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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.

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Filters: Intervention: Vaginal Health Placebo Control Clear all

Conditions: Healthy, HIV
Interventions: Tenofovir disoproxil fumarate intravaginal ring, Placebo intravaginal ring (IVR); Drug
Lead sponsor: Marla Keller; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Vaginal Health
Interventions: estriol, Placebo; Drug
Lead sponsor: Gynuity Health Projects; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 104 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 2
States / cities: Los Angeles, California • Chicago, Illinois

Conditions: Bacterial Vaginosis, Yeast Infection
Interventions: Prebiotic + Probiotic Supplement, Active Placebo Supplement, Excipient Placebo Supplement; Dietary Supplement
Lead sponsor: Happy V; Industry
Eligibility: 25 Years and older · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Menopause
Interventions: Probiotic, Placebo; Dietary Supplement · Other
Lead sponsor: Lallemand Health Solutions; Industry
Eligibility: 40 Years to 59 Years · Female only
Enrollment: 144 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 5
States / cities: Lake Worth, Florida • Port Saint Lucie, Florida • Atlanta, Georgia + 2 more

Conditions: Pelvic Organ Prolapse
Interventions: pudendal block, no pudendal block; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Pelvic Organ Prolapse
Interventions: Solifenacin, Placebo, Ring pessary with support, Cooper Surgical, Trumbell, CT Ref # MXPRS03 non-latex; Drug · Device
Lead sponsor: Hartford Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: BACTERIAL VAGINOSIS
Interventions: RIFAXIMIN VAGINAL TABLET 25 MG, RIFAXIMIN VAGINAL TABLET 100 MG, PLACEBO VAGINAL TABLET, METROGEL VAGINAL; Drug
Lead sponsor: Alfasigma S.p.A.; Industry
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 392 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Pelvic Floor Disorders
Interventions: Postmenopausal, topical vaginal estrogen cream, Placebo Comparator: Postmenopausal, topical placebo cream; Drug
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: 21 Years to 70 Years · Female only
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2023
U.S. locations: 1
States / cities: Galveston, Texas

Conditions: Perimenopause, Menopausal Symptoms, Menopause-Related Quality of Life, Microbiome
Interventions: Supplement, Placebo; Dietary Supplement · Other
Lead sponsor: Able Biolabs, LLC; Other
Eligibility: 35 Years to 55 Years · Female only
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Obesity & Overweight, Perimenopausal Women, Prebiotics, Inulin, Muscle, Skeletal, Cardiovascular Diseases (CVD), Microbiota, Gastrointestinal Microbiome, Dietary Fiber, Women Health, Vascular Health, Insulin Resistance
Interventions: Inulin, Maltodextrin (Placebo); Dietary Supplement
Lead sponsor: George Washington University; Other
Eligibility: 40 Years to 55 Years · Female only
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Allergic Diseases, Asthma
Interventions: Vaginal seeding, Placebo Seeding, Standard care, Post-seeding Care; Drug · Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 2
States / cities: New York, New York

Conditions: Atrophy of Vagina, Menopause, Dyspareunia (Female)
Interventions: Vagifem, Replens, Placebo tablet, Placebo gel; Drug · Device · Other
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 45 Years to 70 Years · Female only
Enrollment: 302 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 2
States / cities: Minneapolis, Minnesota • Seattle, Washington

Conditions: Vaginal Personal Care
Interventions: VM-02, Commercial Oral Probiotic Competitor, VM-02 Placebo; Other · Dietary Supplement
Lead sponsor: Seed Health; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Venice, California

Conditions: Vaginal Health
Interventions: Vaginal Health Placebo Control, Vaginal Health Active VV-01; Dietary Supplement
Lead sponsor: Radicle Science; Industry
Eligibility: 21 Years to 60 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Del Mar, California

Conditions: Vaginal Dysbiosis, Vaginal Disease, Molecular-bacterial Vaginosis
Interventions: Probiotic Group, Placebo Group; Dietary Supplement
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 45 Years · Male only
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Brooklyn, New York

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Safety and Pharmacokinetics (PK) of a Polyurethane Tenofovir Disoproxil Fumarate (TDF) Vaginal Ring (TDF IVR-002)

Topical Estriol for Vaginal Health

A Study to Evaluate the Effects of a Prebiotic and Probiotic Supplement to Provide Relief From Symptoms Associated With Bacterial Vaginosis and Yeast Infections.

The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health

Use of Pre-Emptive Pudendal Nerve Block for Pelvic Reconstructive Surgery

Clinical Trial of Solifenacin Versus Placebo Plus Pessary for Women With Vaginal Prolapse

Efficacy and Safety Study of Rifaximin Vaginal Tablets in Bacterial Vaginosis

Hormonal Status on Blood Flow and Tissue in Pelvic Organ Prolapse

A Study to Evaluate the Efficacy of a Postbiotic Supplement on Menopausal Symptoms in Premenopausal Women

Prebiotic Inulin for Late-Reproductive Individuals

Vaginal Microbiome Exposure and Immune Responses in C-section Infants

The Vaginal Health Trial

Randomized, Double-blind, Placebo-controlled Trial Investigating the Role of a Personal Care Product on Vaginal Health

A Trial to Assess the Pharmacokinetics and Pharmacodynamics of a Novel Synbiotic Oral Supplement for Vaginal Health

Feasibility of an Oral Intervention for Sexual Health in Transgender Men