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Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Vertical Sleeve Gastrectomy Clear all
Completed Not applicable Interventional

Mechanisms of Diabetes Relapse After Bariatric Surgery

NCT01516320
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Roux-en-Y Gastric Bypass, Laparoscopic adjustable gastric banding, Vertical Sleeve Gastrectomy
Procedure
Lead sponsor
Blandine Laferrere
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Sep 17, 2026, 6:58 PM EDT
Completed Phase 1Phase 2 Interventional

Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes

NCT03620773
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity, Bariatric Surgery Candidate, Nephropathy, Diabetic Kidney Disease, Diabetes Mellitus, Type 2, Diabetes Mellitus, Diabetes Complications, Weight Loss, Diabetic Nephropathies, Adolescent Obesity, Pediatric Obesity
Interventions
Aminohippurate Sodium Inj 20%, Iohexol Inj 300 mg/mL, Vertical Sleeve Gastrectomy, Renal Biopsy
Drug · Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 21 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Sep 17, 2026, 6:58 PM EDT
Active, not recruiting No phase listed Observational

Long Term Outcomes of Bariatric Patients Treated With Surgery or Endoscopy

NCT03705416
View directory record Official record
Conditions
GERD, Obesity
Interventions
Endoscopy, Surgery
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
250 participants
Timeline
2019 – 2028
U.S. locations
6
States / cities
Baltimore, Maryland • New Hyde Park, New York • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 17, 2026, 6:58 PM EDT
Terminated Not applicable Interventional

Sleeve Gastrectomy Versus Medical Management for Remission of Diabetes in Mild to Moderately Obese Patients

NCT00965302
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
Laparoscopic sleeve gastrectomy, Intensive medical management
Procedure · Behavioral
Lead sponsor
59th Medical Wing
Federal
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Sep 17, 2026, 6:58 PM EDT
Recruiting Not applicable Interventional

Vertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic Steatohepatitis

NCT03587831
View directory record Official record
Conditions
NASH - Nonalcoholic Steatohepatitis
Interventions
Vertical Sleeve Gastrectomy, Lifestyle Modification Counseling
Procedure · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
30 Years to 70 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
4
States / cities
San Francisco, California • Baton Rouge, Louisiana • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 17, 2026, 6:58 PM EDT
Completed Not applicable Interventional

Endoscopic Gastric Mucosal Devitalization (GMD) as a Primary Obesity Therapy

NCT03526263
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity; Endocrine, Bariatric Surgery Candidate
Interventions
Gastric mucosal devitalization
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
28 Years to 60 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 23, 2019 · Synced Sep 17, 2026, 6:58 PM EDT
Completed Not applicable Interventional

Endoscopic Gastric Mucosal Devitalization (GMD) as a Primary Obesity Therapy - Part 2

NCT03638843
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity; Endocrine, Bariatric Surgery Candidate
Interventions
Gastric mucosal devitalization
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
28 Years to 60 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 19, 2021 · Synced Sep 17, 2026, 6:58 PM EDT
Completed Phase 4 Interventional Results available

Apixaban Pharmacokinetics in Bariatric Patients (APB)

NCT02406885
View directory record Official record
Conditions
Bariatric Surgery, Obesity
Interventions
Apixaban
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Sep 17, 2026, 6:58 PM EDT
Active, not recruiting Not applicable Interventional

Hepatic Energy Fluxes in NASH and NAS Patients

NCT03997422
View directory record Official record
Conditions
NASH - Nonalcoholic Steatohepatitis, NAS, Overweight or Obesity, Weight Loss, Bariatric Surgery Candidate
Interventions
Vertical Sleeve Gastrectomy (VSG)
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
40 Years to 67 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 17, 2026, 6:58 PM EDT
Withdrawn Not applicable Interventional

Randomized Prospective Trial: Single Port Laparoscopic Vertical Sleeve Gastrectomy Versus Conventional Five Port Laparoscopic Vertical Sleeve Gastrectomy Surgery

NCT01401426
View directory record Official record
Conditions
Obesity, Nutrition Disorders, Body Weight
Interventions
Laparoscopic vertical sleeve gastrectomy
Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 18, 2016 · Synced Sep 17, 2026, 6:58 PM EDT
Active, not recruiting No phase listed Observational

Effects of Weight Loss Surgery on Bone Health in Adolescents

NCT02557438
View directory record Official record
Conditions
Obesity, Surgery
Interventions
Roux-en-Y Gastric Bypass, Vertical Sleeve Gastrectomy
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
13 Years to 25 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Sep 17, 2026, 6:58 PM EDT
Completed Phase 1 Interventional

