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Showing 1–24 of 97 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Vaseline Clear all
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Emollient Therapy on the Skin Barrier

NCT01291940
View directory record Official record
Conditions
Atopic Dermatitis, Eczema
Interventions
Pediatric Moisturizer, Adult Moisturizer
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
3 Months to 99 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 14, 2019 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Early Phase 1 Interventional

Actinic Keratosis Study

NCT02019355
View directory record Official record
Conditions
Actinic Keratosis
Interventions
5-fluorouracil 5% cream, Calcipotriol 0.005% ointment, Vaseline
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
50 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 18, 2016 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment

NCT05618912
View directory record Official record
Conditions
Scar, Skin Scarring, Skin Cancer, Wound Heal, Wound of Skin, Surgical Wound, Patient Satisfaction, Patient Preference, Surgical Incision
Interventions
Hydrocolloid dressing, Petrolatum jelly dressing
Device · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Carmel, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Not applicable Interventional Results available

The Role of Skin Care Regimen in Skin Health

NCT03497130
View directory record Official record
Conditions
Itching, Xerosis
Interventions
skin care regimen
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Dermal Irritation, Sensitization and Cumulative Irritation Potential of 6% Bemotrizinol

NCT05260359
View directory record Official record
Conditions
Sunburn
Interventions
6% Bemotrizinol (BEMT) in a basic sunscreen oil formulation, 6% Bemotrizinol (BEMT) dispersion in petrolatum, Sunscreen oil vehicle with 10% ethanol as penetration enhancer without BEMT, Petrolatum vehicle, 0.9% Saline, Sodium Lauryl Sulfate 0.1% (SLS), Undosed patch
Drug · Other
Lead sponsor
dsm-firmenich Switzerland AG
Industry
Eligibility
18 Years to 75 Years
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Not applicable Interventional Results available

Treatment of Chronic and Non-Chronic Wounds in Patients With Recessive Dystrophic Epidermolysis Bullosa Using Helicoll Collagen Dressings Versus Standard of Care

NCT01716169
View directory record Official record
Conditions
Epidermolysis Bullosa Dystrophica, Epidermolysis Bullosa
Interventions
Helicoll, Standard of Care Dressings
Device
Lead sponsor
Stanford University
Other
Eligibility
7 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 4, 2016 · Synced Sep 2, 2026, 1:55 PM EDT
Withdrawn Phase 2 Interventional

Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipients

NCT04329221
View directory record Official record
Conditions
Cutaneous Squamous Cell Carcinoma, Actinic Keratoses, Skin Cancer, Organ Transplant Recipients, Immunotherapy
Interventions
Calcipotriol Only Product in Cutaneous Dose Form, Vaseline, Topical 5FU
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Boston, Massachusetts • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Not applicable Interventional

Impact of Early Post-Operative Water Exposure on Complications of Cutaneous Surgeries

NCT01773694
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Early Water Exposure
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
507 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 31, 2021 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Phase 3 Interventional Results available

Retapamulin as a Decolonizing Agent for MRSA

NCT03304873
View directory record Official record
Conditions
MRSA
Interventions
Retapamulin, Placebo Ointment
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
9 Months to 17 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Sep 2, 2026, 1:55 PM EDT
Recruiting Not applicable Interventional

Post-market Cosmetic Evaluation of Ariessence™ Pure PDGF+ Following Ablative Laser

NCT07718347
View directory record Official record
Conditions
Immediate Post-Treatment Care, Aging Mid-Face, Aging
Interventions
ariessence pure PDGF+™ is a sterile aqueous formulation containing Hyaluronic Acid and pure platelet-derived growth factor (PDGF).
Other
Lead sponsor
Lynch Regenerative Medicine
Network
Eligibility
40 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Sacramento, California • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of Nitrogen Mustard in Treatment of Mycosis Fungoides

NCT00168064
View directory record Official record
Conditions
Mycosis Fungoides
Interventions
mechlorethamine-MCH (nitrogen mustard)
Drug
Lead sponsor
Yaupon Therapeutics
Industry
Eligibility
Not listed
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
12
States / cities
Stanford, California • Chicago, Illinois • New York, New York + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2012 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Not applicable Interventional Results available

Treatment of Staphylococcus Aureus Colonization in Hand Eczema

NCT01591785
View directory record Official record
Conditions
Hand Eczema, Foot Eczema
Interventions
Retapamulin 1% ointment, Placebo
Drug
Lead sponsor
Gary Goldenberg
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Not applicable Interventional Results available

