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ClinicalTrials.gov public records Last synced Oct 29, 2026, 11:03 AM EDT

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Showing 1705–1728 of 3,106 matching trials from the live ClinicalTrials.gov search.
Conditions
Depression, Anxiety, Loneliness
Interventions
Stay Connected, Treatment as usual
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
60 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Recruiting Phase 2 Interventional Accepts healthy volunteers

JAK Signaling in Depression and Cognition in Male Football Players

NCT07608796
Conditions
Depressive Symptoms, Cognitive Symptom
Interventions
Baricitinib
Drug
Lead sponsor
Emory University
Other
Eligibility
30 Years to 55 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Atlanta, Georgia
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Impact of Giving a Massage

NCT01169480
Conditions
Mental State, Reported as Depression, Anxiety or Stress
Interventions
Give a massage
Behavioral
Lead sponsor
Parker Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Unilateral Massage as a Potential Treatment for Depression

NCT01937897
Conditions
Depression
Interventions
Bi-lateral massage
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tucson, Arizona
Conditions
Major Depressive Disorder, Parkinson's Disease
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Amy Farabaugh, PhD
Other
Eligibility
40 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Behavioral Activation Intervention Administered in a College Freshman Orientation Course

NCT04038190
Conditions
Alcohol; Use, Problem, Stress, Binge Eating, Depression
Interventions
behavioral activation
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
17 Years and older
Enrollment
572 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Lawrence, Kansas
Completed Not applicable Interventional Results available

PRIME Care (PRecision Medicine In MEntal Health Care)

NCT03170362
Conditions
Major Depression
Interventions
Pharmacogenetic Test
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
1,944 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
24
States / cities
North Little Rock, Arkansas • Palo Alto, California • San Francisco, California + 21 more
Conditions
Opioid-use Disorder, Anxiety, Depression, Stress Related Disorder
Interventions
M-ROCC
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Somerville, Massachusetts
Conditions
Major Depressive Disorder, Bipolar Depression
Interventions
Xenon, Nitrogen gas
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Mindfulness Based Cognitive Therapy (MBCT) Maintenance

NCT05859386
Conditions
Depression
Interventions
Mindfulness maintenance program
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Francisco, California
Conditions
Bipolar Disorder
Interventions
IPSRT, Collaborative Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Major Depressive Disorder
Interventions
saredutant (SR48968), escitalopram, placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years to 65 Years
Enrollment
643 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Bridgewater, New Jersey
Conditions
Depression, Cognition
Interventions
Duloxetine, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
65 Years and older
Enrollment
311 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
Middleton, Wisconsin
Conditions
Post Traumatic Stress Disorders, Unsafe Sex, Substance Use Disorders
Interventions
Cognitive Processing Therapy-Cognitive
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Toppenish, Washington
Conditions
Cirrhosis
Interventions
Transcutaneous Electrical Acustimulation (TEA), Sham Transcutaneous Electrical Acustimulation (TEA)
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Evaluating the Effects of a Fermented Diet on Microbiome Diversity in Individuals With Long COVID

NCT06560554
Conditions
Long COVID
Interventions
Fermented foods, Control
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Adolescent, Depression, Substance Use Disorders
Interventions
Adolescent Coping With Depression/Functional Family Therapy
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 17 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Eugene, Oregon
Conditions
Hypogonadism, Late Onset Hypogonadism, Low Testosterone
Interventions
Dihydrotestosterone (0.7%) in hydroalcoholic gel
Drug
Lead sponsor
ASCEND Therapeutics
Industry
Eligibility
55 Years to 80 Years · Male only
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
16
States / cities
Phoenix, Arizona • Torrance, California • Gainesville, Florida + 13 more
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Cardiovascular Biomarkers and Quetiapine in Depression and Anxiety Patients

NCT00951483
Conditions
Depression, Anxiety
Interventions
Quetiapine-XR
Drug
Lead sponsor
Loyola University
Other
Eligibility
20 Years to 65 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Maywood, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Veterans Coping Long-term With Active Suicide

NCT01894841
Conditions
Suicide
Interventions
Coping Long Term with Active Suicide (CLASP), Safety Assessment and Follow Up Evaluation
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Alcoholism, Alcohol Drinking, Drinking Behavior, Alcohol-Related Disorders, Substance-Related Disorders, Mental Disorder, Anxiety, Depression
Interventions
Amplification of Positivity Training, Cognitive-behavioral Therapy
Behavioral
Lead sponsor
Charles Taylor
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
La Jolla, California • Tulsa, Oklahoma
Conditions
Fatigue, Febrile Neutropenia, Solid Neoplasm
Interventions
Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Houston, Texas
Completed Phase 2 Interventional Results available

Nuedexta in Treatment-Resistant Major Depression

NCT01882829
Conditions
Major Depressive Disorder, Treatment Resistant
Interventions
dextromethorphan/quinidine
Drug
Lead sponsor
James Murrough
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Not listed Not applicable Interventional Accepts healthy volunteers

Building Resilience In Caregivers of Trauma Survivors

NCT04293016
Conditions
Caregiver Burnout
Interventions
Support as usual, Problem solving therapy, ICU diary
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 70 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas