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ClinicalTrials.gov public records Last synced Sep 10, 2026, 9:42 PM EDT

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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: VAD Clear all
Not listed Early Phase 1 Interventional

Pumps for Kids, Infants, and Neonates

NCT02954497
View directory record Official record
Conditions
Pediatric Heart Failure
Interventions
Surgical placement of the Jarvik 2015 VAD, Surgical Placement of Jarvik 2015 VAD
Device · Procedure
Lead sponsor
Carelon Research
Other
Eligibility
Not listed
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
7
States / cities
Palo Alto, California • Atlanta, Georgia • Boston, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Sep 10, 2026, 9:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ventricular Assist Device (VAD) Infection Prevention Survey

NCT03843021
View directory record Official record
Conditions
Heart Failure, Healthcare Associated Infection, Ventricular Assist Device
Interventions
VAD Infection Prevention Survey
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Sep 10, 2026, 9:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Silver Lining in the VAD Sky

NCT05163392
View directory record Official record
Conditions
LVAD (Left Ventricular Assist Device) Driveline Infection
Interventions
Silverlon, Control
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 10, 2026, 9:42 PM EDT
Completed Phase 2 Interventional Results available

UARK 89-001 Phase II Study of Intensive "TOTAL THERAPY" For Untreated or Minimally Treated Patients With Multiple Myeloma

NCT00580372
View directory record Official record
Conditions
Multiple Myeloma
Interventions
VAD, High-Dose cyclophosphamide, Hemopoietic stem cell procurement, EDAP, Autologous Hemopoietic Stem Cell Transplant 1, Autologous Hemopoietic Stem Cell Transplant 2, Maintenance
Drug · Procedure
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2015
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 19, 2016 · Synced Sep 10, 2026, 9:42 PM EDT
Recruiting Not applicable Interventional

Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment

NCT03891160
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
3D model of heart
Other
Lead sponsor
Columbia University
Other
Eligibility
Not listed
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
5
States / cities
Gainesville, Florida • Atlanta, Georgia • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Sep 10, 2026, 9:42 PM EDT
Withdrawn Not applicable Interventional

The Destination Therapy Evaluation for Failing Fontan Study

NCT01149603
View directory record Official record
Conditions
Failing Fontan Physiology, Failing Fontan, Single-ventricle, Single-ventricle Fontan, Single-ventricle Physiology
Interventions
HeartMate II Ventricular Assist Device
Device
Lead sponsor
Timothy Icenogle, MD
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Sep 20, 2017 · Synced Sep 10, 2026, 9:42 PM EDT
Completed Not applicable Interventional Results available

Self-Management App for Patients With Left-Ventricular Assist Devices

NCT03049748
View directory record Official record
Conditions
Heart Failure
Interventions
Mobile phone app (VAD Care App), Usual LVAD Care
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
3
States / cities
St Louis, Missouri • Lincoln, Nebraska • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 15, 2020 · Synced Sep 10, 2026, 9:42 PM EDT
Recruiting No phase listed Observational

Pharmacokinetics of Bivalirudin for Pediatric Anticoagulation

NCT03532399
View directory record Official record
Conditions
Drug Effect
Interventions
Bivalirudin
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Sep 10, 2026, 9:42 PM EDT
Not listed No phase listed Observational

Registry to Monitor Berlin Heart EXCOR® Pediatric VAD as a Bridge to Cardiac Transplantation.

NCT03701997
View directory record Official record
Conditions
Ventricular Dysfunction, Ventricular Dysfunction, Left, Ventricular Dysfunction, Right
Interventions
EXCOR Pediatric
Device
Lead sponsor
Berlin Heart, Inc
Industry
Eligibility
1 Day to 21 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 9, 2018 · Synced Sep 10, 2026, 9:42 PM EDT
Completed Phase 3 Interventional Results available

Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor

NCT00945009
View directory record Official record
Conditions
Adult Kidney Wilms Tumor, Beckwith-Wiedemann Syndrome, Childhood Kidney Wilms Tumor, Diffuse Hyperplastic Perilobar Nephroblastomatosis, Rhabdoid Tumor of the Kidney, Stage I Kidney Wilms Tumor, Stage II Kidney Wilms Tumor, Stage III Kidney Wilms Tumor, Stage IV Kidney Wilms Tumor, Stage V Kidney Wilms Tumor
Interventions
Dactinomycin, Doxorubicin Hydrochloride, Radiation Therapy, Therapeutic Conventional Surgery, Vincristine Sulfate
Biological · Drug · Radiation + 1 more
Lead sponsor
Children's Oncology Group
Network
Eligibility
Up to 29 Years
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2026
U.S. locations
146
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 111 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 10, 2026, 9:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of Simulation to Improve VAD Self-management

NCT03073005
View directory record Official record
Conditions
Heart Failure
Interventions
Simulation-based Mastery Learning (SBML)
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 9, 2021 · Synced Sep 10, 2026, 9:42 PM EDT
Completed Not applicable Interventional Results available

