- Conditions
- Nicotine Dependence, Cigarettes
- Interventions
- AI-enhanced smartphone app, AI-enhanced smartphone app, but with delayed access
- Behavioral
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- 14 Years to 20 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Buffalo, New York
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Showing 1–24
of 29
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Cigarette Smoking
- Interventions
- E-cigarette (EC), Nicotine Replacement Therapy (NRT), Harm-Reduction Counseling, Ecological Momentary Intervention (EMI) Text Messaging
- Other · Behavioral
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Nicotine Dependence, E-Cig Use
- Interventions
- Nicotine patch, Phone Counseling, Digital Coaching
- Drug · Behavioral
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years to 24 Years
- Enrollment
- 508 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Behavior, Health Risk, Implementation Science, E Cigarette Use, Cessation, Smoking, Incentives, Engagement, Patient, Peer Support, Media Literacy
- Interventions
- Text-massaging suport, Financial incentive, Media literacy
- Behavioral
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 19 Years to 29 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- Vaping Behaviors, Message Exposure, Young Adults
- Interventions
- Intervention, Control
- Other
- Lead sponsor
- University of Hawaii
- Other
- Eligibility
- 18 Years to 24 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Honolulu, Hawaii
- Conditions
- Vaping, Cessation, Tobacco
- Interventions
- This is Quitting, Assessment only control, Waitlist control
- Behavioral · Other
- Lead sponsor
- Truth Initiative
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 1,681 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Smoking Cessation
- Interventions
- E-cigarette free access, E-cigarette/NRT/Zyban/Chantix Choice, Outcome Incentive arm, Loss framing incentive arm, Control
- Behavioral
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 6,006 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Smoking
- Interventions
- Enhanced Care, TAU
- Behavioral
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 204 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Tobacco Cessation
- Interventions
- This is Quitting, Assessment only Control
- Other
- Lead sponsor
- Truth Initiative
- Other
- Eligibility
- 18 Years to 24 Years
- Enrollment
- 2,588 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Vaping, Preventive Psychiatry, Social Networking
- Interventions
- Above the Influence-Vaping (ATI-V)
- Behavioral
- Lead sponsor
- University of Rochester
- Other
- Eligibility
- 12 Years to 18 Years
- Enrollment
- 3,950 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- Rochester, New York
- Conditions
- Vaping, Vaping Teens, Nicotine Dependence
- Interventions
- QuitVaping, This is Quitting (TIQ)
- Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 14 Years to 19 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Vaping, Vaping Cessation
- Interventions
- Behavioral: Quitting Program (TIQ)
- Device
- Lead sponsor
- St. Jude Children's Research Hospital
- Other
- Eligibility
- 13 Years to 24 Years
- Enrollment
- 539 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Vaping, Adolescent Behavior, Communication Research
- Interventions
- Tailored
- Other
- Lead sponsor
- Abramson Cancer Center at Penn Medicine
- Other
- Eligibility
- 13 Years to 20 Years
- Enrollment
- 1,155 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Nicotine Dependence, Tobacco-Related Carcinoma
- Interventions
- Smartphone app, Text Message, Survey Administration
- Behavioral · Other
- Lead sponsor
- Fred Hutchinson Cancer Center
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 1,178 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Tobacco Use
- Interventions
- Anti-vaping and anti-smoking digital advertising
- Behavioral
- Lead sponsor
- George Washington University
- Other
- Eligibility
- 18 Years to 24 Years
- Enrollment
- 2,800 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Tobacco-Related Carcinoma
- Interventions
- Behavioral Intervention, Survey Administration
- Behavioral · Other
- Lead sponsor
- Ohio State University Comprehensive Cancer Center
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 607 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- E-cigarette Use, Vaping
- Interventions
- Peer Messaging, Peer Coaching via Text, Gamification, E-Cigarette Cessation Materials
- Behavioral · Other
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 13 Years to 19 Years
- Enrollment
- 71 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts
- Conditions
- Nicotine Vaping
- Interventions
- YES-CAN! program
- Behavioral
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 9 Years and older
- Enrollment
- 1,166 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Vaping, E-cigarette Use, Electronic Cigarette Use
- Interventions
- Vape Messaging Intervention
- Behavioral
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 18 Years to 24 Years
- Enrollment
- 569 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Burlington, Vermont
- Conditions
- Tobacco-Related Carcinoma
- Interventions
- Health Education, Interview, Smoking Cessation Intervention, Survey Administration, Text Message-Based Navigation Intervention
- Behavioral · Other
- Lead sponsor
- Ohio State University Comprehensive Cancer Center
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 292 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- E-cigarette Use
- Interventions
- E-cigarette cessation text-messaging intervention, Standard care control using standard national resources
- Behavioral
- Lead sponsor
- Jovan Gwon, PhD, RN, FIAAN
- Other
- Eligibility
- 18 Years to 24 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Tobacco Dependence
- Interventions
- CEASE, CEASE + BIO
- Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 865 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Nicotine Vaping, Nicotine Use Disorder
- Interventions
- quitSTART Mobile Application, Chatbot Feature in quitSTART Mobile Application
- Device · Behavioral
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 15 Years to 25 Years
- Enrollment
- 189 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Vaping, Social Support
- Interventions
- Quit the Hit (QTH) Program with Peer Mentoring
- Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 13 Years to 29 Years
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- San Francisco, California