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ClinicalTrials.gov public records Last synced Oct 23, 2026, 10:38 PM EDT

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Showing 1345–1368 of 3,102 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Treatment of depression Clear all
Completed Not applicable Interventional

Magnesium Sulfate Versus 5% Dextrose With Treatment Resistant Depression

NCT01597167
View directory record Official record
Conditions
Depression
Interventions
Magnesium sulfate
Dietary Supplement
Lead sponsor
University of Miami
Other
Eligibility
21 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 21, 2016 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Phase 2 Interventional

Intervention for Depressed Latina Mothers of Children With Asthma

NCT01326182
View directory record Official record
Conditions
Pediatric Asthma, Maternal Depression
Interventions
MAADRE, MAAS
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Not applicable Interventional

Media Project and Health Study - Spanish Version

NCT04862624
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Catalina Story-Based Web-App, Attention Control Web-App
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 50 Years · Female only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Oct 23, 2026, 10:38 PM EDT
Terminated Phase 4 Interventional Results available

A Study of the Efficacy of Botox in the Treatment of Social Anxiety Disorder

NCT03078270
View directory record Official record
Conditions
Anxiety Disorder Social, Anxiety
Interventions
botulinum toxin A, Placebo
Drug · Other
Lead sponsor
Daniel Lieberman
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 23, 2019 · Synced Oct 23, 2026, 10:38 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Two Sessions of Coach-Delivered Core Transformation for Distress and Well-Being

NCT07879196
View directory record Official record
Conditions
Psychological Distress, Psychological Well-being
Interventions
Core Transformation Process
Behavioral
Lead sponsor
Andreas NLP (Legal Entity - Real People Press)
Other
Eligibility
18 Years and older
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Pharmacodynamic Evaluation of Intramuscular Nalmefene Autoinjector 1.5 mg Compared to Intranasal Narcan 4 mg

NCT06719986
View directory record Official record
Conditions
Opioid Overdose
Interventions
Nalmefene HCl injection, Naloxone HCl intranasal
Drug
Lead sponsor
Purdue Pharma LP
Industry
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Not applicable Interventional

Collaborative Care to Alleviate Symptoms and Adjust to Illness in Chronic Heart Failure (CASA) Trial

NCT01739686
View directory record Official record
Conditions
Chronic Heart Failure
Interventions
CASA Intervention
Other
Lead sponsor
Denver Research Institute
Other
Eligibility
18 Years and older
Enrollment
317 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
3
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 1, 2017 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Phase 1Phase 2 Interventional

Effects of Therapist Behavior on the Treatment of Depressed Adolescents

NCT00073359
View directory record Official record
Conditions
Depression, Depressive Disorder, Dysthymic Disorder
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Denver
Other
Eligibility
13 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 19, 2019 · Synced Oct 23, 2026, 10:38 PM EDT
Active, not recruiting No phase listed Observational

Long-Term Follow-Up in Women With Early Breast Cancer Three Years of More Post Primary Treatment

NCT05926024
View directory record Official record
Conditions
Breast Cancer
Interventions
Exercise Recall Patient Reported Outcomes, Health Behavior Questionnaire (HBQ)30 Patient Reported Outcomes, Functional Assessment of Cancer Therapy-General (FACT-G) Patient Reported Outcomes, Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) Patient Reported Outcomes, Patient Reported Outcomes PROMIS Cognitive Function (Short Form 8a), Patient Reported Outcomes Functional Assessment of Cancer-Gynecology Oncology Group-Neurotoxicity (FACT/GOG-NTX-12), Patient Reported Outcomes PROMIS, Patient Reported Outcomes FACT-Endocrine Symptoms, Patient Reported Outcomes Penn Arthralgia Aging Survey, Patient Reported Outcomes PRO-CTCAE (patient-reported CTCAE), p16 tumor suppressor gene
Behavioral · Diagnostic Test
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
21 Years and older · Female only
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Phase 2 Interventional Results available

Neurosteroids for Treatment of PTSD in Veterans

NCT03799562
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Pregnenolone, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 23, 2026, 10:38 PM EDT
Not listed Not applicable Interventional

