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ClinicalTrials.gov public records Last synced Oct 24, 2026, 6:32 PM EDT

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Showing 1–24 of 36 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Trigger Point Dry Needling Clear all
Completed Not applicable Interventional

Effects of Dry Needling Using Spinal and Peripheral Sites Versus Peripheral Sites Only

NCT02646579
View directory record Official record
Conditions
Plantar Fasciitis, Achilles Tendinitis, Patellofemoral Pain Syndrome
Interventions
Spinal and Peripheral Dry Needling, Peripheral Dry Needling
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Immediate Effect of Dry Needling of the Lumbar Multifidus on Pain Sensitivity In A Healthy Population

NCT05845697
View directory record Official record
Conditions
Low Back Pain
Interventions
Trigger point dry needling, Sham dry needling
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Oct 24, 2026, 6:32 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Derivation of a Clinical Prediction Rule to Identify Those With Low Back Pain Who Will Respond Favorably to Intramuscular Dry-needling

NCT06204055
View directory record Official record
Conditions
Low Back Pain
Interventions
Intramuscular Dry-Needling
Other
Lead sponsor
Whitworth University
Other
Eligibility
18 Years to 60 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Jan 12, 2024 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pain and Neck Dysfunction Following Dry Needling With and Without Intramuscular Electrical Stimulus.

NCT04057781
View directory record Official record
Conditions
Neck Pain, Shoulder Pain, Myofascial Pain
Interventions
Dry Needling (DN), Dry needling with Intramuscular electrical stimulation (DNES)
Procedure
Lead sponsor
University of Mary Hardin-Baylor
Other
Eligibility
18 Years to 59 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Belton, Texas
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Dry Needling Multifidus on Thickness of Transversus Abdominis in Healthy Individuals

NCT01734577
View directory record Official record
Conditions
Back Pain
Interventions
Dry needling, Sham needling
Procedure
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jun 19, 2013 · Synced Oct 24, 2026, 6:32 PM EDT
Not yet recruiting Not applicable Interventional

Dry Needling and Quad Strength After Anterior Cruciate Ligament Reconstruction

NCT07657195
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction Rehabilitation, Dry Needling, Strength
Interventions
Dry Needling
Procedure
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
10 Years to 20 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Kansas City, Kansas • Overland Park, Kansas • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Dry Needling on Muscle Stiffness, Gait, Motion, and Strength in Healthy Individuals With Trigger Points

NCT03689283
View directory record Official record
Conditions
Trigger Point Pain, Myofascial
Interventions
Dry Needling, Sham Dry Needlling
Other
Lead sponsor
Regis University
Other
Eligibility
18 Years to 50 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Oct 24, 2026, 6:32 PM EDT
Recruiting Not applicable Interventional

Multi-modal Imaging of Myofascial Pain - Phase 2

NCT07322445
View directory record Official record
Conditions
Myofascial Pain
Interventions
50/50 Mixture of Lidocaine 1% injection + Bupivacaine 0.25% Injectable Solution, Dry Needling
Drug · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional

Intramuscular Electrical Stimulation for the Treatment of Trigger Points in Patients With Migraine

NCT05893914
View directory record Official record
Conditions
Chronic Migraine
Interventions
Dry Needling and intramuscular electrical stimulation to trigger points
Procedure
Lead sponsor
Thomas W. Perreault, PT
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Dover, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

QUANTIFY: Quantitative Understanding of Advanced Novel Techniques for Imaging Fasciitis and Yielding Biomarkers

NCT06803056
View directory record Official record
Conditions
Plantar Fasciopathy, Achilles Tendinopathy, Controls
Interventions
Clinical exam, Ultrasound imaging, Magnetic Resonance Imaging
Diagnostic Test
Lead sponsor
Ruth Chimenti
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trigger Point Dry Needling Practice in Colorado: Practitioner and Patient

NCT04040218
View directory record Official record
Conditions
Dry Needling, Harm
Interventions
Dry Needling
Procedure
Lead sponsor
Regis University
Other
Eligibility
18 Years and older
Enrollment
2,607 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dry Needling in Subjects With Delayed Onset Muscle Soreness

NCT03876080
View directory record Official record
Conditions
Delayed Onset Muscle Soreness
Interventions
Dry needling, Sham needling
Other
Lead sponsor
Bradley University
Other
Eligibility
18 Years to 35 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional

