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Showing 1–17 of 17 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: V.A.C. Therapy Clear all
Terminated Not applicable Interventional

Evaluation of V.A.C. VERAFLO CLEANSE CHOICE™ Dressing Using Normal Saline to Promote Increased Healthy Wound Bed Tissue

NCT04026334
View directory record Official record
Conditions
Wound, Wound Heal, Wounds and Injuries, Granulation Tissue, Negative-pressure Wound Therapy
Interventions
V.A.C. VERAFLO CLEANSE CHOICE™ dressing with Normal Saline
Device
Lead sponsor
3M
Industry
Eligibility
22 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 31, 2022 · Synced Sep 7, 2026, 7:10 PM EDT
Recruiting Not applicable Interventional

Evaluation of a Switchable Acrylic Adhesive Drape for Safer Removal in Negative Pressure Wound Therapy Applications.

NCT06717308
View directory record Official record
Conditions
Frequency and Type of Medical Adhesive-Related Skin Injury, NPWT Drape Seal Effectiveness Rate (or Leak Incidence Rate), Clinician Acceptability of New NPWT Drape, Patient Drop-out Rate From Prescribed NPWT Treatment, Pain Assessment During Medical Adhesive Drape Removal
Interventions
Comfort Release® NPWT drape
Device
Lead sponsor
Global Biomedical Technologies, LLC
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Los Angeles, California • Torrance, California • Miami, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 7, 2026, 7:10 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation Wound Complications

NCT03773575
View directory record Official record
Conditions
Amputation, Amputation; Postoperative, Sequelae, Wound Dehiscence, Seroma, Wound Infection, Surgical, Lymph Leakage
Interventions
PREVENA™ PEEL & PLACE™ Dressing Kit
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Valhalla, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 7, 2026, 7:10 PM EDT
Withdrawn Not applicable Interventional

Incisional Wound Vac in Obese Patients

NCT00789659
View directory record Official record
Conditions
Wound Infection, Postoperative Complication
Interventions
Negative pressure dressing
Other
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 9, 2017 · Synced Sep 7, 2026, 7:10 PM EDT
Completed Not applicable Interventional Results available

Evaluating the Ease of Use of a VAC GranuFoam Bridge Dressing on Diabetic Foot Ulcers Receiving VAC Negative Pressure Wound Therapy

NCT00847730
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
V.A.C. Negative Pressure Wound Therapy System
Device
Lead sponsor
KCI USA, Inc
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
6
States / cities
New Haven, Connecticut • South Miami, Florida • Bethlehem, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Sep 7, 2026, 7:10 PM EDT
Terminated Not applicable Interventional Results available

VeraFlo With Prontosan® and Wound and Fracture Healing.

NCT02621073
View directory record Official record
Conditions
Infection
Interventions
VeraFlo with Prontosan, V.A.C Ulta System
Drug · Device
Lead sponsor
Brett Crist
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Sep 7, 2026, 7:10 PM EDT
Completed Phase 4 Interventional Results available

ABRA Abdominal Closure System in Open Abdomen Management

NCT00754156
View directory record Official record
Conditions
Open Abdomen
Interventions
ABRA Abdominal Closure System, V.A.C. Therapy, KCI ABThera
Device
Lead sponsor
Anna Rockich
Other
Eligibility
18 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 2, 2017 · Synced Sep 7, 2026, 7:10 PM EDT
Completed Not applicable Interventional Results available

A Pilot RCT of Veraflo With Prontosan vs VAC in Wounds Requiring Operative Debridement

NCT01867580
View directory record Official record
Conditions
Wounds and Injuries
Interventions
V.A.C.Ulta with Prontosan instillation, V.A.C.Ulta without instillation
Device
Lead sponsor
KCI USA, Inc
Industry
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Miami, Florida • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2024 · Synced Sep 7, 2026, 7:10 PM EDT
Terminated Not applicable Interventional

Coupling Negative Pressure Wound Therapy With Instillation

NCT04677166
View directory record Official record
Conditions
Wound, Ulcer, Burns
Interventions
Negative pressure wound therapy coupled with instillation, Standard Negative Pressure Wound Therapy
Device
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 90 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Sep 7, 2026, 7:10 PM EDT
Recruiting Phase 4 Interventional

NPWTi on Closure of Chronic Pressure Sores

NCT05598398
View directory record Official record
Conditions
Pressure Sore
Interventions
V.A.C.Ulta™ Negative Pressure Wound Therapy System, Standard of Care (Wet-to-dry dressings)
Device · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 7, 2026, 7:10 PM EDT
Completed Not applicable Interventional Results available

Vacuum-Assisted Dressings (V-AD) in the Management of Open Chest Wounds

NCT02803164
View directory record Official record
Conditions
Open Chest Wounds
Interventions
Wound Vacuum-assisted dressing, Control group
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Sep 7, 2026, 7:10 PM EDT
Withdrawn Not applicable Interventional

VAC NPWT KCI Dressing Study

NCT01366105
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
V.A.C. by K.C.I.
Device
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 3, 2013 · Synced Sep 7, 2026, 7:10 PM EDT
Completed Not applicable Interventional Results available

V.A.C. VeraFlo™ Instillation Therapy vs V.A.C. Ulta™ Therapy on Biofilm in Chronically Infected Wounds

NCT02009501
View directory record Official record
Conditions
Lower Extremity Wound Infected, Venous Stasis Ulcers
Interventions
VAC VeraFlo with Dakins Instillation, VAC Ulta Therapy
Device
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 26, 2018 · Synced Sep 7, 2026, 7:10 PM EDT
Completed Not applicable Interventional

Impact of V.A.C. Veraflo Therapy in Wounds Requiring Debridement Within an Orthopedic Practice

NCT02266771
View directory record Official record
Conditions
Wounds and Injuries
Interventions
NPWT with Instillation, NPWT
Device
Lead sponsor
LifeBridge Health
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 14, 2018 · Synced Sep 7, 2026, 7:10 PM EDT
Terminated Not applicable Interventional Results available

Negative Pressure Wound Therapy With Instillation of Saline Solution Versus Collagenase Ointment in Full-thickness Wounds

NCT03722485
View directory record Official record
Conditions
Wounds and Injuries, Wound Healing, Granulation Tissue
Interventions
Negative Pressure Therapy w/ instillation and dwell (NPWTi-d), Collagenase Ointment
Device · Biological
Lead sponsor
KCI USA, Inc
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
10
States / cities
Phoenix, Arizona • Tucson, Arizona • Washington D.C., District of Columbia + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Sep 7, 2026, 7:10 PM EDT
Completed Phase 2 Interventional

Efficacy Study of a Bioelectric Dressing Used With Negative Pressure Wound Therapy to Treat Diabetic and Pressure Ulcers

NCT01022216
View directory record Official record
Conditions
Wound Healing
Interventions
Procellera™ Wound Dressing with V.A.C.® Therapy, V.A.C.® Therapy
Device
Lead sponsor
Vomaris Innovations
Industry
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Feb 21, 2012 · Synced Sep 7, 2026, 7:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Study Evaluating the Safety and Efficacy of the 3M™ V.A.C. Peel and Place Dressing

NCT06625385
View directory record Official record
Conditions
Wound
Interventions
3M™ V.A.C.® Peel and Place Dressing
Device
Lead sponsor
Solventum US LLC
Industry
Eligibility
22 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
3
States / cities
Indianapolis, Indiana • St Louis, Missouri • Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 7, 2026, 7:10 PM EDT