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Showing 1–24 of 310 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Usual Pain Management Care Clear all
Withdrawn Not applicable Interventional

Comprehensive Opioid Management in Patient Aligned Care Teams

NCT01737073
View directory record Official record
Conditions
Chronic Pain
Interventions
IVR self-management, Opioid monitoring, Enhanced usual care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
2
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Sep 22, 2026, 6:55 PM EDT
Completed Not applicable Interventional

The Kaia Hip and Knee Pain Intervention for Self-management of the Pain in Patients With Osteoarthritis.

NCT04615377
View directory record Official record
Conditions
Knee Osteoarthritis, Hip Osteoarthritis
Interventions
Kaia hip and knee pain application, Treatment as usual
Behavioral · Other
Lead sponsor
Kaia Health Software
Industry
Eligibility
22 Years to 75 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 15, 2022 · Synced Sep 22, 2026, 6:55 PM EDT
Completed Phase 2 Interventional Results available

HOPE Consortium Trial to Reduce Pain and Opioid Use in Hemodialysis

NCT04571619
View directory record Official record
Conditions
End Stage Renal Disease, Chronic Pain, Opioid Dependence
Interventions
Pain Coping Skills Training (PCST), Buprenorphine
Behavioral · Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
643 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
16
States / cities
West Haven, Connecticut • Chicago, Illinois • Boston, Massachusetts + 11 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced Sep 22, 2026, 6:55 PM EDT
Completed Phase 2 Interventional Results available

Digital Therapeutic for Chronic Pain Feasibility Study

NCT06000007
View directory record Official record
Conditions
Chronic Pain
Interventions
2Morrow Chronic Pain Self-Management Program - digital therapeutic mobile app, Treatment as usual
Device · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 22, 2026, 6:55 PM EDT
Completed Not applicable Interventional

Collaborative Targeted Case Management in Improving Functional Status in Patients With Stage III-IV Cancer

NCT01721343
View directory record Official record
Conditions
Cognitive/Functional Effects, Malignant Neoplasm, Pain
Interventions
telephone-based intervention, case management, management of therapy complications, physical therapy, questionnaire administration, quality-of-life assessment, assessment of therapy complications, educational intervention
Behavioral · Other · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
516 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 22, 2026, 6:55 PM EDT
Terminated Not applicable Interventional

Mindfulness to Improve Functional Outcomes in Patients With Fibromyalgia or Central Sensitization

NCT03693274
View directory record Official record
Conditions
Chronic Pain, Fibromyalgia, Central Sensitisation
Interventions
BreathAware for Pain Management
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
30 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 26, 2020 · Synced Sep 22, 2026, 6:55 PM EDT
Recruiting Not applicable Interventional

Improving Health for Older Adults With Pain Through Engagement

NCT06119698
View directory record Official record
Conditions
Chronic Pain, Musculoskeletal Pain
Interventions
GetActive+
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
55 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Sep 22, 2026, 6:55 PM EDT
Completed Not applicable Interventional

Acceptance and Commitment Therapy for Chronic Pain in Integrated Primary Care

NCT04978961
View directory record Official record
Conditions
Chronic Pain
Interventions
Focused Acceptance & Commitment Therapy (FACT), Enhanced Treatment as Usual (ETAU)
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 99 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 26, 2021 · Synced Sep 22, 2026, 6:55 PM EDT
Completed Not applicable Interventional Results available

EMPOWER: Randomized Trial of Online Chronic Pain Management Program to Reduce Reliance on Opioid Analgesic Medications

NCT03308188
View directory record Official record
Conditions
Chronic Pain
Interventions
E-health program
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
25 Years to 80 Years
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Durham, North Carolina • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 22, 2026, 6:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Honey Used as Adjunct Therapy to Tylenol for Post-Op Tonsillectomy Patients

NCT03931395
View directory record Official record
Conditions
Tonsillectomy
Interventions
Honey, Standard of Care
Dietary Supplement · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
2 Years to 17 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Sep 22, 2026, 6:55 PM EDT
Withdrawn Not applicable Interventional

Here's the Buzz: Evaluating Pediatric Post Op Pain and Nausea Following Tonsillectomy Surgery

NCT04910919
View directory record Official record
Conditions
Tonsillectomy
Interventions
Honey, Standard of Care
Dietary Supplement · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
5 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 6, 2022 · Synced Sep 22, 2026, 6:55 PM EDT
Not yet recruiting Phase 3 Interventional

An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service

NCT07296770
View directory record Official record
Conditions
Postsurgical Pain Management, Postsurgical Pain, Chronic, Opioid Use After Surgery
Interventions
TPS-Select, Pharmacologic Pain Management, Interventional Pain Procedures, Psychological Management and Pain Education, Physical Therapy
Device · Drug · Procedure + 1 more
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 22, 2026, 6:55 PM EDT
Withdrawn Not applicable Interventional