Dry Needling at the Thoracolumbar Junction on Measures of Sympathetic Outflow and Flexibility

NCT03630172
View directory record Official record
Conditions
Low Back Pain
Interventions
Dry needling
Procedure
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 70 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kensington, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional

Dry Needling and Stretching vs. Stretching Alone on Hamstring Flexibility in Patients With Knee Pain

NCT02498704
View directory record Official record
Conditions
Mobility Limitation
Interventions
Dry Needling, Sham Needling
Procedure · Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional

The Effect of Needle Placement on Muscle Stiffness, Gait, Balance, Pain and Functional Outcomes in Individuals With Injury to the Ankle and/or Hindfoot

NCT04487327
View directory record Official record
Conditions
Ankle and or Hindfoot Injury
Interventions
Dry Needling
Other
Lead sponsor
Regis University
Other
Eligibility
18 Years to 60 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 10, 2023 · Synced Oct 24, 2026, 6:32 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques

NCT07112404
View directory record Official record
Conditions
Pain, Back Pain, Lower Back Pain, Quality of Life
Interventions
Dry Needling, Dry needling with high-rate PENS, Dry needling with low-rate PENS
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional

A Mediation Analysis Investigating Dry Needling Treatment Mechanisms in a Chronic Low Back Pain Population

NCT06940492
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP)
Interventions
Dry needling
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional

Short-Term Response of Thoracic Spine Manipulation With or Without Trigger Point Dry Needling for Mechanical Neck Pain

NCT02415660
View directory record Official record
Conditions
Neck Pain
Interventions
Thoracic spinal manipulation, Trigger point dry needling, Cervical range of motion exercises, Posterior neck muscle activation exercise, Trigger point dry needling sham, Seirin J-type stainless steel needles, 0-2-0.3 x 40-50 mm
Procedure · Behavioral · Device
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 64 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Oct 24, 2026, 6:32 PM EDT
Terminated Not applicable Interventional

Dry Needling for Shoulder Adhesive Capsulitis

NCT03861923
View directory record Official record
Conditions
Shoulder Adhesive Capsulitis, Shoulder Pain, Frozen Shoulder
Interventions
Dry needling, Sham Dry Needling, Therapeutic Exercise
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 24, 2026, 6:32 PM EDT
Recruiting Not applicable Interventional

Treatment Validation for Myofascial Pain

NCT07133139
View directory record Official record
Conditions
Chronic Low-back Pain (cLBP), Myofacial Pain
Interventions
Dry Needling, Sham Dry Needling, NUN Biomarker
Device · Other
Lead sponsor
Ajay Wasan, MD, Msc
Other
Eligibility
20 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 24, 2026, 6:32 PM EDT
Recruiting Not applicable Interventional

The Impact of Dry Needling on Electrophysiological and Ultrasound-based Biomarkers for Myofascial Pain

NCT07270276
View directory record Official record
Conditions
Trigger Point in Trapezius Muscle
Interventions
Dry Needling, Sham Treatment
Procedure
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Deep Trigger Point Dry Needling on Strength Measurements of the Gluteus Medius Musculature

NCT03580200
View directory record Official record
Conditions
Trigger Point, Muscle Weakness
Interventions
Trigger Point Dry Needling
Other
Lead sponsor
Emily Slaven, PT, PhD
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Oct 24, 2026, 6:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trigger Point Dry Needling With and Without Electrical Stimulation in Healthy Subjects

NCT07384247
View directory record Official record
Conditions
People With Identified Painful Trigger Points (Tp) Within the Soleus and Gastrocnemius Muscles Complex, Healthy Subjects or Volunteers
Interventions
Dry needling with electrical stimulation, Dry needling, Electrical stimulation, Sham
Procedure
Lead sponsor
University of Rhode Island
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Kingston, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 24, 2026, 6:32 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Peri-neural Electrical Dry Needling Migraine Treatment Study

NCT04252391
View directory record Official record
Conditions
Migraine Headache
Interventions
Perineural electrical dry needling, Standard Care
Procedure
Lead sponsor
Wheaton Franciscan Healthcare
Other
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 24, 2026, 6:32 PM EDT