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ClinicalTrials.gov public records Last synced Oct 20, 2026, 12:24 AM EDT

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Showing 1–24 of 50 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Ultrafiltration Clear all
Completed Not applicable Interventional Results available

The Effect of the Hemobag® Ultrafiltration System on Blood Conservation and Coagulation After Cardiopulmonary Bypass

NCT01435304
View directory record Official record
Conditions
Blood Coagulation Disorders
Interventions
method of returning residual CPB blood ( Hemobag®)
Device
Lead sponsor
MaineHealth
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Oct 20, 2026, 12:24 AM EDT
Completed Not applicable Interventional Results available

Reducing Arrhythmia in Dialysis by Adjusting the Rx Electrolytes/Ultrafiltration, Study A

NCT03519347
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
Potassium Removal Maximization, Potassium Gradient Minimization, Alkalosis Avoidance, Acidosis avoidance, Point of Care Testing, Cardiac Monitor
Other · Diagnostic Test · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 85 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Oct 20, 2026, 12:24 AM EDT
Active, not recruiting Phase 2 Interventional

High vs. Standard Dose Influenza Vaccine in Lung Allograft Recipients

NCT05215327
View directory record Official record
Conditions
Immunization; Infection, Transplantation Infection, Influenza
Interventions
High Dose Quadrivalent Inactivated Influenza Vaccine, Standard Dose Quadrivalent Inactivated Influenza Vaccine
Biological
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
16 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 20, 2026, 12:24 AM EDT
Terminated Not applicable Interventional

A Feasibility Study on Ultrafiltration and Blood Volume Measurements

NCT04241718
View directory record Official record
Conditions
Acute Decompensated Heart Failure, Fluid Overload
Interventions
Aquadex FlexFlow System and BVA-100
Device
Lead sponsor
Nuwellis, Inc.
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Naperville, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 14, 2024 · Synced Oct 20, 2026, 12:24 AM EDT
Completed Not applicable Interventional

Hypertension in Hemodialysis

NCT00067665
View directory record Official record
Conditions
Hypertension, Left Ventricular Hypertrophy
Interventions
Ultrafiltration
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 28, 2011 · Synced Oct 20, 2026, 12:24 AM EDT
Active, not recruiting Not applicable Interventional

Directed Use of REmote Patient Management System AMia to Achieve Prescribed Dry Weight

NCT04002440
View directory record Official record
Conditions
Efficacy, Safety Issues
Interventions
AMIA with SHARESOURCE Connectivity Platform, HomeChoice PRO
Combination Product · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Chula Vista, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Oct 20, 2026, 12:24 AM EDT
Completed No phase listed Observational

Hemofilter Life Span, ECLS And/or CRRT

NCT04193865
View directory record Official record
Conditions
Kidney Diseases, Acute Injury of Kidney, Renal Failure, Renal Insufficiency, Neonatal Renal Disorder (Disorder)
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
0 Days to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Oct 20, 2026, 12:24 AM EDT
Not listed No phase listed Observational

Evaluation of the Optimal Transition Program

NCT04263233
View directory record Official record
Conditions
ESRD, Hemodialysis
Interventions
Analysis using descriptive statistics of patient clinical outcomes., Surveys with participants using validated survey tools., Evaluation of the program process including time, costs, referral rates, admission to the program and length of stay.
Other
Lead sponsor
Satellite Healthcare
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
3
States / cities
Oakland, California • Sacramento, California • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Oct 20, 2026, 12:24 AM EDT
Terminated Not applicable Interventional Results available

Using Intradialytic Blood Pressure Slopes to Guide Ultrafiltration

NCT03303391
View directory record Official record
Conditions
ESRD, Extracellular Fluid Alteration, Hypertension
Interventions
Intradialytic Blood Pressure Slope Based Ultrafiltration
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Oct 20, 2026, 12:24 AM EDT
Terminated Phase 2 Interventional Results available

Heart Failure and Peritoneal Ultrafiltration

NCT00368641
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Extraneal
Drug
Lead sponsor
Vantive Health LLC
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
5
States / cities
San Jose, California • Torrance, California • Denver, Colorado + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Oct 20, 2026, 12:24 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest

NCT01509040
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Standard Care, Low Volume Hemofiltration, High Volume Hemofiltration
Other · Device
Lead sponsor
University of Washington
Other
Eligibility
65 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 9, 2016 · Synced Oct 20, 2026, 12:24 AM EDT
Completed Not applicable Interventional Results available

Ultrafiltration Profiling and Outcomes Among Individuals on Maintenance Hemodialysis

NCT03301740
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
UF profiling during HD, Conventional HD
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 85 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
2
States / cities
Carrboro, North Carolina • Siler City, North Carolina
Source: ClinicalTrials.gov public record
Updated May 15, 2020 · Synced Oct 20, 2026, 12:24 AM EDT
Recruiting Phase 2 Interventional

