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ClinicalTrials.gov public records Last synced Oct 15, 2026, 7:14 AM EDT

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Showing 409–432 of 553 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Vitamin D3, Cholecalciferol Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Vitamin D and Calcium on Genes in the Colon

NCT00298545
View directory record Official record
Conditions
Colorectal Polyps, Colorectal Adenoma, Adenocarcinoma
Interventions
placebo and Calcitriol, Calcium and Calcitriol
Drug
Lead sponsor
Rockefeller University
Other
Eligibility
48 Years to 72 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2011 · Synced Oct 15, 2026, 7:14 AM EDT
Recruiting Not applicable Interventional

Preserving Physical Function in Older Adults With Cancer: Impact of an Optimizing Nutrition Intervention Applied Before and After Surgery

NCT05912257
View directory record Official record
Conditions
Cancer
Interventions
Structured perioperative nutrition and exercise, Nutrition and Exercise Counseling
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Phase 4 Interventional

A Trial Evaluating Vitamin D Normalization on Major Adverse Cardiovascular-Related Events Among Myocardial Infarction Patients

NCT02996721
View directory record Official record
Conditions
Death, Myocardial Infarction, Cerebral Vascular Accident, Heart Failure Hospitalization
Interventions
Vitamin D3
Biological
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
634 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of VisionPure™ on Indices of Vision Health and Cognitive Function

NCT05533658
View directory record Official record
Conditions
Eye Health, Vision, Cognitive Function
Interventions
VisionPure Dietary Supplement, Placebo
Dietary Supplement
Lead sponsor
Applied Science & Performance Institute
Industry
Eligibility
18 Years to 40 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
3
States / cities
Lutz, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 26, 2023 · Synced Oct 15, 2026, 7:14 AM EDT
Withdrawn Phase 3 Interventional

Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Major Surgical Procedures.

NCT02138591
View directory record Official record
Conditions
Vitamin d Deficiency
Interventions
Blood draw pre-operatively, Blood draw post-operative Day 1, Blood draw post-operative Day 2
Procedure
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 16, 2017 · Synced Oct 15, 2026, 7:14 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Vitamin D Metabolism in Chronic Kidney Disease Patients

NCT01528176
View directory record Official record
Conditions
Vitamin D Metabolism is in Chronic Kidney Disease
Interventions
10,000 IU of cholecalciferol for a total of 8 weeks
Drug
Lead sponsor
Memphis VA Medical Center
Federal
Eligibility
18 Years to 85 Years · Male only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 14, 2012 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Effect of Vitamin D Statues on Endothelial Function

NCT01049048
View directory record Official record
Conditions
Cardiovascular Diseases, Vitamin D Deficiency
Interventions
Vitamin D3, Placebo
Dietary Supplement
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
55 Years to 65 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 5, 2015 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Availability of Vitamin D in Orange Juice

NCT01778114
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Vitamin D2 in orange juice, Vitamin D3 in orange juice, Vitamin D2, Vitamin D3, Placebo
Dietary Supplement · Other
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Oct 15, 2026, 7:14 AM EDT
Terminated Phase 2 Interventional Results available

Vitamin D and n-3 Polyunsaturated Fatty Acids (PUFAs) to Prevent Chronic Pain Following Major Thermal Burn Injury

NCT03313076
View directory record Official record
Conditions
Chronic Pain Following Thermal Burn Injury
Interventions
Omega-3 fatty acids (fish oil), Vitamin D3 (cholecalciferol), Vitamin D3 (cholecalciferol) placebo, Omega-3 fatty acid placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Not applicable Interventional Results available

Vitamin D Replacement After Kidney Transplant

NCT00748618
View directory record Official record
Conditions
Kidney Transplantation, Vitamin D Deficiency
Interventions
Standard vitamin D3 treatment, High dose vitamin D3 treatment
Dietary Supplement
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2023
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 26, 2024 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Efficacy of Daily Vitamin D3 Supplementation in Normal Weight Adolescents

NCT01058720
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 1, 2016 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Phase 2 Interventional

Vitamin D3 Supplementation in Participants Diagnosed With Early-Stage Prostate Cancer Who Decide to Undergo Active Surveillance Treatment Regimen.