RYGB and the Gastric Adipose Axis

NCT01474785
View directory record Official record
Conditions
Obesity
Interventions
human ghrelin, very low calorie diet, Hyperinsulinemic/Euglycemic Clamp
Drug · Other · Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 20, 2018 · Synced Sep 17, 2026, 6:58 PM EDT
Withdrawn Phase 2 Interventional

Medications After Adolescent Bariatric Surgery

NCT04572217
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Topiramate, Phentermine
Drug
Lead sponsor
Janey Pratt
Other
Eligibility
12 Years to 25 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Sep 17, 2026, 6:58 PM EDT
Completed No phase listed Observational

Glucose Homeostasis Pre and Post Bariatric Surgery

NCT00981500
View directory record Official record
Conditions
Morbid Obesity
Interventions
gastric bypass, gastric banding, sleeve gastrectomy
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
20 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 9, 2018 · Synced Sep 17, 2026, 6:58 PM EDT
Recruiting Phase 3 Interventional

Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient

NCT04268849
View directory record Official record
Conditions
Iron Deficiency Anemia
Interventions
Ferumoxytol, Saline, Ferrous sulfate tablets, Vitamin C
Drug
Lead sponsor
Auerbach Hematology Oncology Associates P C
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Sep 17, 2026, 6:58 PM EDT
Terminated Phase 1 Interventional Results available

Orthostatic Intolerance After Bariatric Surgery

NCT03808740
View directory record Official record
Conditions
Orthostatic Intolerance
Interventions
Atomoxetine, Placebo
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Sep 17, 2026, 6:58 PM EDT
Enrolling by invitation No phase listed Observational

Physiologic and Functional Adaptations of Insulin Sensitive Tissues

NCT03407833
View directory record Official record
Conditions
Diabetes, Insulin Resistance, Obesity, Bariatric Surgery Candidate, Roux-en-y Gastric Bypass, Liver Diseases
Interventions
Endoscopy biopsy, Surgical biopsy, Mixed-meal tolerance test, Excised Liver Tissue Sampling
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 17, 2026, 6:58 PM EDT
Completed No phase listed Observational

Small Bowel Length and Bariatric Surgery Outcomes

NCT02872493
View directory record Official record
Conditions
Malnutrition, Obesity, Weight Loss, Micronutrient Deficiency
Interventions
Small bowel length measurement
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Sep 17, 2026, 6:58 PM EDT
Active, not recruiting Phase 4 Interventional

Surgical or Medical Treatment

NCT04128995
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Pediatric Obesity, Bariatric Surgery Candidate
Interventions
Advanced Medical Therapy and Bariatric Surgery, Advanced Medical Therapy, Bariatric Surgery
Procedure · Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
13 Years to 19 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
3
States / cities
Aurora, Colorado • Chicago, Illinois • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 17, 2026, 6:58 PM EDT
Not listed Not applicable Interventional

The S.L.I.M.M.S. Procedure for Severe Clinical Obesity

NCT04592601
View directory record Official record
Conditions
Morbid Obesity, Metabolic Syndrome, Type2 Diabetes, Insulin Resistance
Interventions
S.L.I.M.M.S. Procedure
Procedure
Lead sponsor
The N.E.W. Program
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Newport Beach, California • Tustin, California
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 17, 2026, 6:58 PM EDT
Completed Phase 1 Interventional

Effect of Ghrelin on Glucose Metabolism After Bariatric Surgery

NCT02953587
View directory record Official record
Conditions
Obesity
Interventions
Oral Glucose Tolerance Test (OGTT), Human Ghrelin, Saline
Procedure · Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 17, 2026, 6:58 PM EDT
Recruiting No phase listed Observational

Gut Microbiota in Metabolic Surgery

NCT05000996
View directory record Official record
Conditions
Bariatric Surgery Candidate, Cardiovascular Diseases, Type 2 Diabetes, Dyslipidemias, Hypertension, Morbid Obesity
Interventions
Bariatric Surgery
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2035
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 17, 2026, 6:58 PM EDT
Recruiting Not applicable Interventional

Mechanistic and Clinical Outcomes of a Surgical Innovation Aimed at Minimizing GERD Associated With VSG (INNOVATE-VSG)

NCT06783751
View directory record Official record
Conditions
Obesity, Bariatric Surgery, Sleeve Gastrectomy, Gastroesophageal Reflux Disease
Interventions
Modified Vertical Sleeve Gastrectomy (mVSG), Conventional Vertical Sleeve Gastrectomy (cVSG)
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Orange, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 17, 2026, 6:58 PM EDT