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Conditions: Maternal Stress
Interventions: Vitamin D (Cholecalciferol ), Placebo; Dietary Supplement · Other
Lead sponsor: University of Idaho; Other
Eligibility: 18 Years to 64 Years · Female only
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Coeur d'Alene, Idaho • Moscow, Idaho

Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: Vitamin D (cholecalciferol), Placebo; Dietary Supplement
Lead sponsor: Minneapolis Veterans Affairs Medical Center; Federal
Eligibility: 40 Years and older
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Bone Alteration, Dietary Modification
Interventions: Calcium/Vitamin D, Placebo; Dietary Supplement
Lead sponsor: United States Army Research Institute of Environmental Medicine; Federal
Eligibility: 17 Years to 42 Years
Enrollment: 175 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Osteopenia
Interventions: bisphosphonate therapy (risedronate), Vitamin D supplement, Calcium; Drug · Dietary Supplement
Lead sponsor: State University of New York - Upstate Medical University; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2008
U.S. locations: 1
States / cities: Syracuse, New York

Conditions: Postmenopausal Osteoporosis
Interventions: Dried Plum, Calcium supplement, Vitamin D supplement; Dietary Supplement
Lead sponsor: Penn State University; Other
Eligibility: 55 Years to 75 Years · Female only
Enrollment: 322 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2027
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Impaired Fasting Glucose, Impaired Glucose Tolerance, Vitamin D Insufficiency
Interventions: Placebo, 50K vitamin D2; Drug
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 35 Years to 85 Years · Male only
Enrollment: 205 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Anxiety, Stress, Memory Deficits, Cortisol Overproduction
Interventions: Heights Smart Supplement; Dietary Supplement
Lead sponsor: Heights; Industry
Eligibility: 21 Years to 70 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Vitamin D Deficiency
Interventions: 400 IU Vitamin D3 (cholecalciferol), 2400 IU Vitamin D3 (cholecalciferol), 6400 IU Vitamin D3 (cholecalciferol); Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 460 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2012
U.S. locations: 2
States / cities: Rochester, New York • Charleston, South Carolina

Conditions: Frailty
Interventions: Supervised aerobic + resistance training and nutritional support; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Osteoporosis, Osteopenia
Interventions: Nitroglycerin ointment, Calcium supplement with vitamin D; Drug
Lead sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS); NIH
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2007
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Eye Health, Vision, Cognitive Function
Interventions: VisionPure Dietary Supplement, Placebo; Dietary Supplement
Lead sponsor: Applied Science & Performance Institute; Industry
Eligibility: 18 Years to 40 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 3
States / cities: Lutz, Florida • Tampa, Florida

Conditions: Vitamin D Deficiency, Falls
Interventions: 200 IU/d cholecalciferol, 1000 IU/d cholecalciferol, 2000 IU/d cholecalciferol, 4000 IU/d cholecalciferol; Dietary Supplement
Lead sponsor: Johns Hopkins University; Other
Eligibility: 70 Years and older
Enrollment: 688 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 2
States / cities: Baltimore, Maryland • Hagerstown, Maryland

Conditions: Accidental Fall
Interventions: Gait and balance assessment, Medication review, Comorbidity review, Fall history, Assessment of feet/footwear, Assessment of visual acuity, Home safety risk assessment, Vitamin D Deficiency; Behavioral
Lead sponsor: National Opinion Research Center; Other
Eligibility: 65 Years and older
Enrollment: 780 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Prostate Adenocarcinoma
Interventions: Cholecalciferol, Laboratory Biomarker Analysis, Patient Observation, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration; Dietary Supplement · Other · Drug
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years and older · Male only
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2020
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Prostate Cancer, Vitamin D Deficiency, Stress Reaction
Interventions: cholecalciferol, Standard of Care Prostate Biopsy - collection of 13th core for RNA-seq, Standard of Care Prostate Biopsies at baseline and after one year vitamin D3 supplementation, Allostatic Load; Drug · Procedure · Diagnostic Test
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 50 Years to 75 Years · Male only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Polycystic Ovary Syndrome, Premenstrual Syndrome
Interventions: Female Hormone Balance Supplement; Dietary Supplement
Lead sponsor: Rael; Industry
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Sarcopenia
Interventions: Exercise Intervention, Supplement Intervention; Other · Dietary Supplement
Lead sponsor: Tufts University; Other
Eligibility: 70 Years and older
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Nonalcoholic Fatty Liver
Interventions: Vitamind D; Dietary Supplement
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Center-involved Diabetic Macular Edema (CI-DME)
Interventions: Diabetes Visual Function Study (DiVFuSS) softgels, canola oil placebo softgels, 2 per day; Dietary Supplement · Other
Lead sponsor: ZeaVision, LLC; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Olympia, Washington • Tacoma, Washington

