- Conditions
- Otitis Media
- Interventions
- Acclarent Tympanostomy Tube Delivery System (TTDS).
- Device
- Lead sponsor
- Integra LifeSciences Corporation
- Industry
- Eligibility
- Not listed
- Enrollment
- 29 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 1
- States / cities
- Kirkland, Washington
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Showing 1–24
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- Conditions
- Eustachian Tube Dysfunction, Chronic Otitis Media
- Interventions
- Not listed
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2016
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Chronic Otitis Media
- Interventions
- Dexmedetomidine, Fentanyl, Midazolam
- Drug
- Lead sponsor
- Nationwide Children's Hospital
- Other
- Eligibility
- Not listed
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Healthy Volunteer
- Interventions
- Tymbion Lidocaine/epinephrine solution, Device: Iontophoresis System (IPS) with Drug: Tymbion lidocaine/epinephrine solution
- Drug · Combination Product
- Lead sponsor
- Tusker Medical
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017
- U.S. locations
- 2
- States / cities
- San Jose, California • Bethlehem, Pennsylvania
- Conditions
- Otitis Media, Otitis Media Chronic, Otitis Media Effusion, Otitis Media Recurrent, Otitis Media in Children
- Interventions
- CLiKX® Tympanostomy Tube Delivery System
- Device
- Lead sponsor
- ClinQure, Inc.
- Network
- Eligibility
- 6 Months and older
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 2
- States / cities
- Louisville, Kentucky • Mesquite, Texas
- Conditions
- Emergence Agitation, Pain
- Interventions
- Acetaminophen
- Drug
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 6 Months to 6 Years
- Enrollment
- 108 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- OME - Otitis Media With Effusion, AOM - Acute Otitis Media
- Interventions
- Iontophoresis & tube placement, Tube placement
- Combination Product · Device
- Lead sponsor
- Tusker Medical
- Industry
- Eligibility
- 6 Months to 12 Years
- Enrollment
- 370 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 18
- States / cities
- Carlsbad, California • Roseville, California • San Jose, California + 14 more
- Conditions
- Middle Ear Effusion, Otitis Media
- Interventions
- Laser otoscope examination
- Device
- Lead sponsor
- MSTATT LLC
- Industry
- Eligibility
- 6 Months to 18 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Otitis Media
- Interventions
- Acclarent Tympanostomy Tube Delivery system (TTDS)
- Device
- Lead sponsor
- Integra LifeSciences Corporation
- Industry
- Eligibility
- 6 Months and older
- Enrollment
- 85 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Otitis Media With Effusion
- Interventions
- bilateral myringotomy, bilateral myringotomy and tubes, adenoidectomy
- Procedure
- Lead sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
- NIH
- Eligibility
- 24 Months to 47 Months
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1997 – 2007
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Otitis Media
- Interventions
- Hummingbird Tympanostomy Tube System
- Device
- Lead sponsor
- Preceptis Medical, Inc.
- Industry
- Eligibility
- 6 Months to 5 Years
- Enrollment
- 109 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2021
- U.S. locations
- 4
- States / cities
- Minneapolis, Minnesota • Rochester, Minnesota • Saint Cloud, Minnesota
- Conditions
- Acute Otitis Media
- Interventions
- Ciprofloxacin 0.3% and dexamethasone 0.1% otic suspension
- Drug
- Lead sponsor
- Alcon Research
- Industry
- Eligibility
- 6 Months to 4 Years
- Enrollment
- 318 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Fort Worth, Texas
- Conditions
- Eustachian Tube Dysfunction
- Interventions
- ET Stress test, Sonotubometry, Forced Response Test (FRT), Inflation Deflation Test (IDT), Maneuver Sequence, 9-Step Test, Tubomanometry, Videoendoscopic assessment of ETF, Pressure chamber ET test
- Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 3 Years to 70 Years
- Enrollment
- 95 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2019
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Otitis Media
- Interventions
- Tympanostomy tube placement (Acclarent iontophoresis device)
- Device
- Lead sponsor
- Integra LifeSciences Corporation
- Industry
- Eligibility
- 6 Months and older
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Port Saint Lucie, Florida
- Conditions
- Otitis Media
- Interventions
- Tube Delivery System (TDS)
- Device
- Lead sponsor
- Integra LifeSciences Corporation
- Industry
- Eligibility
- 6 Months to 21 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Port Saint Lucie, Florida
- Conditions
- Myringotomy
- Interventions
- Dexmedetomidine
- Drug
- Lead sponsor
- Martin Mueller
- Other
- Eligibility
- 1 Year to 10 Years
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Bilateral Middle Ear Effusion Requiring Tympanostomy Tube Placement
- Interventions
- OTO-201, Placebo, Sham
- Drug
- Lead sponsor
- Otonomy, Inc.
- Industry
- Eligibility
- 6 Months to 12 Years
- Enrollment
- 83 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Otitis Media With Effusion, Acute Otitis Media
- Interventions
- tympanostomy tube
- Device
- Lead sponsor
- Integra LifeSciences Corporation
- Industry
- Eligibility
- 6 Months and older
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 4
- States / cities
- Port Saint Lucie, Florida • Louisville, Kentucky • San Antonio, Texas + 1 more
- Conditions
- Otitis Media With Effusion
- Interventions
- OTO-201, Sham
- Drug
- Lead sponsor
- Otonomy, Inc.
- Industry
- Eligibility
- 6 Months to 17 Years
- Enrollment
- 266 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Otitis Media
- Interventions
- OTO-201 (ciprofloxacin)
- Drug
- Lead sponsor
- Otonomy, Inc.
- Industry
- Eligibility
- 6 Months to 17 Years
- Enrollment
- 501 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Pre Operative Sedation, Mask Acceptance, Post Operative Delerium
- Interventions
- Combination of Dexmedetomidine with Midazolam
- Drug
- Lead sponsor
- Nemours Children's Clinic
- Other
- Eligibility
- 6 Months to 4 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014
- U.S. locations
- 1
- States / cities
- Wilmington, Delaware
- Conditions
- Otitis Media With Effusion
- Interventions
- Not listed
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 3 Years to 6 Years
- Enrollment
- 84 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2012
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Otorrhea, Otitis Media With Effusion in Children
- Interventions
- Otiprio, Ciprodex
- Drug
- Lead sponsor
- Boston Medical Center
- Other
- Eligibility
- 6 Months to 10 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Middle Ear Gas Exchange
- Interventions
- 6%CO2, 25%O2, balance N2, 6% CO2, 0%O2, balance N2, 20%CO2, 6%O2, balance N2, 0%CO2, 6%O2, balance N2, 6% CO2, 6%O2, balance N2, 6%CO2, 6%O2, 0%N2, balance argon
- Drug
- Lead sponsor
- Cuneyt M. Alper
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania