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ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:40 AM EDT

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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Ultrasonic instrumentation Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Clinical Outcomes Between GentleWave® and Biolase®

NCT05555043
View directory record Official record
Conditions
Endodontic Disease, Periapical Diseases, Periapical Periodontitis, Root Canal Infection
Interventions
Irrisafe ip, GentleWave System, Waterlase iPlus
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
14 Years to 99 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation

NCT05205616
View directory record Official record
Conditions
Surgical Complication, Paresthesia, Fracture, Nerve Injury, Nerve Entrapments, Mandibular Nerve Injuries, Mandibular Hypoplasia, Mandibular Retrognathism, Mandibular Hyperplasia, Mandibular Prognathism
Interventions
Sonopet ultrasonic saw, Reciprocating saw
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
Up to 45 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 20, 2026, 2:40 AM EDT
Not listed Not applicable Interventional

Focal US-guided Cryo-ablation Using DynaCAD / UroNAV Preplanning / Guidance of Intermediate Risk Prostate Cancer

NCT04656678
View directory record Official record
Conditions
Prostate Cancer, Prostate Disease
Interventions
Cryo-ablation Using DynaCAD / UroNAV preplanning / guidance
Device
Lead sponsor
Northwell Health
Other
Eligibility
45 Years and older · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
3
States / cities
Lake Success, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2024 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional Results available

Computer Assisted Instrument Guidance (CAIG) For Arterial Line Placement

NCT02584673
View directory record Official record
Conditions
Arterial and Midline Catheterization
Interventions
Computer Assisted Instrument Guidance (CAIG), which supplements existing ultrasound capabilities.
Device
Lead sponsor
Clear Guide Medical
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 14, 2017 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional

The Effect of Non-Surgical Periodontal Therapy on Glycemic Control and Bacterial Levels in a Mexican-American Population With Type 2 Diabetes

NCT01128374
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Periodontal Disease
Interventions
Periodontal Scaling and root planing
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Oct 20, 2026, 2:40 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers Results available

Harmonic Versus Electro Surgery in Lower Body Lift Procedures

NCT00522171
View directory record Official record
Conditions
Obesity
Interventions
The Harmonic™ ultrasonic scalpel
Device
Lead sponsor
Ethicon Endo-Surgery
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Coralville, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 9, 2009 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ultrasound and Near Infrared Imaging for Breast Cancer Diagnosis and Neoadjuvant Chemotherapy Monitoring

NCT02092636
View directory record Official record
Conditions
Breast Cancer
Interventions
NIR/US Diagnostic Group, NIR/US Neoadjuvant Chemotherapy Group, NIR/US Process Validation Group
Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 26, 2017 · Synced Oct 20, 2026, 2:40 AM EDT
Not listed Not applicable Interventional

Ultrasound-CT Fusion System for Interventional Radiology Procedures

NCT03226535
View directory record Official record
Conditions
CT Guided Biopsy, CT Guided Drain Placement Within the Abdomen or Pelvis, CT Guided Injection of Muscle or Nerve Within the Pelvis
Interventions
Ultrasound-CT Fusion
Device
Lead sponsor
Clear Guide Medical
Industry
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Oct 20, 2026, 2:40 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mapping of the Human Brainstem During Continence and Micturition: Noninvasive 7-T fMRI Study

NCT04846387
View directory record Official record
Conditions
Healthy
Interventions
Magnetic Resonance Imaging (MRI), Post-Void Residual, Uroflowmetry, Questionaire - AUA Symptom Score
Diagnostic Test · Behavioral
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Early Phase 1 Interventional

Ultrasound-Guided Photoacoustic Imaging for the Detection of Metastases in Inguinal Lymph Nodes

NCT04185337
View directory record Official record
Conditions
Malignant Neoplasm
Interventions
Fine-Needle Aspiration, Lymph Node Biopsy, Photoacoustic Imaging, Ultrasound, Multispectral optoacoustic tomography (MSOT) acuity instrument
Procedure · Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Oct 20, 2026, 2:40 AM EDT
Recruiting Not applicable Interventional

Bacterial Reduction After Supplementary Disinfection Procedures in Infected Root Canals

NCT06569329
View directory record Official record
Conditions
Dental Pulp Necroses
Interventions
GentleWave System Root Canal Therapy, EdgePro Laser Root Canal Therapy, The ProUltra Piezo Ultrasonic with EndoUltra Tips Root Canal Therapy
Device
Lead sponsor
Abhishek Parolia
Other
Eligibility
18 Years to 95 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 20, 2026, 2:40 AM EDT
Terminated Not applicable Interventional Results available

Three-dimensional Craniofacial Phenotyping of Patients With Difficult Airway

NCT01630694
View directory record Official record
Conditions
Failed or Difficult Intubation
Interventions
3D Laser Scanning of the Head, Measurements and Digital Photo's of the head, neck and Mouth, Ultrasound Exam of the Tongue
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 20, 2016 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional Results available

Erector Spinae Plane Blocks for Adolescent Idiopathic Scoliosis

NCT04500613
View directory record Official record
Conditions
Pain, Postoperative, Opioid Use, Recruitment
Interventions
Bilateral Erector Spinae Plane Block with bupivacaine and dexamethasone, No bilateral Erector Spinae Plane Block (no bupivacaine and no dexamethasone)
Procedure · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
10 Years to 19 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional

