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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:59 AM EDT

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Showing 1225–1248 of 3,101 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Treatment of depression Clear all
Completed Phase 2 Interventional Results available

Telephone Administered Psychotherapy for the Treatment of Depression for Veterans in Rural Areas

NCT00223652
View directory record Official record
Conditions
Depressive Disorder, Depression
Interventions
Telephone cognitive behavioral therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
3
States / cities
San Francisco, California • Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 24, 2015 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Community Resilience Learning Collaborative and Research Network

NCT03977844
View directory record Official record
Conditions
Depression, Social Stress, Anxiety, Quality of Life, Disaster
Interventions
Technical Assistance, Community Engagement and Planning, Community Resources (CR), Community Resources + eBT
Other
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
258 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated May 24, 2021 · Synced Oct 21, 2026, 5:59 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

The Effects of Trauma-sensitive Yoga and Tai Chi on Mental Health

NCT04754009
View directory record Official record
Conditions
Mental Health Wellness 1
Interventions
Trauma-Sensitive Yoga + TAU, Chen Style Tai Chi + TAU, Treatment as Usual
Behavioral
Lead sponsor
University of Northern Iowa
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Cedar Falls, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 24, 2021 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Not applicable Interventional

Motivational Interviewing to Increase Physical Activity to Treat Depression in People Aging With MS or SCI

NCT00947232
View directory record Official record
Conditions
Multiple Sclerosis, Spinal Cord Injury
Interventions
Motivational interviewing, Education
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
45 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 5, 2017 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Not applicable Interventional

Personalized Depression Treatment Supported by Mobile Sensor Analytics

NCT06292221
View directory record Official record
Conditions
Depression
Interventions
A mobile Health (mHealth) tool called 'DepWatch'
Other
Lead sponsor
UConn Health
Other
Eligibility
Not listed
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Oct 21, 2026, 5:59 AM EDT
Suspended Not applicable Interventional

Low-Intensity Focused Ultrasound for Treatment-Resistant Depression

NCT06013384
View directory record Official record
Conditions
Major Depressive Disorder, Treatment Resistant Depression
Interventions
Low-Intensity Focused Ultrasound Pulsation, Sham Low-Intensity Focused Ultrasound Pulsation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 21, 2026, 5:59 AM EDT
Active, not recruiting No phase listed Observational

Surgery Versus Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer

NCT05183932
View directory record Official record
Conditions
Non Small Cell Lung Cancer, Non-small Cell Lung Cancer
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
446 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
7
States / cities
Atlanta, Georgia • Urbana, Illinois • St Louis, Missouri + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Phase 2 Interventional Results available

The Use of a Mitochondrial Enhancement Treatment in Bipolar Disorder

NCT00719706
View directory record Official record
Conditions
Bipolar Depression
Interventions
acetyl-l-carnitine PLUS alpha-lipoic acide, Placebo
Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 18, 2012 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Early Phase 1 Interventional

fMRI Study of tES in Major Depression

NCT04031547
View directory record Official record
Conditions
Depression
Interventions
Transcranial Electrical Stimulation (tES)
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Phase 2 Interventional

Clinical and Cost Effectiveness of Brief Cognitive-Behavioral Therapy (CBT) for Pediatric Internalizing Disorders

NCT00669526
View directory record Official record
Conditions
Depression, Anxiety
Interventions
BCBT, SMHC referral
Behavioral
Lead sponsor
Robert Wood Johnson Foundation
Other
Eligibility
7 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2008 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Not applicable Interventional

Improving Physical Activity Maintenance of Cancer Survivors

NCT03976193
View directory record Official record
Conditions
Cancer
Interventions
BfitBwell program, 6 bi-weekly PA Behavior Change counseling sessions
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Not listed
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 17, 2023 · Synced Oct 21, 2026, 5:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Outcomes Following Surf Therapy

NCT02857751
View directory record Official record
Conditions
Depression, Posttraumatic Stress Disorder
Interventions
Surf therapy
Behavioral
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2021 · Synced Oct 21, 2026, 5:59 AM EDT
Completed No phase listed Observational

