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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Videogame Intervention Clear all
Completed Not applicable Interventional Accepts healthy volunteers

A Virtual Reality Game to Prevent E-cigarette and Cannabis Vaping

NCT07413432
View directory record Official record
Conditions
Cannabis, Vaping, Emotion Regulation
Interventions
Virtual reality videogame intervention for vaping prevention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
11 Years to 15 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Combining Entertainment & Influenza Education for Pediatric Patients

NCT01788514
View directory record Official record
Conditions
Influenza
Interventions
Videogame
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
8 Years to 17 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Results available

Software Treatment for Actively Reducing Severity of ADHD - Follow Up

NCT02828644
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity
Interventions
EVO
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
8 Years to 12 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
15
States / cities
Scottsdale, Arizona • Newport Beach, California • Sacramento, California + 9 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Evaluation of a School Climate Videogame Intervention

NCT04025294
View directory record Official record
Conditions
Cognitive Reappraisal, Self Efficacy
Interventions
videogame, School Climate Assessment Survey
Device · Behavioral
Lead sponsor
Yale University
Other
Eligibility
14 Years to 19 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Sep 10, 2026, 3:24 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Videogame-based Incentives for Smoking Cessation

NCT01761760
View directory record Official record
Conditions
Smoking Cessation
Interventions
Videogame-based smoking cessation intervention
Behavioral
Lead sponsor
Rowan University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Glassboro, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of a Videogame Prototype Targeting Cigarette and Marijuana Smoking, and Tobacco Product Prevention Among Young Adolescents (smokeScreen)

NCT03722888
View directory record Official record
Conditions
Smoking
Interventions
smokeSCREEN video game
Device
Lead sponsor
Yale University
Other
Eligibility
11 Years to 14 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
3
States / cities
Hamden, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 28, 2018 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Results available

Pilot Feasibility Study of Neurofeedback for Attention Deficit Hyperactivity Disorder (ADHD)

NCT00886483
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Active Neurofeedback, Sham neurofeedback
Device
Lead sponsor
L. Eugene Arnold
Other
Eligibility
6 Years to 12 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 10, 2016 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional

Cognitive Remediation in Posttraumatic Stress Disorder (PTSD)

NCT00850447
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Cognitive Remediation Therapy, Videogame
Other
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2012 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Exergaming: A Research Study Testing a Videogame Intervention to Increase Physical Activity for Families

NCT00889122
View directory record Official record
Conditions
Obesity
Interventions
Exergame (DDR)
Behavioral
Lead sponsor
MaineHealth
Other
Eligibility
9 Years to 17 Years
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Scarborough, Maine
Source: ClinicalTrials.gov public record
Updated Aug 3, 2010 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interactive Digital Intervention to Prevent Violence Among Young Adults

NCT03820609
View directory record Official record
Conditions
Sexual Assault
Interventions
Digital Intervention
Behavioral
Lead sponsor
Happy People Games, LLC
Other
Eligibility
18 Years to 24 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
2
States / cities
Warwick, Rhode Island • Clemson, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 2, 2019 · Synced Sep 10, 2026, 3:24 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Toolkit for Experiential Well-beiNg in Dementia (TEND)

NCT06257563
View directory record Official record
Conditions
Dementia, Alzheimer Disease
Interventions
Isle of TEND Intervention
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Sep 10, 2026, 3:24 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

An Augmented Reality Videogame for Alcohol Use Prevention and Harm Reduction in Teens

NCT04351958
View directory record Official record
Conditions
Alcohol Prevention, Harm Reduction
Interventions
Experimental: Augmented Reality ("No Time Wasted")
Behavioral
Lead sponsor
Yale University
Other
Eligibility
16 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Interactive Game for HIV Prevention in Early Adolescents

NCT01666496
View directory record Official record
Conditions
HIV, Risk Reduction
Interventions
Experimental Video Game, Off the Shelf Video Game
Behavioral
Lead sponsor
Yale University
Other
Eligibility
11 Years to 14 Years
Enrollment
333 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Virtual Reality Videogame for E-cigarette Prevention in Teens

NCT04054765
View directory record Official record
Conditions
E-Cig Use, Vaping
Interventions
videogame, treatment as usual
Device · Other
Lead sponsor
Yale University
Other
Eligibility
11 Years to 17 Years
Enrollment
287 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Milford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 24, 2021 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional

Software Treatments for Actively Reducing Severity of Cognitive Deficits in MDD (STARS-MDD)

NCT03310281
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
HOLD: Videogame
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
25 Years to 55 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Garden Grove, California • North Miami, Florida • Charleston, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Results available

Software Treatment for Actively Reducing Severity of ADHD

NCT02674633
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity
Interventions
AKL-T01, AKL-T09
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
8 Years to 12 Years
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
20
States / cities
Dothan, Alabama • Scottsdale, Arizona • Newport Beach, California + 17 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Technology Based Obesity Prevention Project (TeBOPP)

NCT01981434
View directory record Official record
Conditions
Obesity in Children
Interventions
Video game based obesity education
Other
Lead sponsor
Valleywise Health
Other
Eligibility
8 Years to 15 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 28, 2019 · Synced Sep 10, 2026, 3:24 AM EDT
Recruiting Phase 2 Interventional

A Digital Intervention for Post-Stroke Depression and Executive Dysfunction

NCT05507138
View directory record Official record
Conditions
Executive Dysfunction, Depression, Stroke
Interventions
AKL-T01, Metacognitive Strategy Training
Device · Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
50 Years to 79 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Formative Research for an HIV Videogame for Young Black Women

NCT02685410
View directory record Official record
Conditions
HIV Prevention, STI Prevention
Interventions
One Night Stan Prototype
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 24 Years · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 12, 2017 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inspired: Smartphone Videogame-Based Smoking Cessation Intervention

NCT03929003
View directory record Official record
Conditions
Smoking Cessation
Interventions
Inspired
Behavioral
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Glassboro, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 9, 2020 · Synced Sep 10, 2026, 3:24 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Examining the Impacts on In-School Behaviors of In-Home Videogame Play

NCT05260398
View directory record Official record
Conditions
Emotional Regulation, Problem Behavior, Irritable Mood
Interventions
Mightier Online Gameplay
Behavioral
Lead sponsor
Neuromotion Labs
Industry
Eligibility
6 Years to 11 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Sep 10, 2026, 3:24 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness Testing of a Videogame Intervention (No Baby No) to Decrease Contraception Non-use Among Adolescents.

NCT06990724
View directory record Official record
Conditions
Contraceptive Usage, Contraception Behavior
Interventions
Videogame Intervention, Commercial game control
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
15 Years to 20 Years
Enrollment
850 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
7
States / cities
Brooklyn, New York • New York, New York • Queens, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 10, 2026, 3:24 AM EDT
Not listed Not applicable Interventional

RAGE-Control: Teaching Emotional Self-regulation Through Videogame Play

NCT03270813
View directory record Official record
Conditions
Anger, Aggression
Interventions
Relaxation training plus RAGE-Control, Relaxation training plus Sham Videogame
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
7 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 6, 2020 · Synced Sep 10, 2026, 3:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Digital Intervention for HIV Prevention in Black Adolescent Girls

NCT04108988
View directory record Official record
Conditions
HIV, Risk Reduction Behavior
Interventions
InvestiDate, Non-Health Related Video Game
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
14 Years to 18 Years · Female only
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Sep 10, 2026, 3:24 AM EDT