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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Vaginal Surgery Clear all
Terminated Phase 4 Interventional Results available

Liposomal Bupivacaine in Vaginal Hysterectomy

NCT03907033
View directory record Official record
Conditions
Vaginal Hysterectomy
Interventions
Liposomal bupivacaine, Bupivacaine Hydrochloride
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 14, 2021 · Synced Sep 20, 2026, 9:34 PM EDT
Not listed Not applicable Interventional

The Effect of Preemptive Levator Ani Injections on Pain After Pelvic Reconstructive Surgery

NCT04428320
View directory record Official record
Conditions
Pelvic Floor Prolapse, Surgery, Pain, Postoperative
Interventions
Pelvic floor injection
Procedure
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 10, 2020 · Synced Sep 20, 2026, 9:34 PM EDT
Not listed Phase 4 Interventional

Surgical Intervention With DermaPure vs Native Tissue in Pelvic Organ Prolapse

NCT03939715
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
DermaPure®, native tissue
Biological · Procedure
Lead sponsor
Colorado Pelvic Floor Consultants
Industry
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Sep 20, 2026, 9:34 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES

NCT05688943
View directory record Official record
Conditions
Anesthesia, Tubal Ligation
Interventions
Spinal Anesthesia, General Anesthesia
Procedure
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
21 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 20, 2026, 9:34 PM EDT
Terminated Phase 4 Interventional

Clinical Trial of Solifenacin Versus Placebo Plus Pessary for Women With Vaginal Prolapse

NCT01092624
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Solifenacin, Placebo, Ring pessary with support, Cooper Surgical, Trumbell, CT Ref # MXPRS03 non-latex
Drug · Device
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 3, 2011 · Synced Sep 20, 2026, 9:34 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ultrasound Evaluation for Improving Patient Selection in vNOTES

NCT05623514
View directory record Official record
Conditions
Surgery
Interventions
Trans-vaginal ultrasound
Combination Product
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 13, 2024 · Synced Sep 20, 2026, 9:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Flourish Vaginal Care System to Establish Neovaginal Microbiome

NCT05372770
View directory record Official record
Conditions
Neovaginal Microbiome
Interventions
Flourish Vaginal Care system
Device
Lead sponsor
Vaginal Biome Science
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New Hope, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Sep 20, 2026, 9:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physical Therapy on Quality of Life and Function Following Vaginal Surgery Reconstructive Surgery

NCT01403701
View directory record Official record
Conditions
Quality of Life, Pelvic Floor Distress and Impact Scores, Sexual Function Scores
Interventions
Physical therapy
Behavioral
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2014 · Synced Sep 20, 2026, 9:34 PM EDT
Terminated Not applicable Interventional

SCP vs HUSLS for Pelvic Organ Prolapse Repair

NCT02800512
View directory record Official record
Conditions
Pelvic Organ Prolapse, Cystocele, Rectocele, Enterocele
Interventions
Robotic sacrocolpopexy, high uterosacral ligament suspension
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 20, 2026, 9:34 PM EDT
Terminated Phase 4 Interventional

Study of the Elevate Apical and Posterior Prolapse Repair System Compared to Native Tissue Repair for Pelvic Organ Prolapse

NCT02123992
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Elevate Apical and Posterior, Native Tissue Repair for pelvic organ prolapse
Device · Procedure
Lead sponsor
ASTORA Women's Health
Industry
Eligibility
18 Years and older · Female only
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
23
States / cities
Tucson, Arizona • Newport Beach, California • New Haven, Connecticut + 20 more
Source: ClinicalTrials.gov public record
Updated Sep 6, 2016 · Synced Sep 20, 2026, 9:34 PM EDT
Recruiting Phase 3 Interventional

Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial

NCT05379153
View directory record Official record
Conditions
Vaginal Atrophy, Breast Carcinoma
Interventions
Laser Therapy, Sham Intervention, Questionnaire Administration, Quality of Life Assessment
Device · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
22 Years and older · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Ann Arbor, Michigan • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 20, 2026, 9:34 PM EDT
Completed Not applicable Interventional Results available

Minimally Invasive Burch Colposuspension to Reduce Occult Stress Incontinence

NCT03841513
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urinary Incontinence,Stress, Urinary Incontinence, Urge, Bowel Dysfunction, Sexual Dysfunction
Interventions
Laparoscopic Burch Colposuspension
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Chicago, Illinois • Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 20, 2026, 9:34 PM EDT
Completed Not applicable Interventional

Optimal Timing of Cord Clamping in Preterm Pregnancy Following Vaginal or Cesarean Delivery

