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ClinicalTrials.gov public records Last synced Oct 23, 2026, 2:06 AM EDT

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Showing 97–120 of 130 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Vascular Function Testing Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms of Altered Ventilatory Control in Heart Failure

NCT02421341
View directory record Official record
Conditions
Heart Failure
Interventions
Fentanyl, Catheters, Exercise, DEXA, Pulmonary Function Tests, Blood Draw, Chemosensitivity Test, Placebo
Drug · Procedure · Other + 1 more
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 16, 2021 · Synced Oct 23, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Prediction of Cardiovascular Events in Vulnerable Patients Following Acute Coronary Syndrome

NCT01500902
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
EndoPAT testing (non invasive device), WatchPAT testing (non-invasive device)
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Oct 23, 2026, 2:06 AM EDT
Not listed Not applicable Interventional

Weathering the Storm: Lung, Heart, and Brain Vascular Rehabilitation for COVID-19

NCT04887272
View directory record Official record
Conditions
Covid19
Interventions
Supervised Exercise Training Protocol, Inspiratory Muscle and Exercise Training
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 14, 2021 · Synced Oct 23, 2026, 2:06 AM EDT
Recruiting No phase listed Observational

WISE CVD - Continuation (WISE HFpEF)

NCT02582021
View directory record Official record
Conditions
Microvascular Coronary Dysfunction, Cardiovascular Disease
Interventions
Coronary Angiography, Coronary Reactivity Testing, Cardiac Magnetic Resonance Imaging, Cardiac Magnetic Resonance Angiography, Computed Coronary Tomographic Angiography, Rest-Stress Millar Testing, Aortic vasorelaxation tests
Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2030
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 23, 2026, 2:06 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Development of a Clinically-relevant Test for Assessment of Cerebral Vascular Function

NCT04336852
View directory record Official record
Conditions
Cerebrovascular Disorders, Cerebrovascular Disease
Interventions
Flow mediated dilation (brachial and femoral arteries), Cerebral vascular reactivity to carbon dioxide (CO2), Cerebral vascular function test
Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
2
States / cities
Chicago, Illinois • Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Oct 23, 2026, 2:06 AM EDT
Completed Phase 4 Interventional Results available

The Effect of Vericiguat on Peripheral Vascular Function, Patient Health Status and Inflammation

NCT05420012
View directory record Official record
Conditions
Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF)
Interventions
Vericiguat, Placebo
Drug
Lead sponsor
Josef Stehlik
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 23, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Hot Flashes and Neurovascular Function in Women

NCT05193968
View directory record Official record
Conditions
Hot Flashes, Menopause, Vasomotor System; Labile
Interventions
Sympathoexcitatory stressors, Sodium Nitroprusside, Acetylcholine, Terbutaline, Norepinephrine
Other · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 60 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 23, 2026, 2:06 AM EDT
Withdrawn Not applicable Interventional

Olive Oil and Cardiovascular Health

NCT01983943
View directory record Official record
Conditions
Cardiovascular Disease, Endothelial Function
Interventions
Hydroxytyrosol, the active ingredient in olive oil., Placebo, Nutrition counseling, Endopat
Dietary Supplement · Behavioral · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Oct 23, 2026, 2:06 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Mechanisms of Cerebrovascular Control

NCT02936687
View directory record Official record
Conditions
Metabolic Syndrome X
Interventions
NOS Inhibition, ET-1 Inhibition, NOS Inhibition Placebo, 3 Tesla MRI, Intravenous Catheter, Oral Glucose Tolerance Test, ET-1 Inhibition Placebo
Drug · Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 45 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 18, 2021 · Synced Oct 23, 2026, 2:06 AM EDT
Withdrawn No phase listed Observational

Platelet Function Testing Help and Intraoperative Bleeding Risk for Patients Who Are on Plavix Prior to Surgery

NCT00653900
View directory record Official record
Conditions
Perioperative Bleeding
Interventions
Not listed
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 8, 2019 · Synced Oct 23, 2026, 2:06 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Heat Therapy, Functional Capacity, and Vascular Health in Older Adults

NCT05706181
View directory record Official record
Conditions
Aging Well, Walking, Difficulty, Hyperemia
Interventions
Home-based leg heat therapy, Home-based sham therapy
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
55 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 23, 2026, 2:06 AM EDT
Completed Phase 4 Interventional Results available

ISCHEMIA-Chronic Kidney Disease Trial

NCT01985360
View directory record Official record
Conditions
Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Myocardial Ischemia, Kidney Disease, End Stage Renal Failure on Dialysis
Interventions
Cardiac Catheterization, Coronary Artery Bypass Graft Surgery, Percutaneous Coronary Intervention, Lifestyle, Medication
Procedure · Behavioral · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years and older
Enrollment
777 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 18, 2021 · Synced Oct 23, 2026, 2:06 AM EDT
Recruiting No phase listed Observational

Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias

NCT06306963
View directory record Official record
Conditions
Gastric Antral Vascular Ectasia, Cirrhosis, Chronic Kidney Disease
Interventions
Gastric Emptying Breath Test
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
19 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 23, 2026, 2:06 AM EDT
Withdrawn Phase 4 Interventional

Ertugliflozin Versus Hydrochlorothiazide in Reducing Sympathetic Neural Overactivity in Patients With Hypertension and Recently-diagnosed Type 2 Diabetes.

