Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 6, 2026, 9:58 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 305 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Vagus nerve stimulation Clear all
Completed Not applicable Interventional Results available

VNS During Rehabilitation for Improved Upper Limb Motor Function After Stroke

NCT02243020
View directory record Official record
Conditions
Stroke, Upper Limb Deficits
Interventions
Vagus Nerve Stimulation (VNS)
Device
Lead sponsor
MicroTransponder Inc.
Industry
Eligibility
30 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
3
States / cities
Minneapolis, Minnesota • Dallas, Texas • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Sep 6, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

Acupuncture for Low-Dose Opioid for TKA Replacement

NCT04084288
View directory record Official record
Conditions
Knee Osteoarthritis, Pain, Postoperative, Acupuncture
Interventions
Acupuncture, Peripheral Nerve Stimulator
Other · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 70 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Sep 6, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

Vagal Nerve Stimulation for Post COVID Fatigue

NCT05445427
View directory record Official record
Conditions
Post COVID Syndrome, Fatigue, Headache
Interventions
vagal nerve stimulator
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 6, 2026, 9:58 PM EDT
Active, not recruiting Not applicable Interventional

Non-Invasive Median Nerve Stimulation to Attenuate Atrial Tachyarrhythmias After Catheter Ablation for Atrial Fibrillation

NCT06748157
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
CardiaCare RR2, Sham Device
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 6, 2026, 9:58 PM EDT
Recruiting Not applicable Interventional

Evaluating Noninvasive Brain Stimulation for TMD Pain: A Feasibility Study

NCT07517172
View directory record Official record
Conditions
Temporomandibular Disorder
Interventions
Transcutaneous Auricular Neurostimulation, Sham Stimulation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 6, 2026, 9:58 PM EDT
Withdrawn Not applicable Interventional

Investigating Accelerated Learning in Tinnitus Participants Implanted With Vagus Nerve Stimulation

NCT03143842
View directory record Official record
Conditions
VNS Implanted Tinnitus Patients
Interventions
Vagus Nerve Stimulation
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Jan 27, 2022 · Synced Sep 6, 2026, 9:58 PM EDT
Terminated Not applicable Interventional

Transcutaneous Autonomic Modulation in Thoracic Surgery

NCT02783157
View directory record Official record
Conditions
Atrial Fibrillation, Postoperative, Postoperative Complications, Inflammation
Interventions
Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS), Sham LLVNS
Device
Lead sponsor
Duke University
Other
Eligibility
40 Years to 90 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 5, 2020 · Synced Sep 6, 2026, 9:58 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Anti-inflammatory Actions of Osteopathic Manipulative Treatment

NCT04177264
View directory record Official record
Conditions
Inflammation
Interventions
Occipito-Atlantal Decompression (OA DC), Sham Occipito-Atlantal Decompression (Sham OA DC), Splenic Lymphatic Pump Technique (SpLPT), Sham Splenic Lymphatic Pump Technique (Sham SpLPT), Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Sham Transcutaneous Auricular Vagus Nerve Stimulation (Sham taVNS)
Procedure · Device
Lead sponsor
Burrell College of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Las Cruces, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 6, 2026, 9:58 PM EDT
Recruiting Not applicable Interventional

Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia

NCT07191119
View directory record Official record
Conditions
Survivor of Childhood Cancer, Insomnia, Acute Lymphoblastic Leukemia (ALL)
Interventions
Soterix tVNS device, Soterix tVNS device (sham programmed), Sleep Quality, Neurocognitive and mental health outcomes
Device · Behavioral
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
20 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 6, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

Non-Invasive Neurostimulation For the Relief of Symptoms Associated With Migraine

NCT01532830
View directory record Official record
Conditions
Migraine
Interventions
n-VNS
Device
Lead sponsor
ElectroCore INC
Industry
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
3
States / cities
San Francisco, California • New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2018 · Synced Sep 6, 2026, 9:58 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effect of (TaVNS) on Anxiety and Brain Function in Distressed Health Care Workers