High vs. Standard Dose Influenza Vaccines in Lung Transplant (Repeater)

NCT07192458
View directory record Official record
Conditions
Immunization; Infection|Transplantation Infection|Influenza, Influenza
Interventions
Fluzone High Dose Inactivated Influenza Vaccine, Fluzone Standard Dose Inactivated Influenza Vaccine
Biological
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Oct 20, 2026, 12:24 AM EDT
Terminated Not applicable Interventional Results available

Restrictive Versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury

NCT05306964
View directory record Official record
Conditions
Acute Kidney Injury, Fluid Overload, Hypotension, Dialysis; Complications, Critical Illness
Interventions
Restrictive UFnet Rate Strategy, Liberal UFnet Rate Strategy
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Rochester, Minnesota • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 29, 2025 · Synced Oct 20, 2026, 12:24 AM EDT
Terminated Not applicable Interventional

Pre Bypass Ultrafiltration (PBUF) in Children Requiring Cardiopulmonary Bypass

NCT03576534
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Use of prebypass ultrafiltration (PBUF)
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Day to 1 Year
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Oct 20, 2026, 12:24 AM EDT
Completed Early Phase 1 Interventional Results available

The Effects of Modified Ultrafiltration on Vancomycin Levels During Cardiopulmonary Bypass in Cardiac Surgery

NCT02051595
View directory record Official record
Conditions
Infection
Interventions
Vancomycin concentrations
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Oct 20, 2026, 12:24 AM EDT
Terminated Phase 2 Interventional Results available

Natrecor (Nesiritide) in Transplant-Eligible Management of Congestive Heart Failure-TMAC

NCT00338455
View directory record Official record
Conditions
Congestive Heart Failure, Cardiac Transplantation, Renal Insufficiency, Renal Failure
Interventions
Natrecor (nesiritide)+Standard Care+dobutamine or milrinone, Placebo+Standard Care+dobutamine or milrinone
Drug
Lead sponsor
Scios, Inc.
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
14
States / cities
Stanford, California • Tampa, Florida • Chicago, Illinois + 11 more
Source: ClinicalTrials.gov public record
Updated Dec 8, 2014 · Synced Oct 20, 2026, 12:24 AM EDT
Completed Not applicable Interventional Results available

Comparison Study of Daily Ultrafiltration and Twice-weekly Hemodialysis

NCT00825318
View directory record Official record
Conditions
End-stage Renal Disease
Interventions
Ultrafiltration
Procedure
Lead sponsor
Renal Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
3
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 26, 2014 · Synced Oct 20, 2026, 12:24 AM EDT
Completed Not applicable Interventional

Utilizing Blood Volume Measurements in the Treatment of Heart Failure Patients

NCT00861770
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Ultrafiltration, Ultrafiltration using BVM
Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 11, 2017 · Synced Oct 20, 2026, 12:24 AM EDT
Completed Phase 3 Interventional

Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients

NCT05456542
View directory record Official record
Conditions
Respiratory Failure
Interventions
Cuff Leak Test, Dexamethasone 4mg
Diagnostic Test · Drug
Lead sponsor
St. Joseph's Healthcare Hamilton
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 20, 2026, 12:24 AM EDT
Completed Not applicable Interventional

Optimizing Cardiovascular Health and Physical Function in Hemodialysis Patients Through Volume Control and Exercise

NCT02627066
View directory record Official record
Conditions
Renal Failure
Interventions
Volume Control, Volume Control + Exercise
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 90 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 2, 2018 · Synced Oct 20, 2026, 12:24 AM EDT
Completed Phase 4 Interventional

Tolvaptan/Ultrafiltration in the Treatment of Acute Heart Failure

NCT01863511
View directory record Official record
Conditions
Acute Decompensated Heart Failure
Interventions
loop diuretic, tolvaptan, ultrafiltration
Drug · Procedure
Lead sponsor
The Christ Hospital
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Oct 20, 2026, 12:24 AM EDT
Completed Not applicable Interventional

Pilot Study Using a Pulse Oximeter Derived Photo-plethysmographic Waveform to Guide Hemodialysis Ultrafiltration

NCT02264522
View directory record Official record
Conditions
Intradialytic Hypotension, Hypervolemia
Interventions
Place dialysis chair into position 3., Decrease dialysate temperature., Decrease ultrafiltration rate by 25%., Decrease ultrafiltration rate by 50%.
Other
Lead sponsor
Intelomed, Inc.
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 30, 2016 · Synced Oct 20, 2026, 12:24 AM EDT
Completed No phase listed Observational

Plasma Angiopoietin Levels in Children Following Cardiopulmonary Bypass

NCT01489475
View directory record Official record
Conditions
Congenital Heart Defects
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
Up to 18 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 26, 2015 · Synced Oct 20, 2026, 12:24 AM EDT