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Showing 1–24 of 69 matching trials from the live ClinicalTrials.gov search.
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Conditions
Otorrhea, Otitis Media With Effusion in Children
Interventions
Otiprio, Ciprodex
Drug
Lead sponsor
Boston Medical Center
Other
Eligibility
6 Months to 10 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Healthy Volunteer
Interventions
Tymbion Lidocaine/epinephrine solution, Device: Iontophoresis System (IPS) with Drug: Tymbion lidocaine/epinephrine solution
Drug · Combination Product
Lead sponsor
Tusker Medical
Industry
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
2
States / cities
San Jose, California • Bethlehem, Pennsylvania
Conditions
Surgical Procedures, Operative
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Months to 30 Years
Enrollment
643 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Otitis Media With Effusion
Interventions
OTO-201, Sham
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
6 Months to 17 Years
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Diego, California
Conditions
Acute Otitis Media
Interventions
Moxidex otic solution, Moxifloxacin otic solution, Vehicle, Tympanostomy tubes
Drug · Other · Device
Lead sponsor
Alcon Research
Industry
Eligibility
6 Months to 12 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Otitis Media
Interventions
Intranasal fentanyl, morphine IM, IV morphine
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
6 Months to 6 Years
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Houston, Texas
Conditions
Otitis Media With Effusion
Interventions
bilateral myringotomy, bilateral myringotomy and tubes, adenoidectomy
Procedure
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
24 Months to 47 Months
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Results available

Hummingbird TTS Ear Tube Delivery Study

NCT02165384
Conditions
Otitis Media
Interventions
Ear tube placement with the Hummingbird TTS
Device
Lead sponsor
Preceptis Medical, Inc.
Industry
Eligibility
6 Months and older
Enrollment
199 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
4
States / cities
Maple Grove, Minnesota • Minneapolis, Minnesota • Rochester, Minnesota
Active, not recruiting Not applicable Interventional

In-Office Clinical Study of the Solo+ TTD

NCT05741333
Conditions
Ear Infection, Otitis Media
Interventions
Solo+ Tympanostomy Tube Device (Solo+ TTD)
Device
Lead sponsor
AventaMed DAC
Industry
Eligibility
6 Months to 13 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
7
States / cities
Alexander City, Alabama • Huntsville, Alabama • Opelika, Alabama + 4 more
Conditions
Otitis Media, Otitis Media Chronic, Otitis Media Effusion, Otitis Media Recurrent, Otitis Media in Children
Interventions
CLiKX® Tympanostomy Tube Delivery System
Device
Lead sponsor
ClinQure, Inc.
Network
Eligibility
6 Months and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Louisville, Kentucky • Mesquite, Texas
Active, not recruiting Not applicable Interventional

Posterior vs. Anterior Tympanostomy Tube Placement

NCT06191562
Conditions
Otitis Media in Children, Chronic Otitis Media With Effusion, Recurrent Acute Otitis Media
Interventions
Tympanostomy tube
Device
Lead sponsor
David Chi, MD
Other
Eligibility
6 Months to 14 Years
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Sewickley, Pennsylvania
Completed Not applicable Interventional Results available

inVENT-visIOn Study

NCT01444391
Conditions
Otitis Media
Interventions
Tympanostomy tube placement (Acclarent iontophoresis device)
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
6 Months and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Port Saint Lucie, Florida
Conditions
Chronic Otitis Media
Interventions
Dexmedetomidine, Fentanyl, Midazolam
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Eustachian Tube Dysfunction, Endolymphatic Hydrops
Interventions
Nasal steroid, Myringotomy tube placement, Diuretic, Antihistamine, Low salt diet
Drug · Procedure · Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Otitis Media With Effusion, Food Hypersensitivity
Interventions
Food Allergy Testing, Adenoidectomy, BMT
Other · Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
Up to 4 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Pre Operative Sedation, Mask Acceptance, Post Operative Delerium
Interventions
Combination of Dexmedetomidine with Midazolam
Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
6 Months to 4 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Wilmington, Delaware
Conditions
OME - Otitis Media With Effusion, AOM - Acute Otitis Media
Interventions
Iontophoresis & tube placement, Tube placement
Combination Product · Device
Lead sponsor
Tusker Medical
Industry
Eligibility
6 Months to 12 Years
Enrollment
370 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
18
States / cities
Carlsbad, California • Roseville, California • San Jose, California + 14 more
Conditions
Otorrhea
Interventions
Not listed
Lead sponsor
Alcon Research
Industry
Eligibility
6 Months to 12 Years
Enrollment
1,389 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Otitis Media With Effusion
Interventions
OTO-201, Sham
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
6 Months to 17 Years
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Diego, California
Completed Not applicable Interventional Results available

Clinical Study of the Tympanostomy Tube Delivery System

NCT00939796
Conditions
Otitis Media With Effusion
Interventions
Acclarent Tympanostomy Tube Delivery System
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
Not listed
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
2
States / cities
Biloxi, Mississippi • San Antonio, Texas
Conditions
Otitis Media
Interventions
Ofloxacin otic solution
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Months to 10 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Waltham, Massachusetts
Conditions
Otitis Media Recurrent, Middle Ear Infection, Ear Infection
Interventions
Advanced Ultrasound Otoscope
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
0 Years to 12 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Houston, Texas
Completed Phase 2Phase 3 Interventional Results available

Evaluation of the Tympanostomy Tube Delivery System

NCT01202578
Conditions
Otitis Media With Effusion, Acute Otitis Media
Interventions
tympanostomy tube
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
6 Months and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
4
States / cities
Port Saint Lucie, Florida • Louisville, Kentucky • San Antonio, Texas + 1 more
Conditions
Otitis Media
Interventions
Tube Delivery System (TDS)
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
6 Months to 21 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Port Saint Lucie, Florida