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ClinicalTrials.gov public records Last synced Sep 30, 2026, 10:50 AM EDT

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Showing 25–46 of 46 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Usual PrEP care Clear all
Completed Not applicable Interventional Accepts healthy volunteers

A Latino MSM Focused Pre-Exposure Prophylaxis Uptake Intervention

NCT05434390
View directory record Official record
Conditions
HIV
Interventions
Estoy PrEParado/ I am PrEPared intervention, Usual Care
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Male only
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 30, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Leveraging the Emergency Department to Engage African American Women in HIV Pre-Exposure Prophylaxis

NCT03930654
View directory record Official record
Conditions
HIV Infections
Interventions
iPrEP, Usual Care
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Sep 30, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile Enhanced Prevention Support for People Leaving Jail

NCT04036396
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Diseases, Bacterial, Hepatitis C, Substance Use Disorders
Interventions
Mobile Enhanced Prevention Support, Usual Care plus Customized Referrals
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 49 Years · Male only
Enrollment
233 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
3
States / cities
Los Angeles, California • Santa Fe Springs, California
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Sep 30, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Women's Initiative Supporting Health Increasing Healthcare Access

NCT02964845
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
WISH with CHW and referral to HFM, Enhanced Treatment as Usual
Behavioral · Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older · Female only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 2, 2019 · Synced Sep 30, 2026, 10:50 AM EDT
Recruiting Not applicable Interventional

Hepatitis C Pharmacist, Physician, Patient Navigator Collaborative Care Model in Permanent Supportive Housing

NCT07667101
View directory record Official record
Conditions
HEPATITIS C (HCV)
Interventions
PPP-CCM
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 30, 2026, 10:50 AM EDT
Completed Not applicable Interventional Results available

TAKE Steps: Motivational Interviewing to Prevent STIs

NCT05215262
View directory record Official record
Conditions
Self Efficacy, HIV Prevention, STI Prevention
Interventions
Treat Act Know Engage (T.A.K.E.) Steps, Standard or Care
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
13 Years to 19 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
5
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Sep 30, 2026, 10:50 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Linking Youth to Pre-Exposure Prophylaxis (PrEP) Services

NCT07438041
View directory record Official record
Conditions
HIV, PrEP, PrEP Adherence
Interventions
LYPS, Enhanced Standard of Care
Other
Lead sponsor
Westat
Other
Eligibility
13 Years to 24 Years
Enrollment
272 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
4
States / cities
San Francisco, California • Atlanta, Georgia • Baltimore, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 30, 2026, 10:50 AM EDT
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Naltrexone for Overdose Prevention

NCT06633900
View directory record Official record
Conditions
Overdose Accidental
Interventions
IM naltrexone, Usual Care
Drug · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 30, 2026, 10:50 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Pilot Study to Evaluate Skin Swabbing With Chlorhexidine to Prevent Skin And Soft Tissue Infections Among People Who Inject Drugs

NCT06733506
View directory record Official record
Conditions
Opioid Use Disorder, Injection Drug Use, Skin and Soft Tissue Infections (SSTIs)
Interventions
Chlorhexidine gluconate, Isopropyl Alcohol 70% Topical Application Solution, Skin Prep Before Injecting Recreational/Street Drugs
Drug · Behavioral
Lead sponsor
Gabriel John Culbert
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Sep 30, 2026, 10:50 AM EDT
Completed Not applicable Interventional Results available

North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2

NCT03548779
View directory record Official record
Conditions
Epilepsy; Seizure, Neuromuscular Diseases, Brain Malformation, Intellectual Disability, Autism Spectrum Disorder, Hypotonia, Inborn Errors of Metabolism, Movement Disorders, Genetic Disease, Development Delay, Chromosome Abnormality, Hearing Loss, Dysmorphic Features, Skeletal Dysplasia, Congenital Abnormality, Microcephaly, Macrocephaly
Interventions
Pre-visit prep, usual care + exome seq
Behavioral · Diagnostic Test
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
0 Years and older
Enrollment
548 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
3
States / cities
Asheville, North Carolina • Chapel Hill, North Carolina • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Sep 30, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

eSTEP: An Integrated mHealth Intervention to Engage High-risk Individuals Along the Full PrEP Care Continuum

