- Conditions
- Post-COVID-19 Syndrome, Postural Tachycardia Syndrome, Dysautonomia
- Interventions
- Non-invasive vagus nerve stimulation, Sham Intervention
- Device
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
Search Results
Search by objective public record fields.
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All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–24
of 48
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Depression, Epilepsy
- Interventions
- Vagal nerve stimulant
- Device
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 2
- States / cities
- Minneapolis, Minnesota • Rochester, Minnesota
- Conditions
- Tinnitus
- Interventions
- VNS Treatment, VNS Control
- Device
- Lead sponsor
- MicroTransponder Inc.
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 3
- States / cities
- Iowa City, Iowa • Buffalo, New York • Dallas, Texas
- Conditions
- Alcohol Withdrawal, Alcohol Use Disorder
- Interventions
- Transcutaneous Nerve Stimulation, Sham Stimulation
- Device
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 18 Years to 65 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Manhasset, New York
- Conditions
- Epilepsy, Sudden Cardiac Death
- Interventions
- A change or titration in the current or frequency settings of the VNS therapy system.
- Other
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Chronic Migraine
- Interventions
- GammaCore Active Device, GammaCore Sham Device
- Device
- Lead sponsor
- ElectroCore INC
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 59 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 6
- States / cities
- San Francisco, California • Ann Arbor, Michigan • Springfield, Missouri + 3 more
- Conditions
- Major Depressive Disorder
- Interventions
- vagus nerve stimulation (VNS)
- Device
- Lead sponsor
- Cyberonics, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 266 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2005
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Parkinson Disease
- Interventions
- taVNS, Exercise
- Device · Behavioral
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 35 Years to 80 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 2
- States / cities
- Birmingham, Alabama
- Conditions
- Functional Gastrointestinal Disorders, Hypermobile Ehlers-Danlos Syndrome, Postural Orthostatic Tachycardia Syndrome, Autonomic Nervous System Disease, Autonomic Nervous System Imbalance
- Interventions
- Percutaneous vagal nerve stimulation (pVNS) device, Acoustic vagal nerve stimulation (aVNS) treatment
- Device · Other
- Lead sponsor
- Medical College of Wisconsin
- Other
- Eligibility
- 10 Years to 18 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Neuromodulation
- Interventions
- Auricular Vagal Nerve Stimulation
- Device
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Traumatic Brain Injury
- Interventions
- Nurosym taVNS, Nurosym (sham)
- Device
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 2
- States / cities
- San Antonio, Texas
- Conditions
- Traumatic Brain Injury (TBI) Patients
- Interventions
- Transcutaneous vagus nerve stimulation for attention in veterans with TBI, Soterix Medical Vagus Nerve Stimulation mini-CT
- Other · Device
- Lead sponsor
- Baylor College of Medicine
- Other
- Eligibility
- 25 Years to 64 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Irritable Bowel Syndrome (IBS-C)
- Interventions
- Transcutaneous Auricular Vagus Nerve Stimulation (ta-VNS), Sham Transcutaneous Auricular Vagus Nerve Stimulation
- Device
- Lead sponsor
- West Virginia University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Morgantown, West Virginia
- Conditions
- Pain, Postoperative, Opioid Use, Lumbar Spine Injury
- Interventions
- Sparrow Ascent Transcutaneous Auricular Neurostimulation (tAN), Sham Control Device
- Device
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- PTSD, Post Traumatic Stress Disorder
- Interventions
- Active VNS stimulation, Sham VNS stimulation
- Device
- Lead sponsor
- The University of Texas at Dallas
- Other
- Eligibility
- 22 Years to 79 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 3
- States / cities
- Austin, Texas • Dallas, Texas • Richardson, Texas
- Conditions
- Substance-Related Disorders, Substance Use Disorders, Substance Abuse, Intravenous, Substance Withdrawal, Substance Abuse, Opioid-use Disorder, Opioid Use Disorder, Severe, Opioid Use
- Interventions
- Non invasive VN stimulation (nVNS), Oxygen (15-O) Water, Sham Stimulation
- Device · Drug
- Lead sponsor
- Emory University
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Idiopathic Nephrotic Syndrome, Frequently Relapsing Nephrotic Syndrome
- Interventions
- Transcutaneous Auricular Vagus Nerve (taVNS) stimulation
- Device
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 2 Years to 21 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- New Hyde Park, New York
- Conditions
- Epilepsy, Depressive Disorder
- Interventions
- Vagus nerve stimulation device: acute and chronic administration of investigational vagus nerve stimulation parameters
- Device
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 144 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 5
- States / cities
- Stanford, California • Minneapolis, Minnesota • St Louis, Missouri + 2 more
- Conditions
- Multiple Sclerosis
- Interventions
- Remotely Supervised Transcranial Direct Current Stimulation (RS - tDCS), Remotely Supervised Transcutaneous Auricular Vagus Nerve Stimulation (RS - taVNS), Remotely Supervised Transcutaneous Cervical Vagus Nerve Stimulation (RS - tcVNS)
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 25 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Epilepsy, Seizures, Drug Resistant Epilepsy
- Interventions
- Vagus Nerve Stimulation (VNS) Therapy
- Device
- Lead sponsor
- LivaNova
- Industry
- Eligibility
- Not listed
- Enrollment
- 827 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2024
- U.S. locations
- 19
- States / cities
- Grand Junction, Colorado • Washington D.C., District of Columbia • Orlando, Florida + 15 more
- Conditions
- Pain, Migraine
- Interventions
- VNS device, Inactive device
- Device
- Lead sponsor
- Benjamin Natelson
- Other
- Eligibility
- 42 Years to 80 Years
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 4
- States / cities
- East Orange, New Jersey • New York, New York
- Conditions
- Nephrotic Syndrome in Children, Minimal Change Disease, Focal Segmental Glomerulosclerosis
- Interventions
- trascutaneous auricular vagus nerve stimulation, Sham device
- Device
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 3 Years to 17 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 2
- States / cities
- New Hyde Park, New York • Philadelphia, Pennsylvania
- Conditions
- Crohn Disease
- Interventions
- Vagal Nerve Stimulator
- Device
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- PTSD, Post Traumatic Stress Disorder PTSD, PTSD - Post Traumatic Stress Disorder, Post Traumatic Stress Disorder, Post Traumatic Stress Disorders, Post-traumatic Stress Disorder (PTSD), Post-Traumatic Stress Disorder, PTSD
- Interventions
- non-invasive vagus nerve stimulation
- Device
- Lead sponsor
- Acacia Clinics
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Sunnyvale, California