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ClinicalTrials.gov public records Last synced Sep 8, 2026, 1:22 AM EDT

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Showing 1–24 of 50 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Venous Closure Clear all
Active, not recruiting Phase 3 Interventional

Trial of Modifications to Radical Prostatectomy

NCT01407263
View directory record Official record
Conditions
Prostate Cancer
Interventions
Lymph node template, Transverse versus vertical closure, antibiotic prophylaxis, Hemostatic Agent
Procedure · Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years and older · Male only
Enrollment
3,204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2027
U.S. locations
5
States / cities
Basking Ridge, New Jersey • Montvale, New Jersey • Harrison, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 8, 2026, 1:22 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The CONFORMAL Early Feasibility Study

NCT03616028
View directory record Official record
Conditions
Non-valvular Atrial Fibrillation
Interventions
left atrial appendage closure
Device
Lead sponsor
Conformal Medical, Inc
Industry
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
11
States / cities
Jonesboro, Arkansas • Santa Monica, California • Manchester, New Hampshire + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 8, 2026, 1:22 AM EDT
Completed Not applicable Interventional Results available

Venclose RF Ablation System for the Treatment of IPVs

NCT04386785
View directory record Official record
Conditions
Chronic Venous Insufficiency
Interventions
Radiofrequency (RF) Thermal Ablation of Incompetent Perforator Veins
Device
Lead sponsor
Venclose, Inc.
Industry
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Tyler, Texas
Source: ClinicalTrials.gov public record
Updated May 26, 2022 · Synced Sep 8, 2026, 1:22 AM EDT
Completed Not applicable Interventional Results available

VenaSeal Sapheon Closure System Pivotal Study (VeClose)

NCT01807585
View directory record Official record
Conditions
Great Saphenous Vein (GSV) With Venous Reflux Disease
Interventions
VenaSeal SCS, ClosureFast Radiofrequency Ablation (RFA), Roll-in (VenaSeal SCS)
Device
Lead sponsor
Medtronic Endovascular
Industry
Eligibility
21 Years to 70 Years
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
10
States / cities
Scottsdale, Arizona • San Diego, California • Greenwood Village, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2018 · Synced Sep 8, 2026, 1:22 AM EDT
Not listed No phase listed Observational

AMBULATE Same Day Discharge Registry

NCT04203329
View directory record Official record
Conditions
Vascular Closure
Interventions
Femoral Venous Vascular Closure
Device
Lead sponsor
Cardiva Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
15
States / cities
Birmingham, Alabama • Scottsdale, Arizona • San Luis Obispo, California + 12 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2022 · Synced Sep 8, 2026, 1:22 AM EDT
Enrolling by invitation Not applicable Interventional

Percutaneous Closure Versus Figure-of-eight Suture for Hemostasis in Leadless Pacemaker Implantation.

NCT06837870
View directory record Official record
Conditions
Vascular Closure, Pacemaker Implantation, Leadless Pacemaker
Interventions
percutaneous suture mediated closure, Figure of Eight Suture
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 8, 2026, 1:22 AM EDT
Not listed Not applicable Interventional

Provant Therapy of Venous Stasis Ulcer Trial

NCT01050023
View directory record Official record
Conditions
Venous Stasis Ulcers
Interventions
Provant Device (Wound Therapy System), Provant Device - Inactive
Device
Lead sponsor
Southern California Institute for Research and Education
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
2
States / cities
Long Beach, California • Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2011 · Synced Sep 8, 2026, 1:22 AM EDT
Recruiting Not applicable Interventional

Tract Closure in PCNL

NCT07668817
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Floseal, Surgicel, Surgiflo, Balloon Tamponade
Device · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 8, 2026, 1:22 AM EDT
Recruiting Phase 4 Interventional

Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers

NCT07089602
View directory record Official record
Conditions
Diabetic Foot, DFU, Diabetic Foot Ulcer, Foot Ulcer, Diabetic, Ulcer Foot, Venous Leg Ulcer, Leg Ulcer, Leg Ulcers Venous, Ulcer
Interventions
Standard of Care DFU, Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU, Membrane Wrap-Lite™ DFU, Membrane Wrap-Hydro™ DFU, Standard of Care VLU, Tri-Membrane Wrap™ VLU, Membrane Wrap™ VLU, Membrane Wrap-Lite™ VLU, Membrane Wrap-Hydro™ VLU
Other
Lead sponsor
BioLab Holdings
Industry
Eligibility
18 Years and older
Enrollment
650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philidelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced Sep 8, 2026, 1:22 AM EDT
Terminated Not applicable Interventional Results available

Assessment of Wound Closure Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers (DFU) and With Living Cellular Skin Substitute in Treating Venous Leg Ulcers (VLU)

NCT04927702
View directory record Official record
Conditions
Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions
Synthetic Hybrid-Scale Fiber Matrix, Standard of Care, Living Cellular Skin Substitute
Device
Lead sponsor
Acera Surgical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
6
States / cities
Vista, California • Jacksonville, Florida • Miami Beach, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 8, 2026, 1:22 AM EDT
Recruiting Phase 4 Interventional

Evaluating Intact Fish Skin Graft and Standard of Care Versus Standard of Care Alone in Nonhealing Venous Leg Ulcers

NCT06693570
View directory record Official record
Conditions
Venous Leg Ulcer (VLU), Venous Leg Ulcers, Venous Leg, Nonhealing Venous Leg Ulcer
Interventions
Intact Fish Skin Graft (IFSG) + Standard of Care, Standard of Care
Other
Lead sponsor
Kerecis Ltd.
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Monroeville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Sep 8, 2026, 1:22 AM EDT
Terminated Phase 4 Interventional

Restore Calcium Alginate Dressing, Silver vs Aquacel Ag in the Treatment of Critically Colonized Venous Leg Ulcers

NCT01396304
View directory record Official record
Conditions
Venous Ulcer, Infection
Interventions
Restore Calcium Alginate Dressing, AquaCel Ag Wound Dressing
Device
Lead sponsor
Hollister Wound Care LLC
Industry
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
5
States / cities
St. Petersburg, Florida • Shreveport, Louisiana • Holmdel, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2013 · Synced Sep 8, 2026, 1:22 AM EDT
Terminated Phase 1 Interventional

Mechanical Thrombectomy Blood Flow Reversal

NCT06721338
View directory record Official record
Conditions
Stroke, Large Vessel Occlusion
Interventions
Mechanical thrombectomy via blood flow reversal using BOBBY balloon guide catheter
Device
Lead sponsor
MediSys Health Network
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Jamaica, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Sep 8, 2026, 1:22 AM EDT
Completed Not applicable Interventional Results available

AMBULATE Continued Access Protocol to Evaluate the Cardiva Mid-Bore Venous Vascular Closure System (VVCS)

NCT03573206
View directory record Official record
Conditions
Surgical Wound
Interventions
Cardiva Mid-Bore Venous Vascular Closure Device (VVCS)
Device
Lead sponsor
Cardiva Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
3
States / cities
Atlanta, Georgia • Ridgewood, New Jersey • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2023 · Synced Sep 8, 2026, 1:22 AM EDT
Completed Not applicable Interventional Results available

Perclose Multi-Access Duplex Ultrasound (DUS) Study

NCT04904809
View directory record Official record
Conditions
Arrhythmia
Interventions
Perclose ProGlide SMC System and/or Perclose ProStyle SMCR System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Atlanta, Georgia • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 19, 2023 · Synced Sep 8, 2026, 1:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Safety and Efficacy of an Extravascular, Water-Soluble Sealant for Venous Access-Site Closure

NCT02438475
View directory record Official record
Conditions
Cardiac Diagnostic Procedure, Cardiac Interventional Procedure, Femoral Access Site Closure
Interventions
Mynx Vascular Closure System, Manual Compression
Device · Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Clinton, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Sep 8, 2026, 1:22 AM EDT
Not listed Phase 3 Interventional

Evaluation of CureXcell® in Treating Chronic Venous Leg Ulcers

NCT02130310
View directory record Official record
Conditions
Chronic Venous Leg Ulcers
Interventions
CureXcell®, Placebo injection
Biological · Other
Lead sponsor
Macrocure Ltd.
Industry
Eligibility
18 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
28
States / cities
Mesa, Arizona • Phoenix, Arizona • Carlsbad, California + 25 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2015 · Synced Sep 8, 2026, 1:22 AM EDT
Active, not recruiting Not applicable Interventional

Venous Sinus Stenting With the River Stent in IIH

NCT03556085
View directory record Official record
Conditions
Idiopathic Intracranial Hypertension
Interventions
Venous sinus stenting (Serenity River)
Device
Lead sponsor
Serenity Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
6
States / cities
Jacksonville, Florida • Buffalo, New York • Manhasset, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 8, 2026, 1:22 AM EDT
Recruiting Phase 4 Interventional

A Multicenter, Prospective, Controlled Modified Multi-Platform Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers.

NCT07364630
View directory record Official record
Conditions
Diabetic Foot Ulcer, Foot Ulcer Chronic, DFU, Ulcer Foot, Venous Leg Ulcer (VLU), Venous Leg Ulcer, Venous Ulcer, Leg Ulcers, Ulcer
Interventions
Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU, Membrane Wrap-Lite™ DFU, Membrane Wrap-Hydro™ DFU, Tri-Membrane Wrap™ VLU, Membrane Wrap™ VLU, Membrane Wrap-Lite™ VLU, Membrane Wrap-Hydro™ VLU
Other
Lead sponsor
BioLab Holdings
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philidelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 8, 2026, 1:22 AM EDT
Completed No phase listed Observational

AMBULATE VASCADE MVP Same Day Discharge Retrospective Registry

NCT04538781
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
VASCADE MVP VVCS
Device
Lead sponsor
Cardiva Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
497 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
4
States / cities
San Luis Obispo, California • Washington D.C., District of Columbia • Burlington, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2021 · Synced Sep 8, 2026, 1:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of DT56a (Femarelle) on the Coagulation System in the Treatment of Postmenopausal Women

NCT00883272
View directory record Official record
Conditions
Menopause, Thrombophilia
Interventions
DT56a (Femarelle) [Se-cure pharmaceuticals, Dalton, Israel]
Dietary Supplement
Lead sponsor
NYU Langone Health
Other
Eligibility
40 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Sep 8, 2026, 1:22 AM EDT
Withdrawn Not applicable Interventional

Comparison Study for Safety and Efficacy of Two Devices for the Treatment of the Great Saphenous Vein

NCT01173419
View directory record Official record
Conditions
Varicose Veins, Venous Insufficiency
Interventions
VNUS RF ClosureFAST, VenaCure EVLT NeverTouch
Device
Lead sponsor
Angiodynamics, Inc.
Industry
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
6
States / cities
Sacramento, California • Bradenton, Florida • Melrose Park, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2012 · Synced Sep 8, 2026, 1:22 AM EDT
Recruiting Phase 4 Interventional

Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.

NCT06826339
View directory record Official record
Conditions
Venous Leg Ulcer, Venous Leg, Diabetic Foot, Diabetic Foot Ulcer, Foot Ulcer, Diabetic, Ulcer Foot, Leg Ulcer, Ulcer Venous, Ulcer
Interventions
ACApatch™, caregraFT™, Standard of Care
Other
Lead sponsor
Tiger Biosciences, LLC.
Industry
Eligibility
21 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Monroeville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Sep 8, 2026, 1:22 AM EDT
Not listed No phase listed Observational

Characteristics Predictive of Success and Complications in the Use of Suture-Mediated Closure of Femoral Venous Access

NCT00838175
View directory record Official record
Conditions
Cardiac Catheterization
Interventions
suture mediated closure
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 5, 2009 · Synced Sep 8, 2026, 1:22 AM EDT