Transdiagnostic Individual Behavioral Activation and Exposure Therapy

NCT03412227
View directory record Official record
Conditions
Anxiety Disorders, Depression
Interventions
Individual Behavioral Activation Therapy (IBAT), The PASCET Program for Youth Depressive Disorders, The Coping Cat Program for Youth Anxiety Disorders, 14-week waitlist (WL) condition
Behavioral · Other
Lead sponsor
Rutgers University
Other
Eligibility
9 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Phase 2 Interventional

Examination of a Soy-Based Supplement for Major Depression

NCT00042380
View directory record Official record
Conditions
Depression
Interventions
Novasoy
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Image Narrative With College Students

NCT04759313
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Image Narrative
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 29 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 3, 2023 · Synced Oct 23, 2026, 10:38 PM EDT
Recruiting Phase 2 Interventional

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

NCT06376734
View directory record Official record
Conditions
Major Depressive Disorder, Obsessive-Compulsive Disorder, Schizophrenia, Generalized Anxiety Disorder, Mood Disorders, Psychiatric Disorder, Mental Disorder, Depression, Anxiety
Interventions
Transcranial magnetic stimulation
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
Sunnyvale, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Not applicable Interventional

Comparative Effectiveness Research for Eliminating Disparities

NCT02027636
View directory record Official record
Conditions
Depression
Interventions
Engagement and Counseling for Latinos (ECLA-F), Engagement and Counseling for Latinos (ECLA-T)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
257 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2016 · Synced Oct 23, 2026, 10:38 PM EDT
Terminated Not applicable Interventional

Investigating Effects of High-intensity Gait Training on Gait, Balance and Depression Post-stroke

NCT06373107
View directory record Official record
Conditions
Stroke
Interventions
High intensity gait training
Behavioral
Lead sponsor
Alvernia University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Chicago Urban Resiliency Building (CURB)

NCT01571011
View directory record Official record
Conditions
Major Depression
Interventions
CURB
Behavioral
Lead sponsor
Benjamin Van Voorhees, MD, MPH
Other
Eligibility
13 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Depression Prevention Program for Adolescents

NCT00183417
View directory record Official record
Conditions
Depression
Interventions
Cognitive behavior therapy (CBT), Supportive/expressive (S/E) therapy, Bibliotherapy
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
14 Years to 18 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2012 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Not applicable Interventional Results available

Technology Enabled Services to Enhance Depression Care

NCT05406791
View directory record Official record
Conditions
Depression, Anxiety
Interventions
VIRA App, Mood Education App
Other
Lead sponsor
Northwestern University
Other
Eligibility
13 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Not applicable Interventional

Effectiveness of Parent-Child Interaction and Emotion Development Therapy in Treating Preschool Children With Depression

NCT00595283
View directory record Official record
Conditions
Depression
Interventions
Parent Child Interaction Therapy-Emotion Development (PCIT-ED), Developmental Education Parenting Intervention (DEPI)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
3 Years to 6 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 22, 2013 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Not applicable Interventional

Neurocognitive Predictors of Behavioral Therapy Response in Depression

NCT02602340
View directory record Official record
Conditions
Depression
Interventions
Behavioral Activation therapy
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 25, 2020 · Synced Oct 23, 2026, 10:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder

NCT03336918
View directory record Official record
Conditions
Bipolar Disorder, Bipolar I Depression, Bipolar II Depression, Bipolar Depression, Depression, Major Depressive Episode
Interventions
Lithium
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 23, 2026, 10:38 PM EDT
Recruiting Not applicable Interventional

Suicidal Behavior in Patients Diagnosed With Bipolar Disorder

NCT02604277
View directory record Official record
Conditions
Depression, Alcoholism, Drug Abuse
Interventions
Interpersonal and Social Rhythm Therapy (ISRT), Bipolar-Specific Cognitive Behavioral Therapy (CBT), Mindfulness-Based Stress Reduction (MBSR), Psycho-education & Understanding Bipolar Medications Therapy
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 64 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 23, 2026, 10:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of Telehealth Problem-Solving Therapy for Depressed Homebound Older Adults

NCT00903019
View directory record Official record
Conditions
Depression
Interventions
Tele-Problem-Solving Therapy, In-Person PST, Attention control
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
50 Years and older
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2015 · Synced Oct 23, 2026, 10:38 PM EDT