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ClinicalTrials.gov public records Last synced Oct 28, 2026, 11:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1633–1656 of 3,106 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Treatment of depression Clear all
Completed Not applicable Interventional Results available

Pilot Randomized Controlled Trial (RCT): Remote SBIRT Vs. In-Person SBIRT

NCT04630249
View directory record Official record
Conditions
Pregnancy, Substance Use, Depression, Anxiety
Interventions
Listening to Women and Pregnant and Postpartum People
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 41 Years · Female only
Enrollment
415 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 18, 2024 · Synced Oct 28, 2026, 11:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural and Visual Responses to Light in Bipolar Disorder: A Novel Putative Biomarker

NCT02048995
View directory record Official record
Conditions
Bipolar Depression
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 50 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 28, 2026, 11:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

We The Village Family Support Study

NCT04250077
View directory record Official record
Conditions
Community Reinforcement And Family Training, Family Health, Substance-Related Disorders
Interventions
Community Reinforcement And Family Training (CRAFT), We The Village Peer Community Forum
Behavioral
Lead sponsor
We The Village, Inc.
Other
Eligibility
19 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 28, 2026, 11:13 PM EDT
Recruiting Not applicable Interventional

Tele-PROTECT Therapy: Effectiveness, Empowerment, and Implementation

NCT06039930
View directory record Official record
Conditions
Depression, Elder Abuse
Interventions
Tele PROTECT, Depression Education
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 28, 2026, 11:13 PM EDT
Completed Not applicable Interventional

Depression Decision Aid: Feasibility Pilot

NCT02239367
View directory record Official record
Conditions
Depression
Interventions
Depression Decision Aid
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
21 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2017 · Synced Oct 28, 2026, 11:13 PM EDT
Recruiting No phase listed Observational

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

NCT06683092
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
RETRIAL-Mental Health, RETRIAL-Liver, RETRIAL-Neuro
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
18
States / cities
Birmingham, Alabama • Aurora, Colorado • Denver, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Oct 28, 2026, 11:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Positive Family Support Project - Partnering With Families for a Successful Transition to School

NCT02289092
View directory record Official record
Conditions
Achievement
Interventions
Family Check-Up
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
Not listed
Enrollment
848 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Oct 28, 2026, 11:13 PM EDT
Terminated No phase listed Observational

Cognitive Changes With Gabapentin Treatment

NCT04106011
View directory record Official record
Conditions
Neuralgia Peripheral, Pain
Interventions
Gabapentin, BTACT, BPI, HADS, SLP9, NPSI
Drug · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
3 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Oct 28, 2026, 11:13 PM EDT
Completed Not applicable Interventional

Multiple Sclerosis-Collaborative Approach to Rehabilitation Effectiveness Study

NCT02137044
View directory record Official record
Conditions
Multiple Sclerosis, Pain, Depression
Interventions
Collaborative Care (CC)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Oct 28, 2026, 11:13 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Cyrolipolysis vs Cyrolipolysis and Subcision for Cellulite

NCT02427698
View directory record Official record
Conditions
Cellulite
Interventions
cyrolipolysis (CoolSculpting device), subcision
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 28, 2026, 11:13 PM EDT
Completed Phase 4 Interventional Results available

Safety Study of Escitalopram in Children 7 to 11 Years of Age With Major Depressive Disorder

NCT01198795
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Escitalopram
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
7 Years to 11 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
16
States / cities
Dothan, Alabama • San Diego, California • Santa Ana, California + 13 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2014 · Synced Oct 28, 2026, 11:13 PM EDT
Completed Not applicable Interventional Results available

Measuring Quality of Decisions About Treatment of Depression

NCT01152307
View directory record Official record
Conditions
Depression
Interventions
DVD/Booklet: Coping with Symptoms of Depression
Behavioral
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
18 Years and older
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2012 · Synced Oct 28, 2026, 11:13 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Rapid Antidepressant Effects of Ketamine in Major Depression

