help for social anxiety based on principles of cognitive behavioral therapy; Behavioral
Lead sponsor: Trustees of Princeton University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Princeton, New Jersey

Conditions: Depression
Interventions: Parent Skills Training, Protecting Families Program (PFP); Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 9 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Major Depressive Disorder
Interventions: LY03005; Drug
Lead sponsor: Luye Pharma Group Ltd.; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Major Depressive Disorder
Interventions: Mindfulness Based Cognitive Therapy, Health Enhancement Program and medication management; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 173 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Major Depressive Disorder
Interventions: Brief Behavioral Activation Treatment for Depression; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 21 Years to 55 Years
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Major Depressive Disorder
Interventions: Psilocybin, Cognitive behavioral therapy; Drug · Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 60 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Depression, Adolescent - Emotional Problem, Stigma, Social, Help-Seeking Behavior
Interventions: brief video; Other
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 14 Years to 18 Years
Enrollment: 645 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Neuralgia Peripheral, Pain
Interventions: Gabapentin, BTACT, BPI, HADS, SLP9, NPSI; Drug · Diagnostic Test
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 85 Years
Enrollment: 3 participants
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Major Depressive Episode, Bipolar Depression, Bipolar Disorder, Mood Disorders
Interventions: NEST (NeoSync EEG Synchronized TMS); Device
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Depression
Interventions: transcranial direct current stimulation, iomed phoresor transcranial direct current stimulation; Device
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 85 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

The Staying Well Study: An Open Trial of Mindfulness-Based Cognitive Therapy for the Prevention of Perinatal Depression

Buprenorphine for Treatment Resistant Depression

Improving Social, Emotional, Behavioral, and Academic Functioning

Comparison of Two Forms of Oxcarbazepine for the Treatment of Bipolar Depression

Pharmacologic Treatment of PTSD in Sexually Abused Children

fMRI-neuronavigated rTMS Treatment for Symptoms of Depression Associated With Concussive TBI in the Military Population

Closed-Loop Deep Brain Stimulation for Major Depression

Long Term Follow Up KET-PD

Cognitive Behavioral Therapy (CBT) for Adherence and Depression in Type 1 Diabetes

Improving Mental Health Among the LGBTQ+ Community

Supporting Our Valued Adolescents Pilot Randomized Controlled Trial

Ketamine for Older Adults Pilot

Digital Therapeutic vs Educational App for Depression Among Adolescents

Effect of Guided Imagery for Radiotherapy-Related Distress in Patients With Head and Neck Cancer

Online Study on the Impact of a Self-Help Tool for Social Anxiety

Effect of Family-Based Prevention on Children of Depressed Parents

A Relative Bioavailability Food Effect Study of LY03005

Practicing Alternative Techniques to Heal From Depression: The PATH-D Study

Brain Imaging of Psychotherapy for Depression

Psilocybin-assisted CBT for Depression

RCT of a Brief Video Intervention Targeting Peer Inclusion to Reduce Depression-related Stigma in Adolescents

Cognitive Changes With Gabapentin Treatment

NeoSync TMS Treatment for Bipolar I Depression

Treating Depression With Transcranial Direct Current Stimulation (tDCS)