The Dementia Symptom Management at Home Program

NCT02482623
View directory record Official record
Conditions
Dementia
Interventions
Dementia Symptom Management at Home Program
Behavioral
Lead sponsor
New York University
Other
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Sep 22, 2026, 6:55 PM EDT
Completed Not applicable Interventional Results available

Literacy-Adapted Psychosocial Treatments for Chronic Pain --- "Learning About Mastering/My Pain"

NCT01967342
View directory record Official record
Conditions
Chronic Pain, Pain, Widespread Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury
Interventions
Pain Ed, CBT for Pain, Usual Care
Behavioral · Other
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
19 Years and older
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
3
States / cities
Tuscaloosa, Alabama • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Sep 22, 2026, 6:55 PM EDT
Active, not recruiting Phase 3 Interventional

Comparing Radiation Therapy to Usual Treatment for Patients With High-Risk Bone Metastases That Are Not Causing Pain, PREEMPT Trial

NCT06745024
View directory record Official record
Conditions
Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Solid Neoplasm
Interventions
Best Practice, Biospecimen Collection, Bone Metastases Treatment, Computed Tomography, Conventional Radiotherapy, Magnetic Resonance Imaging, Patient Observation, Questionnaire Administration, Stereotactic Body Radiation Therapy
Other · Procedure · Radiation
Lead sponsor
NRG Oncology
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2034
U.S. locations
624
States / cities
Fairbanks, Alaska • Gilbert, Arizona • Phoenix, Arizona + 450 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 22, 2026, 6:55 PM EDT
Terminated Not applicable Interventional Results available

Does Optimized General Anesthesia Care Reduce Postoperative Delirium?

NCT02604459
View directory record Official record
Conditions
Hip Fractures, Anesthesia, Delirium
Interventions
cerebral oximeter (Fore-Sight), depth of anesthesia monitor (BIS), BP management, General anesthesia, propofol, fentanyl, sevoflurane
Device · Procedure · Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
65 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Sep 22, 2026, 6:55 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Enhanced Recovery at Cesarean Birth to Improve Postoperative Outcomes and Reduce Postoperative Length of Stay

NCT02956616
View directory record Official record
Conditions
Cesarean Section
Interventions
ketorolac, Chewing Gum, Enhanced Recovery Protocol
Drug · Other · Procedure
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2019 · Synced Sep 22, 2026, 6:55 PM EDT
Completed Not applicable Interventional Results available

C-RFA of Residual Limb Neuroma

NCT04538417
View directory record Official record
Conditions
Phantom Limb Pain, Neuroma Amputation
Interventions
Cooled Radiofrequency Ablation
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Sep 22, 2026, 6:55 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Feasibility and Acceptability of Music Therapy for Chronic Pain

NCT05426941
View directory record Official record
Conditions
Chronic Pain
Interventions
Music Imagery, Music Listening
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Sep 22, 2026, 6:55 PM EDT
Terminated Not applicable Interventional Results available

Expanding Access to Home-Based Palliative Care

NCT03128060
View directory record Official record
Conditions
Cancer, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
Interventions
Home-based palliative care, Enhanced usual care
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 22, 2026, 6:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Acute Post-Operative Dental Pain Management Using New Health Information Technology

NCT03881891
View directory record Official record
Conditions
Pain, Postoperative, Complication, Postoperative
Interventions
Follow-app intervention arm
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
1,525 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
San Francisco, California • Hillsboro, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 3, 2022 · Synced Sep 22, 2026, 6:55 PM EDT
Active, not recruiting Phase 4 Interventional

Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment

NCT06367387
View directory record Official record
Conditions
Opioid Use Disorder, Chronic Pain
Interventions
Patient-Oriented Dosing (POD), Pain Self-Management (PSM), Usual Care, Standard Buprenorphine Dosing Condition
Drug · Behavioral
Lead sponsor
Erin Winstanley
Other
Eligibility
18 Years and older
Enrollment
273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
13
States / cities
Baltimore, Maryland • Dundalk, Maryland • Hagerstown, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 22, 2026, 6:55 PM EDT
Recruiting Not applicable Interventional

A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD

NCT05081596
View directory record Official record
Conditions
Depression, Pain, Cognitive Impairment
Interventions
PATH-Pain
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 22, 2026, 6:55 PM EDT
Completed Not applicable Interventional

Automated Hovering for Joint Replacement Surgery

NCT03435549
View directory record Official record
Conditions
Joint Disease
Interventions
Remote monitoring, Remote monitoring plus goal setting and social support
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2019 · Synced Sep 22, 2026, 6:55 PM EDT