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Showing 1–24 of 57 matching trials from the live ClinicalTrials.gov search.
Conditions
Sleep Deprivation, Critical Illness, Sleep-Wake Disorders, Bundle Care, Implementation Science, Delirium
Interventions
Nighttime noise & light reduction, Clustering patient-care interactions, Non-pharmacologic sleep aids, Daytime light exposure, Encourage out-of-bed activity, Medication management to support nighttime sleep
Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
62,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
7
States / cities
La Jolla, California • San Francisco, California • Orlando, Florida + 4 more
Conditions
Insomnia
Interventions
Internet-based Self-help Insomnia Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
West Haven, Connecticut
Conditions
Chronic Insomnia
Interventions
COAST-enhanced CBTI, Military Treatment Facility Insomnia Care As Usual
Behavioral
Lead sponsor
Noctem, LLC
Industry
Eligibility
18 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lakewood, Washington
Recruiting Phase 1Phase 2 Interventional

Mindfulness Meditation for Insomnia

NCT06972303
Conditions
Sleep Initiation and Maintenance Disorders, Insomnia, Insomnia Chronic, Mindfulness, Telemedicine
Interventions
Instructed bedtime app-guided mindfulness meditation, Uninstructed app-guided mindfulness meditation, Sleep hygiene education
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

RELAXaHEAD for Headache Patients (Phase II)

NCT05466682
Conditions
Migraine, Headache, Multiple Sclerosis, Insomnia
Interventions
Smartphone-Based Progressive Muscle Relaxation Therapy (PMR), Monitored Usual Care (MUC)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Conditions
Concussion, Brain, Sleep Disorder
Interventions
Brief Sleep Intervention
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
13 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Insomnia, Chronic Pain
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Interdisciplinary Pain Rehabilitation Program (IPRP)
Behavioral
Lead sponsor
Mary Free Bed Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Grand Rapids, Michigan
Conditions
Insomnia Disorder
Interventions
Virtual Coaching
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 100 Years
Enrollment
244 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
5
States / cities
West Haven, Connecticut • Augusta, Maine • Leeds, Massachusetts + 2 more
Completed Not applicable Interventional Results available

Research on Improving Sleep During Pregnancy

NCT05017974
Conditions
Sleep, Pregnancy Related
Interventions
Mindfulness-Based Stress Reduction plus Prenatal Sleep supplement, Treatment as Usual
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Conditions
Insomnia, Depression
Interventions
CBT for Insomnia (CBT-I), Sleep Hygiene (SH)
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
12 Years to 19 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Portland, Oregon
Enrolling by invitation Not applicable Interventional

SHADES Mechanistic Trial

NCT06041581
Conditions
Insomnia, Insomnia Chronic, Insomnia, Primary, Sleep Disturbance, Sleep Disorder, Cardiovascular Diseases, Heart Diseases, Coronary Artery Disease, Stroke, Autonomic Dysfunction, Systemic Inflammatory Response, Metabolic Disease
Interventions
Sleep Healthy Using The Internet (SHUTi), Telephonic CBT-I, Face-to-Face CBT-I, Active Control: Sleep Education/Hygiene, Symptom Monitoring, and Usual Primary Care
Behavioral · Other
Lead sponsor
Indiana University
Other
Eligibility
40 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Results available

Research on Expecting Moms and Sleep Therapy

NCT02805998
Conditions
Insomnia
Interventions
Web-based CBT-I, Treatment as Usual
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
San Francisco, California
Conditions
Insomnia
Interventions
Digital cognitive behavioral therapy for insomnia (CBT-I) program, Minimally Enhanced Usual Care (mEUC), Somryst (culturally adapted)
Behavioral · Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Conditions
Peripheral Neuropathy, Chemotherapy-induced Peripheral Neuropathy
Interventions
Acupuncture, Sham Acupuncture, Usual Care Group, questionnaires
Procedure · Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
Commack, New York • New York, New York
Conditions
PTSD
Interventions
NAP, CPT, ERRT, Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
VA Eastern Kansas
Federal
Eligibility
18 Years to 99 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Leavenworth, Kansas
Conditions
Advanced Lung Cancer, Physical Function
Interventions
PROMOTE Digital Health App Intervention, Enhanced Usual Care
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Insomnia Disorder, Cognitive Functioning
Interventions
CBTi: Stimulus Control Core, CBTi: Sleep Restriction Core, CBTi: Sleep Compression Core
Behavioral
Lead sponsor
Idaho State University
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Pocatello, Idaho
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of the Heart to Heart Yoga Program

NCT05778747
Conditions
Heart Failure, Caregiver Burden, Depression, Anxiety, Stress
Interventions
Heart to Heart Yoga
Other
Lead sponsor
Misook L. Chung
Other
Eligibility
18 Years to 99 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Sleep Wake Disorders, Sleep Disturbance, Sleep-Related Impairment
Interventions
Transdiagnostic Sleep and Circadian Intervention (TranS-C), adapted for cardiac rehabilitation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Acupressure for Fatigue in Systemic Lupus Erythematosus

NCT03200548
Conditions
Fatigue, Lupus Erythematosus, Systemic, Pain, Chronic, Quality of Life, Sleep
Interventions
Relaxing acupressure plus usual care, Usual care, Stimulating acupressure plus usual care, Sham acupressure plus usual care
Behavioral
Lead sponsor
Suzanna Zick
Other
Eligibility
18 Years and older · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Terminated Not applicable Interventional Accepts healthy volunteers

Integrative Cardiac Health Project Cognitive-Behavior Therapy for Insomnia

NCT02779023
Conditions
Insomnia, Cardiovascular Risk Factor
Interventions
Cognitive-Behavior Therapy for Insomnia (CBT-I)
Behavioral
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Insomnia, Fibromyalgia
Interventions
CBT
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Diabetes Type 2, Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia, Usual care for diabetes management, Usual care for treatment of insomnia
Behavioral · Other
Lead sponsor
Tulane University
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Zachary, Louisiana