- Conditions
- Hypercapnic Respiratory Failure, Chronic Obstructive Pulmonary Disease, Dyspnea, Hypercapnic Acidosis
- Interventions
- High Velocity Nasal Insufflation (HVNI), Noninvasive Positive Pressure Ventilation (NIPPV)
- Device
- Lead sponsor
- Vapotherm, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 68 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 7
- States / cities
- Los Angeles, California • Oxnard, California • Washington D.C., District of Columbia + 4 more
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- Conditions
- Acute Respiratory Failure
- Interventions
- Noninvasive positive pressure ventilation (NIPPV), Vapotherm
- Device
- Lead sponsor
- Vapotherm, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 204 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 5
- States / cities
- Athens, Georgia • Florence, South Carolina • Chattanooga, Tennessee + 2 more
- Conditions
- Mild-Moderate Obstructive Sleep Disordered Breathing
- Interventions
- High-Flow Therapy, Continuous Positive Airway Pressure
- Device
- Lead sponsor
- Vapotherm, Inc.
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Glen Burnie, Maryland
- Conditions
- Pulmonary Disease, Chronic Obstructive, Respiratory Insufficiency
- Interventions
- Vapotherm High Flow Therapy, Non-invasive positive pressure ventilation
- Device
- Lead sponsor
- Vapotherm, Inc.
- Industry
- Eligibility
- 50 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2014
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Infant, Premature, Neonatal Respiratory Distress, Oxygen Saturation, Bronchopulmonary Dysplasia
- Interventions
- Automated Control, Manual Control
- Device
- Lead sponsor
- Vapotherm, Inc.
- Industry
- Eligibility
- Not listed
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 3
- States / cities
- Washington D.C., District of Columbia • Salt Lake City, Utah • Seattle, Washington
- Conditions
- Healthy Adult Volunteers
- Interventions
- HFNC, CPAP
- Device
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland