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ClinicalTrials.gov public records Last synced Oct 23, 2026, 9:25 AM EDT

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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
Conditions
Chronic Low-back Pain
Interventions
Spinal Manipulation Therapy (SMT), Naloxone, Placebo, Mindfulness Based Stress Reduction Therapy (MT)
Other · Drug · Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Nashville, Tennessee
Conditions
Multiple Sclerosis, Bladder Dysfunction, Urinary Incontinence, Overactive Bladder
Interventions
Pelvic Floor Physical Therapy, Craniosacral Therapy
Procedure
Lead sponsor
CentraState Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Freehold, New Jersey
Conditions
Migraine, Migraine Disorders, Migraine With Aura, Migraine Without Aura, Migraine, Classic
Interventions
Chiropractic Treatment
Other
Lead sponsor
Harvard University Faculty of Medicine
Other
Eligibility
20 Years to 55 Years · Female only
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Neck Pain, Nurse-Patient Relations
Interventions
Combined chiropractic care and Tai Chi
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Not applicable Interventional

Chiropractic Care for Episodic Migraine

NCT06229834
Conditions
Episodic Migraine
Interventions
Chiropractic Care, Headache Health Education
Procedure · Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Otitis Media, Otitis Media Effusion, Otitis Media Recurrent, Otitis Media With Effusion in Children, Otitis Media Chronic, Otitis Media in Children, Tympanostomy Tube Insertion, Osteopathic Manipulative Treatment (OMT)
Interventions
Experimental Osteopathic Manipulative Treatment (OMT) Protocol, Control Osteopathic Manipulative Treatment (OMT) Protocol
Other
Lead sponsor
Sarah Vidal
Other
Eligibility
6 Months to 6 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Lynchburg, Virginia
Completed Not applicable Interventional Results available

Electrophysiologic Studies of Cognition in Epilepsy Patients

NCT05769634
Conditions
Drug-resistant Epilepsy
Interventions
Stereoelectroencephalography
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Conditions
Asthma
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
Des Moines University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Des Moines, Iowa
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Raised End-Tidal pCo2 on Choroidal Volume

NCT06275308
Conditions
Intraocular Pressure
Interventions
Ventilation manipulation
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
Up to 8 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Stroke, Motor Dysfunction, Chronic Stroke, Ischemic Stroke
Interventions
HBOT and OMT
Combination Product
Lead sponsor
Abington Memorial Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Abington, Pennsylvania
Conditions
Emphysema
Interventions
osteopathic manipulative treatment
Procedure
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2002
U.S. locations
1
States / cities
Kirksville, Missouri
Conditions
Respiratory Function Impaired
Interventions
Osteopathic Manipulative Medicine, Sham
Other
Lead sponsor
Jayla Bostic
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Conditions
Neck Pain, Chronic Pain
Interventions
Chiropractic Care, Tai Chi, Enhanced Usual Care
Other
Lead sponsor
Harvard University Faculty of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Conditions
Mastitis
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Western University of Health Sciences
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Pomona, California
Conditions
Post-Acute Sequelae of COVID-19
Interventions
Usual care of traditional treatment, Specific DB program/Diaphragmatic manipulation program
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Myofascial Pain Syndrome
Interventions
Multiple Component Mobile-Aid Pain Reduction Intervention, Osteopathic Manipulation Treatment, Sham Osteopathic Manipulation
Behavioral · Other
Lead sponsor
Kailea Manning
Other
Eligibility
18 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
2
States / cities
Auburn, Alabama
Conditions
Schizophrenia Disorder, Schizoaffecitve Disorder, Aggression
Interventions
Mindfulness-Based Virtual Reality Intervention
Other
Lead sponsor
Manhattan Psychiatric Center
Other
Eligibility
18 Years to 64 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
New York, New York • White Plains, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Breathe: Slow Paced Breathing to Lower Blood Pressure

NCT00328016
Conditions
High Blood Pressure
Interventions
Guided Breathing, RESPeRATE
Behavioral · Device
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
40 Years to 70 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Diabetes Mellitus, Type 2
Interventions
CBT/CMT, Control group traditional primary care
Behavioral · Other
Lead sponsor
Community Wellness Center, West Linn, OR
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
West Linn, Oregon
Terminated Not applicable Interventional Accepts healthy volunteers

Virtual Reality for External Cephalic Version

NCT03588182
Conditions
Analgesia Management for External Cephalic Version
Interventions
Virtual Reality Experience
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Conditions
Gastroesophageal Reflux Disease
Interventions
Acupuncture, Sham Acupuncture, Yoga
Procedure · Other
Lead sponsor
Midwest Biomedical Research
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Kansas City, Missouri
Conditions
Sleep Apnea Central, Cheyne-Stokes Respiration, Obstructive Sleep Apnea
Interventions
Manipulation of Positive Airway Pressure (PAP)
Other
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
3
States / cities
Denver, Colorado • Gainesville, Florida • Portage, Michigan
Conditions
Asthma
Interventions
OMT, Light touch
Procedure · Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Mayfield Heights, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Sleep and Cardiovascular Health in Adolescence

NCT03727906
Conditions
Insomnia Type; Sleep Disorder
Interventions
No pre-sleep arousal manipulation, pre-sleep arousal down-regulation, pre-sleep arousal up-regulation
Other
Lead sponsor
SRI International
Industry
Eligibility
16 Years to 20 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Menlo Park, California