Conditions: Hot Flushes, Menopause, Premature, Obesity, Vitamin D Deficiency
Interventions: Vitamin D, Placebo; Dietary Supplement · Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 40 Years to 60 Years · Female only
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Hypovitaminosis D, Insulin Resistance, Diabetes
Interventions: Vitamin D3; Dietary Supplement
Lead sponsor: Bastyr University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 2
States / cities: Kailua-Kona, Hawaii • Kenmore, Washington

Conditions: Nutrient Deficiency, Happiness, Digestive Health, Vulnerability to Disease, Mood Swings, Energy
Interventions: Alii Supplement; Dietary Supplement
Lead sponsor: Texas Christian University; Other
Eligibility: 18 Years to 25 Years · Female only
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Colorectal Cancer
Interventions: cholecalciferol, polymerase chain reaction, polymorphism analysis, protein expression analysis, reverse transcriptase-polymerase chain reaction, western blotting, high performance liquid chromatography, laboratory biomarker analysis, pharmacological study, adjuvant therapy, immunoscintigraphy; Dietary Supplement · Genetic · Other + 1 more
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years to 120 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Vitamin D Deficiency
Interventions: Oral Vitamin D3, Ultraviolet Light; Dietary Supplement · Radiation
Lead sponsor: Rockefeller University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 118 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: New York, New York

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Impact of Vitamin D Supplements on Mental Health and Milk Composition in Mothers Living in Idaho

Effect of Supplemental Vitamin D on Skeletal Muscle Function in Chronic Obstructive Pulmonary Disease (COPD) Patients

Efficacy of a Once Daily Calcium and Vitamin D Fortified Food Product to Improve Bone Microarchitecture

Study of Adults With Low Growth Hormone Who Survived Childhood Cancer Where Treatment Caused Low Bone Density

Dried Plums and Bone Health in Postmenopausal Women

D Vitamin Intervention in VA

An Exploratory Investigation of a Supplement to Promote Cognitive Health Benefits

Establishing the Vitamin D Requirements During Lactation

Prehabilitation of Veterans With Exercise and Nutrition

Nitroglycerin Ointment for Preventing Bone Loss in Postmenopausal Women

The Effects of VisionPure™ on Indices of Vision Health and Cognitive Function

Study To Understand Fall Reduction and Vitamin D in You

Evaluating the Cost Effectiveness of STEADI

Cholecalciferol Supplement in Treating Patients With Localized Prostate Cancer Undergoing Observation

Vitamin D Supplementation in RNA-seq Profiles of Single-core Prostate Samples, Among Veterans

Effects of a Female Hormone Balance Supplement on Symptoms of Polycystic Ovary Syndrome and Severe Premenstrual Syndrome

Efficacy of Nutritional Supplementation on Physical-activity Mediated Changes in Physical Functioning Older Adults at Risk for Mobility Disability (The VIVE2 Study)

Vitamin D Replacement in Nonalcoholic Fatty Liver Disease

Prospective Study of Adjunctive Carotenoids Plus Anti-oxidants in Anti-VEGF Treated Diabetic Macular Edema

The Role of Vitamin D in Menopause: Relationship to Menopausal Symptoms in Body Composition

Comparative Effectiveness of Vitamin D and Repletion Strategies

Alii Supplement Study

DNA Changes That Affect Vitamin D Metabolism in Patients With Colorectal Cancer Receiving Vitamin D Supplements

The Effect of Oral Vitamin D Versus Narrow-Band UV-B Exposure on the Lipid Profile