Ventricular Assist Device Anti-Factor Xa (VAD ANTIX) Monitoring Study: a Prospective Randomized Feasibility Trial

NCT03143569
View directory record Official record
Conditions
Left Sided Heart Failure, Left Ventricular Assist Device, Anticoagulant Therapy, Gastro Intestinal Bleeding, Thrombosis, LVAD, Anti-factor Xa, aPTT, Heparin
Interventions
aPTT guided heparin management, Anti-factor Xa guided heparin management
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Sep 10, 2026, 9:42 PM EDT
Recruiting Not applicable Interventional

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

NCT06310031
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Heart Failure
Interventions
BrioVAD System, HeartMate 3
Device
Lead sponsor
BrioHealth Solutions, Inc.
Industry
Eligibility
18 Years to 100 Years
Enrollment
780 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
47
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 32 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 10, 2026, 9:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Cotton as a Dampener for Vibration Anesthetic Device

NCT06916468
View directory record Official record
Conditions
Patient Care
Interventions
VAD with Cotton Dampener, Vibratory Anesthetic Device (VAD)
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 10, 2026, 9:42 PM EDT
Recruiting No phase listed Observational

Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease

NCT01099982
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
13 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2030
U.S. locations
3
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 10, 2026, 9:42 PM EDT
Completed Not applicable Interventional

AKI Prevention and Early Intervention in Patients Undergoing VAD Placement

NCT03236831
View directory record Official record
Conditions
Kidney Injury
Interventions
Clinical Recommendations
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 9, 2019 · Synced Sep 10, 2026, 9:42 PM EDT
Not yet recruiting Not applicable Interventional

Palliative Care Intervention to Improve Health Related Quality of Life for Patients on Long-Term LVAD Support

NCT07445932
View directory record Official record
Conditions
Advanced Heart Failure, Mechanical Circulatory Support, Left Ventricular Assist Device, Palliative Care
Interventions
Palliative care intervention
Behavioral
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Sep 10, 2026, 9:42 PM EDT
Terminated Not applicable Interventional

Clinical Trial to Evaluate the the ReliantHeart HeartAssist 5® VAD System in Patients Awaiting Heart Transplantation

NCT02205411
View directory record Official record
Conditions
Heart Failure, Cardiac Failure, Congestive Heart Failure, Heart Failure, Left-sided
Interventions
HeartAssist 5® VAD System, Control VAD
Device
Lead sponsor
ReliantHeart Inc.
Industry
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
14
States / cities
San Francisco, California • Stanford, California • Coral Gables, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Sep 10, 2026, 9:42 PM EDT
Completed Early Phase 1 Interventional

Infusion of Panobinostat (MTX110) Into the Fourth Ventricle in Children and Adults with Recurrent Medulloblastoma

NCT04315064
View directory record Official record
Conditions
Medulloblastoma
Interventions
Treatment with MTX110
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
1 Year to 80 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Sep 10, 2026, 9:42 PM EDT
Completed No phase listed Observational

A Study to Determine the Signs and Symptoms That Impact Daily Life of Participants With Irregular Sleep-Wake Rhythm Disorder

NCT04300569
View directory record Official record
Conditions
Irregular Sleep Wake Rhythm Disorder
Interventions
Non-interventional
Other
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
6
States / cities
Costa Mesa, California • San Diego, California • Miami, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2020 · Synced Sep 10, 2026, 9:42 PM EDT
Completed Not applicable Interventional Results available

Assess Safety and Probable Benefit of the EXCOR® Pediatric Ventricular Assist Device

NCT00583661
View directory record Official record
Conditions
Heart Failure, Cardiomyopathies
Interventions
EXCOR Pediatric
Device
Lead sponsor
Berlin Heart, Inc
Industry
Eligibility
1 Day to 16 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
15
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Palo Alto, California + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2013 · Synced Sep 10, 2026, 9:42 PM EDT
Completed No phase listed Observational

Understanding and Addressing Variations in HAIs After Durable Ventricular Assist Device Therapy

NCT03749434
View directory record Official record
Conditions
Healthcare-Associated Infections
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
34,958 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Sep 10, 2026, 9:42 PM EDT
Completed Not applicable Interventional Results available

Effects of Exercise in Combination With Epoetin Alfa

NCT00577096
View directory record Official record
Conditions
Multiple Myeloma
Interventions
Epoetin Alfa, Exercise, Autologous Peripheral Blood Stem Cell Transplantation, Red Blood Cell Transfusion, Thalidomide, Heparin, Low-Molecular-Weight, Platelet Transfusion, Melphalan, Total Therapy II
Drug · Behavioral · Biological
Lead sponsor
University of Arkansas
Other
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 5, 2015 · Synced Sep 10, 2026, 9:42 PM EDT
Completed No phase listed Observational

Implantable Cardioverter Defibrillator (ICD) Function During Ventricular Assist Device (VAD) Implantation

NCT01576562
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 7, 2017 · Synced Sep 10, 2026, 9:42 PM EDT