Compatibility of a Mild, Moisturizing Hand Cleanser for Patients With Mild to Moderate Hand Dermatitis

NCT00843466
View directory record Official record
Conditions
Hand Dermatosis
Interventions
Mild, moisturizing hand cleanser
Other
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2018 · Synced Sep 2, 2026, 1:55 PM EDT
Withdrawn Phase 3 Interventional

Diclofenac Gel in the Treatment of Cervicogenic Headache

NCT05312645
View directory record Official record
Conditions
Cervicogenic Headache
Interventions
Diclofenac 1% Topical, Petroleum Jelly
Drug · Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Phase 4 Interventional Results available

The Impact of Treating Staphylococcus Aureus Infection and Colonization on the Clinical Severity of Atopic Dermatitis

NCT00179959
View directory record Official record
Conditions
Atopic Dermatitis
Interventions
Sodium hypochlorite (bleach) baths, Mupirocin ointment, Water, Petrolatum Ointment
Drug
Lead sponsor
Northwestern University
Other
Eligibility
6 Months to 17 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 7, 2014 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Not applicable Interventional Results available

Pre-Shave Gel and Brush in Pseudofolliculitis Barbae

NCT03043534
View directory record Official record
Conditions
Pseudofolliculitis Barbae
Interventions
shave gel, Brush
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
20 Years to 60 Years · Male only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Document the Effect of Petrolatum on Innate Immune Responses in the Skin

NCT02338076
View directory record Official record
Conditions
Skin Disease
Interventions
Petrolatum application under occlusion
Drug
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 15, 2017 · Synced Sep 2, 2026, 1:55 PM EDT
Terminated Phase 4 Interventional Results available

Comparison of Collagenase With Antibiotic Ointment of Minor Partial Thickness Burns

NCT02673229
View directory record Official record
Conditions
Burn, Partial Thickness
Interventions
Collagenase Santyl, Bacitracin
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
2 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Sep 2, 2026, 1:55 PM EDT
Terminated Phase 1 Interventional

Topical Calcipotriene Treatment for Breast Cancer Immunoprevention

NCT03596073
View directory record Official record
Conditions
Breast Cancer
Interventions
Topical Calcipotriene Ointment, Topical Vaseline
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Not applicable Interventional Results available

Wet-to-dry vs Petrolatum & Non-stick Dressings After Hidradenitis Suppurativa Surgery

NCT05194969
View directory record Official record
Conditions
Hidradenitis Suppurativa, Surgical Wound
Interventions
Wet-to-Dry Dressings, Petrolatum with Non-Stick Gauze
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 99 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Sep 2, 2026, 1:55 PM EDT
Recruiting Phase 1 Interventional

Topical 0.5% Timolol Solution for Healing Lower Extremity Wounds

NCT06941467
View directory record Official record
Conditions
Wound Healing, Mohs Micrographic Surgery
Interventions
Timolol Maleate Solution, Standard of Care
Drug · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2025 · Synced Sep 2, 2026, 1:55 PM EDT
Active, not recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation

NCT05535738
View directory record Official record
Conditions
Skin Inflammation, Allergic Contact Dermatitis
Interventions
Squaric Acid Dibutyl Ester, Known patch test allergens, Dupilumab, Adalimumab, Ustekinumab, Guselkumab, Canakinumab, Sarilumab, Triamcinolone Acetonide, Betamethasone Valerate, Fluticasone Propionate, Microneedle, Suction blistering, Skin punch biopsy
Drug · Other · Device + 1 more
Lead sponsor
Wei-Che Ko
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Not applicable Interventional Results available

Study of KeraStat Cream for Radiation Dermatitis During Head and Neck Radiotherapy

NCT04173247
View directory record Official record
Conditions
Head and Neck Cancer, Radiation Dermatitis
Interventions
KeraStat Cream, Routine Skin Care - Commercially Available Agents
Device · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Sep 2, 2026, 1:55 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Topical Antibiotic Prophylaxis for Eyelids

NCT03199911
View directory record Official record
Conditions
Antibiotic Side Effect, Eyelid; Wound, Eyelid Diseases, Surgical Wound Infection, Surgical Wound, Recent, Surgical Incision, Skin Cancer Face, Antibiotic Allergy, Surgical Site Infection
Interventions
Topical Antibiotic Product, Topical Non-Antibiotic Ointment
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
401 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 20, 2020 · Synced Sep 2, 2026, 1:55 PM EDT