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Showing 481–504 of 1,481 matching trials from the live ClinicalTrials.gov search.
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Doravirine, Rifapentine and Isoniazid Interaction

NCT03886701
Conditions
Latent Tuberculosis, Human Immunodeficiency Virus, Rifamycins Causing Adverse Effects in Therapeutic Use, Drug Interaction Potentiation
Interventions
Doravirine (DOR), Rifapentine (RPT), Isoniazid (INH)
Drug
Lead sponsor
Walter K. Kraft
Other
Eligibility
18 Years to 60 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Metastatic Castration Sensitive Prostate Cancer
Interventions
Luteinizing Hormone-Releasing Hormone (LHRH) analog, Androgen Receptor Signal Inhibitor (ARSI), Docetaxel
Drug
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Tampa, Florida
Completed Not applicable Interventional

Aversive Therapy for Smoking Cessation

NCT03450148
Conditions
Smoking Cessation
Interventions
Pavlok wristband with electric stimulus, Pavlok wristband without electric stimulus
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 99 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Obesity, Diabetes
Interventions
Weight loss intervention
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 75 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Conditions
Breast Cancer, Cancer
Interventions
Venetoclax, Capecitabine
Drug
Lead sponsor
AbbVie
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
11
States / cities
Joliet, Illinois • Boston, Massachusetts • Minneapolis, Minnesota + 7 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cervical Electrical Stimulation for ALS

NCT03411863
Conditions
Amyotrophic Lateral Sclerosis
Interventions
CES at rest, CES plus active hand or wrist movements
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
The Bronx, New York
Completed Not applicable Interventional

Glaucoma Evaluation With the P200TE

NCT06305481
Conditions
Glaucoma
Interventions
P200TE
Device
Lead sponsor
Optos, PLC
Industry
Eligibility
22 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
2
States / cities
Cajon, California • Bellevue, Washington
Conditions
Obesity
Interventions
Discovery Vitality base program, Communication, Charitable Incentive, Prize Draw Incentive, Direct Payment, Free Choice
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Conditions
HIV
Interventions
PATH For Triples, Treatment as Usual
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Substance-Related Disorders, Depressive Disorder, Behavioral Symptoms, Risk-Taking, Sexual Behavior
Interventions
LETS ACT, LETS ACT-SE, Treatment as Usual
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 55 Years
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Raleigh, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

The Alzheimer's Companion Engagement (ACE) Project.

NCT04856462
Conditions
Stress, Psychological, Adaptation, Psychological
Interventions
Education Support
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Obesity
Interventions
Advice on diet, physical activity, and behavior change, Instruction in food portion size, Provision of pre-portioned foods, Advice on healthy eating for weight loss
Behavioral · Other
Lead sponsor
Penn State University
Other
Eligibility
20 Years to 65 Years · Female only
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
University Park, Pennsylvania
Conditions
Subluxation
Interventions
Chiropractic adjustment, Sham adjustment
Procedure
Lead sponsor
Life University
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Marietta, Georgia
Conditions
Vaccines
Interventions
HPV Vaccine Reminder Recall - Autodialer, HPV Vaccine Reminder Recall - Texting
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
11 Years to 14 Years
Enrollment
37,003 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Venus Leg Ulcers
Interventions
EscharEx (EX-03), Placebo (Gel vehicle), Non-surgical standard of care (NSSOC)
Drug · Other
Lead sponsor
MediWound Ltd
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Maimi, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Sensory Perception of Sweet Flavors in E-Cigarette

NCT03332953
Conditions
Smoking
Interventions
E-cigarettes with varying concentrations of nicotine & flavor
Other
Lead sponsor
Oregon State University
Other
Eligibility
18 Years to 35 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Corvallis, Oregon
Conditions
Ovarian Cancer
Interventions
Pre-study Questionnaire, Educational Presentations, CAM Therapies, Post-study Questionnaire
Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Advanced Solid Tumor, High Grade Serous Adenocarcinoma of Ovary, Squamous Non-small-cell Lung Cancer, Triple Negative Breast Cancer, Head and Neck Squamous Cell Carcinoma, Ovarian Carcinosarcoma, Uterine Carcinosarcoma, Uterine Serous Carcinoma, Endometrium Cancer, Chromosomal Instability
Interventions
VLS-1488
Drug
Lead sponsor
Volastra Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
14
States / cities
Los Angeles, California • Newport Beach, California • Aurora, Colorado + 11 more
Conditions
Diabetes Mellitus, Type 2, Diabetes Mellitus
Interventions
OT Diabetes Self-Management Intervention
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Mesa, Arizona
Conditions
Autism, Development Delay, Typical Development
Interventions
Virtual Reality, Standard of Care
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
8 Years to 19 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Sacramento, California
Conditions
Nasal Valve Collapse, Nose Enhancement
Interventions
Low-temperature radio-frequency reshaping of autologous cartilage nasal and/or auricular cartilage
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Indianapolis, Indiana
Active, not recruiting Not applicable Interventional

Re-entry Continuum for Brain Injury

NCT04386681
Conditions
Traumatic Brain Injury, Recidivism
Interventions
Reentry Continuum for Brain Injury (RCBI)
Behavioral
Lead sponsor
Rehabilitation Hospital of Indiana
Other
Eligibility
18 Years and older · Male only
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Greencastle, Indiana
Conditions
Post-Acute COVID-19 Syndrome, Fatigue
Interventions
Dietary intervention to mitigate Post-Acute COVID-19 Syndrome, Attention Control
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
50 Years to 94 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Advanced Solid Tumors Cancer
Interventions
ABBV-368, ABBV-181
Drug
Lead sponsor
AbbVie
Industry
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
10
States / cities
La Jolla, California • Sacramento, California • Stanford, California + 7 more