- Conditions
- Tobacco Use Disorder
- Interventions
- Very low nicotine content cigarettes
- Other
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 18 Years to 44 Years · Female only
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2024
- U.S. locations
- 2
- States / cities
- Lexington, Kentucky • Burlington, Vermont
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 25–37
of 37
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Tobacco Dependence
- Interventions
- Very low nicotine content cigarettes, Normal nicotine content cigarettes
- Drug
- Lead sponsor
- Milton S. Hershey Medical Center
- Other
- Eligibility
- 21 Years to 60 Years
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Hershey, Pennsylvania
- Conditions
- Tobacco Use
- Interventions
- SPECTRUM cigarettes, usual brand of Cigarettes
- Drug · Other
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 49 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Smoking, Cigarette, Electronic Cigarettes
- Interventions
- Spectrum Research Cigarettes
- Behavioral
- Lead sponsor
- Brown University
- Other
- Eligibility
- 15 Years to 20 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Tobacco Dependence
- Interventions
- Normal Nicotine Content research cigarettes, High Nicotine e-cigarette, Very Low Nicotine Content research cigarettes, Zero Nicotine e-cigarette
- Other
- Lead sponsor
- Milton S. Hershey Medical Center
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 88 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Hershey, Pennsylvania
- Conditions
- Cigarette Smoking, E-cigarette Use
- Interventions
- Nicotine Content, Illegal cigarette price, E-cigarette price
- Behavioral
- Lead sponsor
- Virginia Polytechnic Institute and State University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Roanoke, Virginia
- Conditions
- Tobacco Smoking, Nicotine Dependence
- Interventions
- Very Low Nicotine Content Cigarettes, Normal Nicotine Content Cigarettes
- Drug
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 799 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2023
- U.S. locations
- 6
- States / cities
- San Francisco, California • Minneapolis, Minnesota • Durham, North Carolina + 3 more
- Conditions
- Cigarette Smoking
- Interventions
- Nicotine Patch, SPECTRUM Nicotine Research Cigarettes (0.07 mg), MCE-
- Drug · Behavioral
- Lead sponsor
- Francis McClernon, Ph.D.
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 87 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Tobacco Use Disorder
- Interventions
- Very low nicotine content cigarettes
- Other
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 18 Years to 44 Years · Female only
- Enrollment
- 775 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2019
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland • Burlington, Vermont
- Conditions
- Cigarette Smoking-Related Carcinoma, Tobacco-Related Carcinoma
- Interventions
- Cigarette, Nicotine Replacement, Questionnaire Administration, Survey Administration, Very Low Nicotine Content Cigarette, ECIG-Hi, ECIG-Lo
- Drug · Other · Device
- Lead sponsor
- M.D. Anderson Cancer Center
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 213 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2025
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Tobacco Dependence
- Interventions
- very low nicotine content cigarettes
- Other
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 839 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 9
- States / cities
- San Francisco, California • Tampa, Florida • Baltimore, Maryland + 6 more
- Conditions
- Tobacco Use Disorder
- Interventions
- Varying the nicotine content of cigarettes, E-Cigarettes
- Other
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 21 Years to 44 Years · Female only
- Enrollment
- 326 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland • Burlington, Vermont
- Conditions
- Smoking Cessation
- Interventions
- X-22 Smoking Cessation Product, Active Control Cigarettes
- Drug
- Lead sponsor
- 22nd Century Limited, LLC
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 234 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 3
- States / cities
- Sacramento, California • Metairie, Louisiana • Austin, Texas