Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 16, 2026, 11:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 52 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Engagement and Aging Mind

NCT05924490
Conditions
Age-related Cognitive Decline
Interventions
Real-time strategy-based videogame training, Semantic Knowledge training
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
50 Years and older
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Results available

The SOLVE-IT National Randomized Trial

NCT00653991
Conditions
HIV Infections
Interventions
SOLVE-IT
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 24 Years · Male only
Enrollment
2,020 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Smoking Cessation, Smoking, Tobacco, Mental Illness, Tobacco Use Disorder
Interventions
Videogame-based physical activity, Sedentary videogame, Bupropion, Counseling
Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
San Francisco, California
Completed Not applicable Interventional Accepts healthy volunteers

Cybercycling for Cognitive Health

NCT01167400
Conditions
Cognitive Ability, General
Interventions
Cybercycling, Traditional exercise
Behavioral
Lead sponsor
Union College, New York
Other
Eligibility
50 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
8
States / cities
Colonie, New York • Malta, New York • Niskayuna, New York + 2 more
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

An Augmented Reality Videogame for Alcohol Use Prevention and Harm Reduction in Teens

NCT04351958
Conditions
Alcohol Prevention, Harm Reduction
Interventions
Experimental: Augmented Reality ("No Time Wasted")
Behavioral
Lead sponsor
Yale University
Other
Eligibility
16 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

A Virtual Reality Game to Prevent E-cigarette and Cannabis Vaping

NCT07413432
Conditions
Cannabis, Vaping, Emotion Regulation
Interventions
Virtual reality videogame intervention for vaping prevention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
11 Years to 15 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
New Haven, Connecticut
Recruiting Not applicable Interventional Accepts healthy volunteers

Unilateral M1 Anodal tDCS to Enhance Learning in a Gross Movement Videogame Task

NCT07447882
Conditions
Motor Activity
Interventions
tDCS
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 45 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
AKL-T01
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
8 Years to 12 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Rafael, California
Not listed Not applicable Interventional Accepts healthy volunteers

EndeavorOTC® Research Study in College Students

NCT06376032
Conditions
Attention, Cognition, University Students
Interventions
EndeavorOTC®
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Cheektowaga, New York • Putney, Vermont
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Active Neurofeedback, Sham neurofeedback
Device
Lead sponsor
L. Eugene Arnold
Other
Eligibility
6 Years to 12 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Columbus, Ohio
Withdrawn Not applicable Interventional Accepts healthy volunteers

Toolkit for Experiential Well-beiNg in Dementia (TEND)

NCT06257563
Conditions
Dementia, Alzheimer Disease
Interventions
Isle of TEND Intervention
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

The Evaluation of a School Climate Videogame Intervention

NCT04025294
Conditions
Cognitive Reappraisal, Self Efficacy
Interventions
videogame, School Climate Assessment Survey
Device · Behavioral
Lead sponsor
Yale University
Other
Eligibility
14 Years to 19 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

Formative Research for an HIV Videogame for Young Black Women

NCT02685410
Conditions
HIV Prevention, STI Prevention
Interventions
One Night Stan Prototype
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 24 Years · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

Combining Entertainment & Influenza Education for Pediatric Patients

NCT01788514
Conditions
Influenza
Interventions
Videogame
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
8 Years to 17 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Mineola, New York
Conditions
Smoking
Interventions
smokeSCREEN video game
Device
Lead sponsor
Yale University
Other
Eligibility
11 Years to 14 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
3
States / cities
Hamden, Connecticut • New Haven, Connecticut
Active, not recruiting No phase listed Observational

EndeavorOTC™ Prospective Product Registry

NCT06109051
Conditions
ADHD
Interventions
EndeavorOTC
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
Not listed
Enrollment
198 participants
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Triggers and Responses to Simulator Sickness in Videogame Players

NCT02122354
Conditions
Simulator Sickness
Interventions
"Hide and Seek" videogame
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Digital Intervention for HIV Prevention in Black Adolescent Girls

NCT04108988
Conditions
HIV, Risk Reduction Behavior
Interventions
InvestiDate, Non-Health Related Video Game
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
14 Years to 18 Years · Female only
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Executive Dysfunction, Depression, Stroke
Interventions
AKL-T01, Metacognitive Strategy Training
Device · Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
50 Years to 79 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Contraceptive Usage, Contraception Behavior
Interventions
Videogame Intervention, Commercial game control
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
15 Years to 20 Years
Enrollment
850 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
7
States / cities
Brooklyn, New York • New York, New York • Queens, New York + 2 more
Conditions
Anger, Aggression
Interventions
ACT, ACT with RAGE-Control
Behavioral
Lead sponsor
Gonzalez-Heydrich, Joseph, M.D.
Individual
Eligibility
10 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

Video Game Play to Alleviate Adolescent Anxiety

NCT05923944
Conditions
Anxiety, Anxiety Disorders and Symptoms
Interventions
Eco-Rescue, Bejelewed 3
Behavioral
Lead sponsor
School of Health Sciences Geneva
Other
Eligibility
11 Years to 15 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Miami, Florida
Not listed Not applicable Interventional Accepts healthy volunteers

Examining the Impacts on In-School Behaviors of In-Home Videogame Play

NCT05260398
Conditions
Emotional Regulation, Problem Behavior, Irritable Mood
Interventions
Mightier Online Gameplay
Behavioral
Lead sponsor
Neuromotion Labs
Industry
Eligibility
6 Years to 11 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Boston, Massachusetts