NCT06159582
View directory record Official record
Conditions
Pre-Exposure Prophylaxis (PrEP)
Interventions
eSTEP, Usual Care
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older · Male only
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 30, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The OPENS Trial: Offering Women PrEP (Aim 2)

NCT05619497
View directory record Official record
Conditions
Human Immunodeficiency Virus, Human Immunodeficiency Virus Transmission, Sexually Transmitted Diseases
Interventions
Clinic-wide Trainings, Clinic-wide Trainings and HIV Prevention Decision Support Tool (DST), Standard Care with the HIV Prevention Decision Support Tool (DST)
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 45 Years
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Sep 30, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PrEP Optimization Among Women to Enhance Retention and Uptake

NCT05626452
View directory record Official record
Conditions
PrEP Uptake
Interventions
PrEP Education, Provider training, EMR Optimization, PrEP Navigation, Provider Audit and Feedback
Behavioral · Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
724 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 30, 2026, 10:50 AM EDT
Recruiting Not applicable Interventional

PrEP and MOUD Rapid Access for Persons Who Inject Drugs: The CHORUS+ Study

NCT05769218
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
CHORUS+, Standard of care
Behavioral · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
284 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 30, 2026, 10:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

NCT05624931
View directory record Official record
Conditions
Depression, Posttraumatic Stress Disorder, Pregnancy Related, Medication Adherence
Interventions
Brief CBT-Based Intervention, Enhanced Treatment as Usual
Behavioral · Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
15 Years and older · Female only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Sep 30, 2026, 10:50 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

A Comparative Effectiveness Demonstration Project for Linkage and Retention in PrEP Care for Men Who Have Sex With Men

NCT03442192
View directory record Official record
Conditions
Adherence, Patient
Interventions
PrEP Care Anywhere Services
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 9, 2022 · Synced Sep 30, 2026, 10:50 AM EDT
Recruiting Not applicable Interventional

Assessing the Use of MY-RIDE, a Just-in-time Adaptive Intervention, to Improve HIV Prevention and Substance Use in Youth Experiencing Homelessness

NCT06074354
View directory record Official record
Conditions
HIV Infections
Interventions
Attention-control group, MY-RIDE group
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 25 Years
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 30, 2026, 10:50 AM EDT
Recruiting Not applicable Interventional

RESTORE Study R61 Phase: Recovery and Engagement for Stimulant Users on Re-entry

NCT07136363
View directory record Official record
Conditions
HIV, Stimulant Use Disorder, Justice Involved Populations, HIV Prevention
Interventions
DynamiCare, Patient Navigation (PN)
Device · Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
New Haven, Connecticut • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 30, 2026, 10:50 AM EDT
Active, not recruiting Not applicable Interventional

A Simple Intervention to Increase Persistence on PrEP in MSM to Improve Decision Making

NCT06476847
View directory record Official record
Conditions
HIV Infections
Interventions
PrEP persistence
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years and older · Male only
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Sep 30, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Leveraging Electronic Health Record Data in a Risk Prediction Model to Increase HIV PrEP Intake in Primary Care

NCT05991869
View directory record Official record
Conditions
Pre-Exposure Prophylaxis
Interventions
Point-of-care decision support intervention
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Sep 30, 2026, 10:50 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans

NCT06766331
View directory record Official record
Conditions
Opioid Use Disorder, HIV, Hepatitis C Virus, Gonorrhea, Chlamydia, Syphilis, Sexually Transmitted Infection, Integrated Care, Medications for Opioid Use Disorder
Interventions
Integrated care
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2028 – 2029
U.S. locations
1
States / cities
Northport, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Sep 30, 2026, 10:50 AM EDT
Completed Not applicable Interventional Results available

An Electronic Health Record-based Approach to Increase PrEP Knowledge and Uptake: the EMC2 PrEP Strategy

NCT05709860
View directory record Official record
Conditions
HIV Infections, Electronic Health Record, Primary Health Care
Interventions
EMC2 PrEP Educational Tool, Discrete Scheduling of a Dedicated PrEP Visit
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Sep 30, 2026, 10:50 AM EDT