Using Neuroimaging to Investigate Major Depressive Disorder

NCT00781677
View directory record Official record
Conditions
Major Depressive Disorder, Depression, Anxiety
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Behavioral Intervention for Low Income Depressed Smokers in Drug Treatment

NCT01372254
View directory record Official record
Conditions
Cigarette Smoking, Drug Use
Interventions
Standard Treatment, BAD-AS, Transdermal Nicotine Patch
Behavioral · Drug
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Phase 2 Interventional

Efficacy and Safety of Fixed Doses of BMS 820836 in the Treatment of Patients With Treatment Resistant Major Depression

NCT01369095
View directory record Official record
Conditions
Depression
Interventions
Duloxetine, Escitalopram, BMS-820836 Placebo, BMS-820836
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years to 65 Years
Enrollment
976 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
48
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Chino, California + 41 more
Source: ClinicalTrials.gov public record
Updated Oct 12, 2015 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Not applicable Interventional

Practical Application of Accelerated iTBS for MDD

NCT06113575
View directory record Official record
Conditions
Major Depressive Disorder, Major Depressive Disorder, Recurrent Episode, Severe, Major Depressive Disorder, Recurrent, Moderate
Interventions
NeuroStar TMS
Device
Lead sponsor
Sonder Behavioral Health and Wellness
Other
Eligibility
22 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Minnetonka, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 21, 2026, 5:59 AM EDT
Recruiting Not applicable Interventional

Preoperative Opioid Tapering Before Spine Surgery

NCT07221786
View directory record Official record
Conditions
Opioid Consumption, Postoperative, Pain After Surgery, Opioid Dependency
Interventions
Opioid tapering with CBT and education, Opioid tapering with education alone
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Philadephia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Phase 2 Interventional Results available

N-Acetyl Cysteine and Aspirin as an Adjunctive Treatment for Bipolar Disorder

NCT01797575
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Aspirin, N-acetyl-cysteine (NAC), Sugar Pill
Drug · Dietary Supplement
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Phase 1Phase 2 Interventional

Virtual Reality (VR) Therapy for Post-Traumatic Stress Disorder (PTSD)

NCT00992953
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Treatment as Usual, Virtual Reality Exposure with Stimulus Control
Behavioral
Lead sponsor
Office of Naval Research (ONR)
Federal
Eligibility
18 Years to 65 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
2
States / cities
Camp Pendlton, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2009 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Not applicable Interventional

Bright White Light Therapy for the Improvement of Sleep, Fatigue, Distress, Depression, and Anxiety in Hospitalized Leukemia Patients

NCT04597086
View directory record Official record
Conditions
Acute Leukemia, Recurrent Leukemia, Refractory Leukemia
Interventions
Best Practice, Bright White Light Therapy, Survey Administration
Other · Procedure
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
Not listed
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 7, 2023 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Phase 2 Interventional

An 8 Week Depression Study In Adults Diagnosed With Major Depressive Disorder

NCT00057239
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
Radafaxine
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 64 Years
Enrollment
546 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
29
States / cities
Little Rock, Arkansas • Newport Beach, California • Farmington, Connecticut + 25 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2010 · Synced Oct 21, 2026, 5:59 AM EDT
Completed Not applicable Interventional Results available

Treating Major Depression With Yoga: A Prospective, Randomized Controlled Pilot Trial

NCT01210651
View directory record Official record
Conditions
Depression, Unipolar
Interventions
Hatha Yoga Practice Group, Attention Control Education Group
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
14 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Oct 21, 2026, 5:59 AM EDT
Not listed Not applicable Interventional

Pharmacogenetic Decision Support IT System for Psychiatric Hospitalization: RCT

NCT02120729
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Genotype-guided care
Other
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 95 Years
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 12, 2019 · Synced Oct 21, 2026, 5:59 AM EDT
Terminated Phase 4 Interventional Results available

Promoting Enhanced Pharmacotherapy Choice Through Immunomarkers Evaluation in Depression

NCT03993457
View directory record Official record
Conditions
Depression
Interventions
Escitalopram, Bupropion
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 21, 2026, 5:59 AM EDT