Standard Root Planing vs. Periodontal Structure Repair Device for Treatment of Pockets Caused by Periodontal Disease

NCT03671512
View directory record Official record
Conditions
Periodontal Diseases
Interventions
Periodontal Structure Repair (PSR), Standard Root Planing
Device
Lead sponsor
Periovance, Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
4
States / cities
Birmingham, Alabama • Cambridge, Massachusetts • Stony Brook, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Oct 20, 2026, 2:40 AM EDT
Active, not recruiting No phase listed Observational

3D Transcranial Ultrasound Brain Imaging (3D-TRUBI) Instrument for Point-of-Care Diagnosis of Intracranial Hemorrhages

NCT06780436
View directory record Official record
Conditions
Traumatic Brain Hemorrhage, Traumatic Brain Injury, Intracranial Hemorrhages, Ultrasound Exams, 3D SONOGRAPHY
Interventions
3D Transcranial Ultrasound Brain Imaging
Device
Lead sponsor
The Geneva Foundation
Other
Eligibility
18 Years to 89 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Oct 20, 2026, 2:40 AM EDT
Recruiting Not applicable Interventional

Surgeon-performed Ultrasound for Real-time Guidance In Oral Cancer Surgeries - A Multicenter Randomized Controlled Trial

NCT07203911
View directory record Official record
Conditions
Tongue Cancer, Oral Cancer, Squamous Cell Carcinoma of the Oral Cavity or Oropharynx
Interventions
Ultrasound imaging, Standard Treatment
Diagnostic Test · Other
Lead sponsor
Tobias Todsen
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
2
States / cities
Stanford, California • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional Results available

Computer Assisted Instrument Guidance (CAIG) for Orthopedic Peripheral Nerve Blocks

NCT02614222
View directory record Official record
Conditions
Peripheral Nerve Blocks
Interventions
Peripheral Nerve Blocks with CAIG
Device
Lead sponsor
Clear Guide Medical
Industry
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 7, 2017 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Harmonic™ vs. Electrocautery in Abdominoplasties

NCT00506740
View directory record Official record
Conditions
Skin and Fat Redundancy and Muscle Diastases
Interventions
Ultrasonic scalpel, monopolar electrosurgery generator and tip
Device
Lead sponsor
Ethicon Endo-Surgery
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
2
States / cities
Coralville, Iowa • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Oct 20, 2026, 2:40 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cost-Effectiveness of a Specialized Ultrasound Instrument to Diagnose Carotid Stenosis as a Way to Reduce the Risk of Stroke

NCT00417586
View directory record Official record
Conditions
Carotid Stenosis, Cerebrovascular Accident
Interventions
Specialized Doppler Ultrasound Instrument
Device
Lead sponsor
DVX, LLC
Industry
Eligibility
65 Years and older
Enrollment
984 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 11, 2013 · Synced Oct 20, 2026, 2:40 AM EDT
Not listed No phase listed Observational

Validation of Non-Invasive Intracranial Pressure (ICP) Monitoring Device

NCT03865576
View directory record Official record
Conditions
Intracranial Hypertension, Abnormality of Intracranial Pressure
Interventions
Non-invasive ICP measurement
Diagnostic Test
Lead sponsor
Boston Neurosciences
Industry
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
4
States / cities
Phoenix, Arizona • Atlanta, Georgia • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 7, 2019 · Synced Oct 20, 2026, 2:40 AM EDT
Terminated Not applicable Interventional Results available

Commensal Oral Microbiota in Head and Neck Cancer

NCT03843554
View directory record Official record
Conditions
Head and Neck Cancer, Oral Mucositis
Interventions
Standard of Care Oral Hygiene, Oral mucosal deterging and dental prophylaxis
Other · Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 20, 2026, 2:40 AM EDT
Active, not recruiting No phase listed Observational

Feasibility of Robotic Instrument Guidance System to Perform Safe Ultrasound-Guided Percutaneous Procedures During Routine Medical Procedures.

NCT07358351
View directory record Official record
Conditions
Percutaneous Access
Interventions
Mendaera Guidance System
Device
Lead sponsor
Mendaera, Inc
Industry
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Mateo, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 20, 2026, 2:40 AM EDT
Withdrawn Not applicable Interventional

A Clinical Phase II Study of the Materna Device to Shorten Delivery Time During Childbirth

NCT06698185
View directory record Official record
Conditions
Childbirth
Interventions
Materna Prep Device, Sham Control
Device
Lead sponsor
Materna Medical
Industry
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Oct 20, 2026, 2:40 AM EDT
Enrolling by invitation Not applicable Interventional

Endoscopic Gastroenterostomy Versus Surgical Gastrojejunostomy

NCT06567691
View directory record Official record
Conditions
Malignant Gastric Outlet Obstruction
Interventions
EUS Gastrojejunostomy, Surgical Gastrojejunostomy, Gastric Outlet Obstruction Scoring System (GOOSS)
Procedure · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Oct 20, 2026, 2:40 AM EDT