NCT03640221
View directory record Official record
Conditions
Hypertension, Diabetes Mellitus, Type 2
Interventions
Ertugliflozin, Hydrochlorothiazide 12.5mg, Microneurography, SKNA recordings, Static Handgrip, Post-handgrip forearm vascular occlusion, Testing of the Arterial Baroreflex Function
Drug · Device · Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
35 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2020 · Synced Oct 23, 2026, 2:06 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

PNS to Improve Vascular Function and Limb Health in Veterans

NCT07696988
View directory record Official record
Conditions
Lower Limb Amputees, Diabetes
Interventions
Chronically Implanted Neural and Muscular Interface, Peripheral Nerve Stimulation (PNS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 23, 2026, 2:06 AM EDT
Completed Phase 2 Interventional Results available

Dietary Nitrate and Exercise to Augment Exercise Training Benefits in Subjects With DM+PAD

NCT01785524
View directory record Official record
Conditions
Peripheral Arterial Disease, Type II Diabetes Mellitus
Interventions
Beetroot Juice (Beet-It Stamina Shot) and Exercise Training, Placebo Comparator Beverage (Beet-It Stamina Shot) & Exercise Training
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
50 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2017 · Synced Oct 23, 2026, 2:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cardioprotective Activities Of Whole Eggs On Vascular Endothelial Function In Prediabetic Adults

NCT02364570
View directory record Official record
Conditions
Prediabetes, Cardiovascular Disease
Interventions
Glucose (100g), Glucose (75g), Whole Eggs, Egg Whites, Egg Yolks
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 3, 2019 · Synced Oct 23, 2026, 2:06 AM EDT
Terminated Phase 2 Interventional

CXA-10 Study in Subjects With Pulmonary Arterial Hypertension

NCT04053543
View directory record Official record
Conditions
PAH
Interventions
CXA-10
Drug
Lead sponsor
Complexa, Inc.
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
31
States / cities
Birmingham, Alabama • Tucson, Arizona • Anaheim, California + 27 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2020 · Synced Oct 23, 2026, 2:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluate Long Term Cardiovascular and Pulmonary Complications After COVID-19 With Point of Care Ultrasound

NCT04756193
View directory record Official record
Conditions
Covid19, Echocardiography, Ultrasound
Interventions
Point of care ultrasound including echocardiography, lung ultrasound, vascular ultrasound
Diagnostic Test
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 30, 2024 · Synced Oct 23, 2026, 2:06 AM EDT
Completed Not applicable Interventional Results available

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

NCT01471522
View directory record Official record
Conditions
Cardiovascular Diseases, Coronary Disease, Coronary Artery Disease, Heart Diseases, Myocardial Ischemia
Interventions
cardiac catheterization, coronary artery bypass graft surgery, percutaneous coronary intervention, Lifestyle, Medication
Procedure · Behavioral · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years and older
Enrollment
5,179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
109
States / cities
Birmingham, Alabama • Yuma, Arizona • Beverly Hills, California + 82 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2023 · Synced Oct 23, 2026, 2:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction During Disuse

NCT04351113
View directory record Official record
Conditions
Aging, Oxidative Stress, Vascular Endothelium, Skeletal Muscle, Antioxidants
Interventions
MITO-AO, PB-125, Placebo, Passive Leg Movement (PLM), Plantar flexion, Isometric knee extensor test, Bed rest
Dietary Supplement · Other
Lead sponsor
Joel Trinity
Other
Eligibility
65 Years to 85 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 23, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional

Vascular Mechanisms, Functional Outcomes, & Exercise Among Persons With Multiple Sclerosis With Hypertension

NCT06554340
View directory record Official record
Conditions
Multiple Sclerosis, Hypertension
Interventions
Home-based aerobic training
Behavioral
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 23, 2026, 2:06 AM EDT
Recruiting No phase listed Observational

Post-Stroke Sensory Reweighting on Walking and Balance Outcomes

NCT06727097
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Posturography, Walking Speed, Instrumented 7M Timed UP and GO, Fall Event Records, MRI (3T)
Diagnostic Test · Other
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 23, 2026, 2:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Spice Consumption on Postprandial Vascular Function

NCT03063320
View directory record Official record
Conditions
Cardiovascular Risk Factor
Interventions
Spice blend
Other
Lead sponsor
Penn State University
Other
Eligibility
30 Years to 75 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 18, 2023 · Synced Oct 23, 2026, 2:06 AM EDT