NCT01045109
View directory record Official record
Conditions
Prostate Cancer
Interventions
cholecalciferol
Dietary Supplement
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 90 Years · Male only
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 18, 2018 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Phase 2 Interventional

Calcitriol in Treating Patients With a Rising PSA Level Following Treatment for Prostate Cancer

NCT00004043
View directory record Official record
Conditions
Prostate Cancer
Interventions
calcitriol
Dietary Supplement
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years to 120 Years · Male only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2003
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 28, 2017 · Synced Oct 15, 2026, 7:14 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

A Randomized Control Trial of Vitamin D Prophylaxis in the Prevention of Hypertensive Disorders of Pregnancy

NCT02920593
View directory record Official record
Conditions
Gestational Hypertension, Toxemia, Superimposed Preeclampsia, Eclampsia, HELLP Syndrome
Interventions
Vitamin D3
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older · Female only
Enrollment
412 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Not applicable Interventional Results available

Cholecalciferol in Newly Diagnosed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia With Vitamin D Deficiency

NCT02553447
View directory record Official record
Conditions
Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, Untreated Chronic Lymphocytic Leukemia, Vitamin D Deficiency
Interventions
Cholecalciferol, Laboratory Biomarker Analysis
Dietary Supplement · Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Phase 3 Interventional Results available

Heartland Osteoporosis Prevention Study

NCT02186600
View directory record Official record
Conditions
Osteopenia
Interventions
Calcium Carbonate, Vitamin D3, Risedronate, Bone-loading exercises
Drug · Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older · Female only
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced Oct 15, 2026, 7:14 AM EDT
Terminated Phase 3 Interventional

Chemoprevention of Colorectal Adenomas

NCT00486512
View directory record Official record
Conditions
Adenomatous Polyps
Interventions
0.5 mg calcitriol (1a -25-dihydroxycholecalciferol), 75 mg acetylsalicylic acid (ASA) + 1250 mg calcium carbonate (CaCO3), placebo to 0.5 mg calcitriol (1a -25-dihydroxycholecalciferol), placebo to 75 mg acetylsalicylic acid (ASA) + 1250 mg calcium carbonate (CaCO3), Colonoscopy
Drug · Procedure
Lead sponsor
Colotech A/S
Industry
Eligibility
40 Years to 75 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
24
States / cities
Huntsville, Alabama • San Diego, California • Clearwater, Florida + 20 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Nutritional Intervention for Age-related Muscular Function and Strength Losses-Study 2

NCT02043171
View directory record Official record
Conditions
Sarcopenia
Interventions
Placebo, HMB plus Vitamin D, Non-Exercise, Exercise
Dietary Supplement · Drug · Behavioral
Lead sponsor
Metabolic Technologies Inc.
Industry
Eligibility
60 Years and older
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Ames, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Phase 2 Interventional Results available

Bone Mass and Strength After Kidney Transplantation

NCT02224144
View directory record Official record
Conditions
End Stage Renal Disease, Kidney Transplantation, Bone Loss, Fractures, Vascular Calcifications
Interventions
Vitamin D3, Calcitriol, Placebo
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2025 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Randomized Placebo-Controlled Study to Evaluate the Effects of a Gummy and Capsule Supplement on Symptoms of Premenstrual Syndrome

NCT06763809
View directory record Official record
Conditions
PMS, Menstrual Cramp, Mood Change
Interventions
PMS Capsule, Capsule Placebo, PMS Gummy, Gummy Placebo
Dietary Supplement
Lead sponsor
Semaine Health
Industry
Eligibility
18 Years and older · Female only
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 15, 2026, 7:14 AM EDT
Recruiting Early Phase 1 Interventional

Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients

NCT05045066
View directory record Official record
Conditions
Localized Prostate Carcinoma, Stage IV Prostate Cancer AJCC v8, Locally Recurrent Prostate Carcinoma, Metastatic Prostate Carcinoma
Interventions
Cholecalciferol, Quality-of-Life Assessment, Biospecimen Collection
Dietary Supplement · Other · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Male only
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2031
U.S. locations
2
States / cities
Scottsdale, Arizona • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Vitamin D and Calcium Homeostasis for Prevention of Type 2 Diabetes

NCT00436475
View directory record Official record
Conditions
Glucose Intolerance, Type 2 Diabetes Mellitus, Metabolic Syndrome
Interventions
Vitamin D3 2,000 IU orally once daily, Calcium Carbonate 400 mg orally twice daily, Vitamin D3-Placebo, Calcium-Placebo
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
40 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Vitamin D Increases Serum Levels of the Soluble Receptor for Advanced Glycation End Products in Women With PCOS

NCT03644212
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Vitamin D Deficiency
Interventions
Vitamin D3
Drug
Lead sponsor
Maimonides Medical Center
Other
Eligibility
16 Years to 48 Years · Female only
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Oct 15, 2026, 7:14 AM EDT
Completed Not applicable Interventional Results available

Improving Vitamin D Status in Home-bound Elders

NCT01410084
View directory record Official record
Conditions
Vitamin D Deficiency, Accidental Falls
Interventions
Vitamin D3, Vitamin E
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Oct 15, 2026, 7:14 AM EDT