NCT01766908
View directory record Official record
Conditions
Preterm Birth
Interventions
Clamp cord 20, 40 or 60 seconds following vaginal or cesarean delivery
Other
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Dec 15, 2014 · Synced Sep 20, 2026, 9:34 PM EDT
Active, not recruiting Not applicable Interventional

Impact of Preop Video on Patient Anxiety

NCT05633901
View directory record Official record
Conditions
Prolapse, Vaginal, Prolapse, Uterine, Prolapse; Female
Interventions
Educational Video, Standard Counseling
Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Sep 20, 2026, 9:34 PM EDT
Completed Not applicable Interventional Results available

Study of Uterine Prolapse Procedures - Randomized Trial

NCT01802281
View directory record Official record
Conditions
Uterovaginal Prolapse
Interventions
Uterosacral ligament suspension, Uphold® LITE
Procedure
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2025
U.S. locations
8
States / cities
Birmingham, Alabama • La Jolla, California • Albuquerque, New Mexico + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 20, 2026, 9:34 PM EDT
Recruiting Phase 3 Interventional

Topical Estrogen: Brief Intervention to Improve Postoperative Experience for Transgender Men Undergoing Hysterectomy

NCT06969326
View directory record Official record
Conditions
Postoperative Bleeding, Gender Dysphoria, Hysterectomy
Interventions
Use of topical estradiol, No intervention
Drug · Other
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced Sep 20, 2026, 9:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of a Risk Calculator on Patient Satisfaction With the Decision for Midurethral Sling During Prolapse Surgery

NCT02111642
View directory record Official record
Conditions
Pelvic Organ Prolapse, Stress Urinary Incontinence, Satisfaction
Interventions
Online risk calculator
Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 19, 2022 · Synced Sep 20, 2026, 9:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pudendal Nerve Block in Vaginal Surgery

NCT04198714
View directory record Official record
Conditions
Nerve Block, Pain, Postoperative, Pelvic Floor Disorders, Pelvic Organ Prolapse, Pudendal Neuralgia, Surgery
Interventions
Pudendal block
Procedure
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 11, 2024 · Synced Sep 20, 2026, 9:34 PM EDT
Completed Phase 2 Interventional

18 Month Follow Up of Preterm Infants Enrolled in the Cord Clamping Study

NCT01426698
View directory record Official record
Conditions
Developmental Delay
Interventions
delayed cord clamping
Procedure
Lead sponsor
University of Rhode Island
Other
Eligibility
24 Weeks to 31 Weeks
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 4, 2014 · Synced Sep 20, 2026, 9:34 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Transgender Post-reassignment Urogynecologic Measures and Perceptions

NCT03293771
View directory record Official record
Conditions
Gender Identity Disorder of Adult, Voiding Disorders, Sexual Dysfunction
Interventions
Focus group interviews, Questionnaire packet
Other · Diagnostic Test
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Male only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2019 · Synced Sep 20, 2026, 9:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Surgeon Core-strengthening Program as a Modifier for Exertion Associated With Vaginal Surgery

NCT06525701
View directory record Official record
Conditions
Musculoskeletal Pain, Musculoskeletal Injury
Interventions
Execise Group, Control Group
Other
Lead sponsor
Loyola University
Other
Eligibility
Not listed
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Sep 20, 2026, 9:34 PM EDT
Completed Phase 3 Interventional

Study Comparing Tension-free Vaginal Tape With the Monarc Procedure for Stress Urinary Incontinence

NCT00475839
View directory record Official record
Conditions
Stress Urinary Incontinence
Interventions
Tension-free Vaginal Tape, Monarc sub-fascial hammock
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
3
States / cities
Baltimore, Maryland • Cincinnati, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 9, 2013 · Synced Sep 20, 2026, 9:34 PM EDT
Terminated Not applicable Interventional Results available

Prospective Randomized Controlled Trial of Obstructed Defecation Surgery

NCT05747027
View directory record Official record
Conditions
Obstructed Defecation, Pelvic Organ Prolapse
Interventions
Laparoscopic abdominal ventral rectopexy, Transvaginal sacrospinous rectopexy
Procedure
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Skokie, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Sep 20, 2026, 9:34 PM EDT
Completed Phase 2 Interventional Results available

Vaginal Cuff Brachytherapy Followed by Chemotherapy in Patients With Endometrioid Cancer

NCT00542490
View directory record Official record
Conditions
Endometrial Cancer, Papillary Serous, Clear Cell Endometrial Cancer
Interventions
Vaginal Cuff Brachytherapy
Radiation
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older · Female only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Sep 20, 2026, 9:34 PM EDT