NCT05132881
View directory record Official record
Conditions
Anxiety, Distress, Emotional, Effects of Vibration, Healthy
Interventions
Neuvana 2.0 Transcutaneous Auricular Vagal Nerve Stimulation (TaVNS), Waitlist Control, Healthy Controls: Substudy Group III, Distressed Workers: Subgroup II
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
21 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 6, 2026, 9:58 PM EDT
Recruiting Not applicable Interventional

The Effect of Transcutaneous Vagal Nerve Stimulation (tVNS) on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage

NCT07131696
View directory record Official record
Conditions
Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Cerebral, Transcutaneous Vagal Nerve Stimulation (tVNS), Endovascular Treatment
Interventions
Transcutaneous Vagal Nerve Stimulation
Device
Lead sponsor
Marshall Holland
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 6, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

Neuromodulation Using Vagus Nerve Stimulation Following Ischemic Stroke as Therapeutic Adjunct

NCT05390580
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
transcutaneous auricular vagal nerve stimulation, Sham transcutaneous vagal nerve stimulation
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Sep 6, 2026, 9:58 PM EDT
Active, not recruiting No phase listed Observational

Vagus Nerve Response in Gastroparesis Patients

NCT04207996
View directory record Official record
Conditions
Gastroparesis
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 6, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

Addressing Disparities in Neuromodulation for Rehabilitation: A Mixed Methods Approach to Optimize Access for Underrepresented Racial Minorities

NCT05896202
View directory record Official record
Conditions
Neuropathic Pain
Interventions
taVNS Video, Educational materials, TMS Video
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 6, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

Vagal Nerve Stimulation and Glucose Metabolism

NCT01117311
View directory record Official record
Conditions
Type 2 Diabetes, Obesity, Gastric Emptying
Interventions
VNB on, VNB off
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
35 Years to 75 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 5, 2014 · Synced Sep 6, 2026, 9:58 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations

NCT07424365
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Parkinsons Disease (PD), Healthy Adult
Interventions
transcutaneous auricular vagus nerve stimulation, sham stimulation
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 6, 2026, 9:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Home Operations Utilizing Stimulation

NCT04484285
View directory record Official record
Conditions
Cognitive Performance
Interventions
Transcutaneous Vagal Nerve Stimulation (tVNS)
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 19, 2025 · Synced Sep 6, 2026, 9:58 PM EDT
Completed Not applicable Interventional

tAN for PTSD and OUD in Buprenorphine Therapy

NCT06130501
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Opioid Use Disorder
Interventions
Sparrow Ascent tAN, Sparrow Ascent Active Sham
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cape Girardeau, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 6, 2026, 9:58 PM EDT
Enrolling by invitation Not applicable Interventional

Pupillary Dilation During Post-Auricular Vagal Nerve Stimulation

NCT05870527
View directory record Official record
Conditions
Hearing Loss
Interventions
Electrical stimulator
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 6, 2026, 9:58 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Vagus Nerve Stimulation in Rheumatoid Arthritis

NCT00859859
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Vagus Nerve Stimulation
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Jul 19, 2011 · Synced Sep 6, 2026, 9:58 PM EDT
Recruiting Phase 3 Interventional

Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3

NCT05834478
View directory record Official record
Conditions
Withdrawal Symptoms, Opioid Use Disorder, Opioid Use
Interventions
Transcutaneous Cervical Vagal Nerve Stimulation, Sham Stimulation, [F-18]Fallypride
Device · Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 75 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
6
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 6, 2026, 9:58 PM EDT
Withdrawn Not applicable Interventional

Using Transcutaneous Auricular Vagus Nerve Stimulation to Treat Acute Alcohol Withdrawal

NCT04159909
View directory record Official record
Conditions
Alcohol Withdrawal, Alcohol Use Disorder
Interventions
Transcutaneous Nerve Stimulation, Sham Stimulation
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Sep 6, 2026, 9:58 PM EDT
Recruiting Not applicable Interventional

Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)

NCT07523685
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder PTSD, PTSD - Post Traumatic Stress Disorder, Post Traumatic Stress Disorder, Post Traumatic Stress Disorders, Post-traumatic Stress Disorder (PTSD), Post-Traumatic Stress Disorder, PTSD
Interventions
non-invasive vagus nerve stimulation
Device
Lead sponsor
Acacia Clinics
Industry
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sunnyvale, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Sep 6, 2026, 9:58 PM EDT