NCT00088699
View directory record Official record
Conditions
Depression, Mood Disorders, Major Depresssion
Interventions
Ketamine, Placebo
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 12, 2018 · Synced Oct 28, 2026, 11:13 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety, Tolerability, PK and Efficacy of Single Doses of NV-5138 in Healthy Volunteers and Subjects With Treatment-Resistant Depression

NCT03606395
View directory record Official record
Conditions
Treatment Resistant Depression
Interventions
NV-5138, Placebos
Drug
Lead sponsor
Navitor Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
9
States / cities
Birmingham, Alabama • Long Beach, California • San Diego, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Oct 28, 2026, 11:13 PM EDT
Completed Phase 3 Interventional Results available

Randomized, Double-Blind, Placebo Controlled Study of Vilazodone's Efficacy, Safety, and Biomarkers of Response in Major Depressive Disorder (MDD)

NCT00683592
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
vilazodone, placebo
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years to 70 Years
Enrollment
481 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
9
States / cities
Newport Beach, California • Bradenton, Florida • Atlanta, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2010 · Synced Oct 28, 2026, 11:13 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Addressing Mental Health in African American Job Training Adolescents and Young Adults

NCT00979524
View directory record Official record
Conditions
Depression
Interventions
Comprehensive Mental Health Services and Supports
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
16 Years to 24 Years
Enrollment
782 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 7, 2016 · Synced Oct 28, 2026, 11:13 PM EDT
Completed Not applicable Interventional

Process and Outcomes in CBT for Anxious and Depressed Youth

NCT03100279
View directory record Official record
Conditions
Anxiety Disorders, Depression
Interventions
Coping Cat/CAT Project, Primary and Secondary Coping Enhancement Therapy
Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
7 Years to 17 Years
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2020
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 28, 2026, 11:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Sleep Intervention for Cancer Patients and Their Caregivers

NCT04969146
View directory record Official record
Conditions
Intervention, Control
Interventions
Dyadic Intervention, Patient Only Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 28, 2026, 11:13 PM EDT
Recruiting Not applicable Interventional

Targeted Accelerated TMS for Post-Traumatic Stress Disorder

NCT07245641
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD)
Interventions
Transcranial Magnetic Stimulation
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 28, 2026, 11:13 PM EDT
Completed Not applicable Interventional

Rise Study for Depression

NCT06003361
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Digital CBT, Waitlist
Device · Other
Lead sponsor
Big Health Inc.
Industry
Eligibility
22 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Oct 28, 2026, 11:13 PM EDT
Recruiting No phase listed Observational

Depression and Driving

NCT05446805
View directory record Official record
Conditions
Depression, Drive
Interventions
F 18 AV-1451 (Flortaucipir), [11C]-Pittsburgh Compound B ([11C]PiB)
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years and older
Enrollment
150 participants
Timeline
2021 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 28, 2026, 11:13 PM EDT
Recruiting Not applicable Interventional

Attenuating DEPression With Internet CBT to Slow Cognitive Decline in Older ICU Survivors(ADEPT-ICU)

NCT06627894
View directory record Official record
Conditions
Depression, Cognitive Decline
Interventions
Therapist-Assisted Internet Cognitive-Behavioral Therapy for Depression, Active Control
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
50 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 28, 2026, 11:13 PM EDT
Terminated Phase 1 Interventional

Allogeneic Human Mesenchymal Stem Cells (hMSCs) Infusion in Patients With Treatment Resistant Depression

NCT02675556
View directory record Official record
Conditions
Treatment Resistant Depression
Interventions
Allo-hMSCs, Placebo
Drug
Lead sponsor
Joshua M Hare
Other
Eligibility
18 Years to 75 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 1, 2019 · Synced Oct 28, 2026, 11:13 PM EDT
Terminated Phase 2Phase 3 Interventional

SAINT for MDD in an Inpatient Setting Follow-on

NCT06462820
View directory record Official record
Conditions
Major Depressive Disorder, Major Depressive Episode, Suicidal Ideation
Interventions
Active SAINT Stimulation, Sham SAINT Stimulation
Device
Lead sponsor
Magnus Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Iowa City, Iowa • Manhattan, New York • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Oct 28, 2026, 11:13 PM EDT