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Showing 1–24 of 51 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Videogame Clear all
Completed Not applicable Interventional Results available

The SOLVE-IT National Randomized Trial

NCT00653991
View directory record Official record
Conditions
HIV Infections
Interventions
SOLVE-IT
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 24 Years · Male only
Enrollment
2,020 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Sep 1, 2026, 10:18 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Videogame-based Incentives for Smoking Cessation

NCT01761760
View directory record Official record
Conditions
Smoking Cessation
Interventions
Videogame-based smoking cessation intervention
Behavioral
Lead sponsor
Rowan University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Glassboro, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Exercise Videogames for Physical Activity Adoption and Maintenance

NCT03298919
View directory record Official record
Conditions
Physical Activity
Interventions
Exercise Video Games, Aerobic Exercise, Home exercise videogames, Home Standard Exercise
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
283 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 24, 2019 · Synced Sep 1, 2026, 10:18 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Toolkit for Experiential Well-beiNg in Dementia (TEND)

NCT06257563
View directory record Official record
Conditions
Dementia, Alzheimer Disease
Interventions
Isle of TEND Intervention
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Digital Intervention to Prevent the Initiation of Opioid Misuse in Adolescents in School-based Health Centers

NCT04941950
View directory record Official record
Conditions
Opioid Misuse
Interventions
PlaySmart, Video Game Control
Behavioral · Other
Lead sponsor
Tyra Boomer
Other
Eligibility
16 Years to 19 Years
Enrollment
533 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
15
States / cities
Bridgeport, Connecticut • Durham, Connecticut • East Hartford, Connecticut + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 1, 2026, 10:18 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness Testing of a Videogame Intervention (No Baby No) to Decrease Contraception Non-use Among Adolescents.

NCT06990724
View directory record Official record
Conditions
Contraceptive Usage, Contraception Behavior
Interventions
Videogame Intervention, Commercial game control
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
15 Years to 20 Years
Enrollment
850 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
7
States / cities
Brooklyn, New York • New York, New York • Queens, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 1, 2026, 10:18 PM EDT
Not listed Not applicable Interventional

RAGE-Control: Teaching Emotional Self-regulation Through Videogame Play

NCT03270813
View directory record Official record
Conditions
Anger, Aggression
Interventions
Relaxation training plus RAGE-Control, Relaxation training plus Sham Videogame
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
7 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 6, 2020 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Triggers and Responses to Simulator Sickness in Videogame Players

NCT02122354
View directory record Official record
Conditions
Simulator Sickness
Interventions
"Hide and Seek" videogame
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Sep 1, 2026, 10:18 PM EDT
Terminated Not applicable Interventional

Cognitive Motor Therapy Applications Using Videogame Platform

NCT02256007
View directory record Official record
Conditions
Stroke
Interventions
Paper and Pencil Assessments
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Sep 1, 2026, 10:18 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Unilateral M1 Anodal tDCS to Enhance Learning in a Gross Movement Videogame Task

NCT07447882
View directory record Official record
Conditions
Motor Activity
Interventions
tDCS
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 45 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Evaluation of a School Climate Videogame Intervention

NCT04025294
View directory record Official record
Conditions
Cognitive Reappraisal, Self Efficacy
Interventions
videogame, School Climate Assessment Survey
Device · Behavioral
Lead sponsor
Yale University
Other
Eligibility
14 Years to 19 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sensitivity of Project: EVO Monitor Cognitive Measurements to Pharmacological Agents

NCT02822937
View directory record Official record
Conditions
Healthy
Interventions
Methylphenidate, Triazolam, Project: EVO, Placebo
Drug · Other
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
40 Years to 55 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 6, 2016 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional

Examining the Effects of Video-game Exercise on Mobility and Brain Plasticity in Individuals With Multiple Sclerosis

NCT01780792
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Dance Dance Revolution video game play
Other
Lead sponsor
Ohio State University
Other
Eligibility
30 Years to 59 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 6, 2017 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Implementation and Dissemination of an Evidence-Based Tobacco Product Use Prevention Videogame Intervention With Adolescents

NCT03815591
View directory record Official record
Conditions
Smoking Cessation, Smoking
Interventions
smokeSCREEN web-based game
Device
Lead sponsor
Yale University
Other
Eligibility
10 Years to 16 Years
Enrollment
560 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of a Videogame Prototype Targeting Cigarette and Marijuana Smoking, and Tobacco Product Prevention Among Young Adolescents (smokeScreen)

NCT03722888
View directory record Official record
Conditions
Smoking
Interventions
smokeSCREEN video game
Device
Lead sponsor
Yale University
Other
Eligibility
11 Years to 14 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
3
States / cities
Hamden, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 28, 2018 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of a Videogame Prototype Targeting Cigarette and Marijuana Smoking, and Tobacco Product Prevention Among Young Adolescents

NCT03107936
View directory record Official record
Conditions
Smoking
Interventions
smokeSCREEN game
Behavioral
Lead sponsor
Yale University
Other
Eligibility
10 Years to 16 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
4
States / cities
Hamden, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 18, 2018 · Synced Sep 1, 2026, 10:18 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

EndeavorOTC® Research Study in College Students

NCT06376032
View directory record Official record
Conditions
Attention, Cognition, University Students
Interventions
EndeavorOTC®
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Cheektowaga, New York • Putney, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional

Augmenting Patching Treatment for Amblyopia With Physical Exercise

NCT03822806
View directory record Official record
Conditions
Amblyopia
Interventions
Physical Exercise in addition to Patching
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
5 Years to 16 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Sep 1, 2026, 10:18 PM EDT
Recruiting Not applicable Interventional

Self-Administered Gaming and Exercise at Home (SAGEH)

NCT05929027
View directory record Official record
Conditions
Stroke, Hand Weakness
Interventions
NoNo, occupational therapy - self directed
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Exergaming: A Research Study Testing a Videogame Intervention to Increase Physical Activity for Families

NCT00889122
View directory record Official record
Conditions
Obesity
Interventions
Exergame (DDR)
Behavioral
Lead sponsor
MaineHealth
Other
Eligibility
9 Years to 17 Years
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Scarborough, Maine
Source: ClinicalTrials.gov public record
Updated Aug 3, 2010 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional

Software Treatments for Actively Reducing Severity of Cognitive Deficits in MDD (STARS-MDD)

NCT03310281
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
HOLD: Videogame
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
25 Years to 55 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Garden Grove, California • North Miami, Florida • Charleston, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Virtual Reality Game to Prevent E-cigarette and Cannabis Vaping

NCT07413432
View directory record Official record
Conditions
Cannabis, Vaping, Emotion Regulation
Interventions
Virtual reality videogame intervention for vaping prevention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
11 Years to 15 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 1, 2026, 10:18 PM EDT
Not listed Not applicable Interventional

Anger Control Therapy (ACT) With RAGE-Control: An Outpatient Videogame-assisted Therapy for the Treatment of Anger

NCT01551732
View directory record Official record
Conditions
Anger, Aggression
Interventions
ACT, ACT with RAGE-Control
Behavioral
Lead sponsor
Gonzalez-Heydrich, Joseph, M.D.
Individual
Eligibility
10 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2020 · Synced Sep 1, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Combining Entertainment & Influenza Education for Pediatric Patients

NCT01788514
View directory record Official record
Conditions
Influenza
Interventions
Videogame
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
8 Years to 17 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Sep 1, 2026, 10:18 PM EDT