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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Vacuum-assisted closure (VAC) therapy Clear all
Terminated Phase 1 Interventional Accepts healthy volunteers

Vacuum Assisted Closure for Cesarean Section

NCT02390401
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Vacuum-assisted closure, Standard sterile dressing
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
166 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
4
States / cities
Lebanon, New Hampshire • Nashua, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 21, 2018 · Synced Sep 28, 2026, 2:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Wound Vac Bandage Comparison After Spinal Fusion

NCT03000010
View directory record Official record
Conditions
Neuromuscular Scoliosis
Interventions
Incisional Wound Vac, Standard Bandage
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
0 Years to 17 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 27, 2021 · Synced Sep 28, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

Comparison of Two Methods of Negative Pressure Wound Therapy

NCT00724750
View directory record Official record
Conditions
Acute Wounds From Trauma, Dehiscence or Surgical Complications
Interventions
Gauze suction (G-SUC), Vacuum Assisted Closure Device (VAC)
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 18, 2015 · Synced Sep 28, 2026, 2:55 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

The Effect of Nitroglycerin Ointment, Fluorescent Angiography, and Incisional Negative Pressure Wound Therapy on Mastectomy Skin Flap Perfusion-Related Problems

NCT03716050
View directory record Official record
Conditions
Perfusion; Complications
Interventions
Nitroglycerin, Negative Pressure Wound Therapy/ Wound VAC, Fluorescent Angiography with indocyanine-green (not to exceed 5mg/kg), No treatment
Drug · Device · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Sep 28, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

Vacuum Assisted Closure as a Treatment for Open Fractures

NCT00582361
View directory record Official record
Conditions
Orthopaedic Traumatic Open Fractures
Interventions
Standard Wound Dressing, VAC
Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 13, 2013 · Synced Sep 28, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries

NCT00582998
View directory record Official record
Conditions
Fracture of Calcaneus, Pilon or Tibial Plateau
Interventions
Standard Wound Dressing, Vacuum Assisted Closure Device
Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Sep 28, 2026, 2:55 PM EDT
Completed Not applicable Interventional

Vacuum Assisted Closure as a Treatment for Draining Hematomas

NCT00582179
View directory record Official record
Conditions
Draining Hematoma
Interventions
Standard Pressure Dressing, VAC
Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 30, 2013 · Synced Sep 28, 2026, 2:55 PM EDT
Withdrawn Not applicable Interventional

Incisional Wound Vac in Obese Patients

NCT00789659
View directory record Official record
Conditions
Wound Infection, Postoperative Complication
Interventions
Negative pressure dressing
Other
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 9, 2017 · Synced Sep 28, 2026, 2:55 PM EDT
Withdrawn Not applicable Interventional

VAC NPWT KCI Dressing Study

NCT01366105
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
V.A.C. by K.C.I.
Device
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 3, 2013 · Synced Sep 28, 2026, 2:55 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: Vacuum Assisted Closure (VAC) and Gauze Suction (GSUC)

NCT00952120
View directory record Official record
Conditions
Wound Healing
Interventions
GSUC, VAC
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Sep 28, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

Randomized, Controlled Multicenter Trial of Vacuum Assisted Closure Therapy™ in Diabetic Foot Ulcers

NCT00432965
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Moist Wound Therapy, VAC Therapy
Device
Lead sponsor
KCI USA, Inc
Industry
Eligibility
18 Years and older
Enrollment
335 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
24
States / cities
Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 17 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Sep 28, 2026, 2:55 PM EDT
Withdrawn Not applicable Interventional

A Comparison of Incisional Negative-Pressure Wound Therapy Versus Conventional Dressings Following Abdominal Surgery

NCT02534116
View directory record Official record
Conditions
Abdominal Reconstruction
Interventions
Vacuum-assisted closure (VAC) therapy, Gauze dressing
Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 15, 2018 · Synced Sep 28, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

Role of Vacuum Assisted Closure (VAC) Device in Postoperative Management of Pelvic and Acetabular Fractures

NCT00635479
View directory record Official record
Conditions
Pelvic Fractures, Acetabular Fractures, Hip Fractures
Interventions
VAC device, Gauze dressing
Device · Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 10, 2017 · Synced Sep 28, 2026, 2:55 PM EDT
Withdrawn Phase 2 Interventional

Open Label Trial of NanoDOX Hydrogel in Orthopedic Trauma Wounds With and Without Vacuum Assisted Closure Therapy

NCT01518491
View directory record Official record
Conditions
Orthopedic Trauma Wounds
Interventions
NanoDOX Hydrogel, VAC Alone
Drug · Other
Lead sponsor
NanoSHIFT LLC
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
2
States / cities
Bethesda, Maryland • Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 22, 2017 · Synced Sep 28, 2026, 2:55 PM EDT
Withdrawn Phase 4 Interventional

Comparative Effectiveness Study of MIST Therapy Versus Negative Pressure Wound Therapy

NCT01200563
View directory record Official record
Conditions
Wounds
Interventions
MIST Therapy, Vacuum Assisted Closure, MIST Therapy and Negative Pressure Wound Therapy
Device
Lead sponsor
Celleration, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 14, 2014 · Synced Sep 28, 2026, 2:55 PM EDT