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ClinicalTrials.gov public records Last synced Nov 13, 2026, 2:31 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 121 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Vitamin D3 - high dose Clear all

Conditions: Prostate Cancer
Interventions: calcitriol, mitoxantrone hydrochloride, prednisone; Dietary Supplement · Drug
Lead sponsor: OHSU Knight Cancer Institute; Other
Eligibility: 18 Years to 100 Years · Male only
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Ectonucleotide Pyrophosphatase/Phosphodiesterase1 Deficiency, Autosomal Recessive Hypophosphatemic Rickets, Generalized Arterial Calcification of Infancy
Interventions: INZ-701, Control Arm (Conventional Therapy); Drug
Lead sponsor: Inozyme Pharma; Industry
Eligibility: 1 Year to 12 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 3
States / cities: Chicago, Illinois • Philadelphia, Pennsylvania • Fort Worth, Texas

Conditions: Diabetes, Executive Dysfunction
Interventions: Cholecalciferol; Drug
Lead sponsor: Loyola University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Asthma, Vitamin D Deficiency
Interventions: Vitamin D2 + vitamin D3, Vitamin D3; Drug
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 8 Years to 17 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: ADHD
Interventions: Magnetic Resonance Imaging (MRI), PHNO, calcitriol, Placebo oral capsule, high-resolution research tomography, Dextro Amphetamine; Procedure · Drug · Dietary Supplement
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Cluster Headache
Interventions: Vitamin D, multivitamin, Placebo; Dietary Supplement
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 70 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Anemia of Chronic Kidney Disease
Interventions: Cholecalciferol; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 1 Year to 21 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Vitamin D Deficiency
Interventions: Vitamin D3; Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 13 Years to 20 Years
Enrollment: 183 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Hypertension, Vitamin D Deficiency, Pre-Hypertension
Interventions: Cholecalciferol; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 50 Years
Enrollment: 534 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 3
States / cities: Hartford, Connecticut • Boston, Massachusetts • Minneapolis, Minnesota

Conditions: Vitamin D Deficiency
Interventions: Treatment; Drug
Lead sponsor: Johns Hopkins All Children's Hospital; Other
Eligibility: 36 Months to 18 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: St. Petersburg, Florida

Conditions: Healthy Volunteers
Interventions: Single High Dose Cholecalciferol, Daily Dose Cholecalciferol; Dietary Supplement
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Secondary Hyperparathyroidism Due to Renal Causes, Vitamin D Insufficiency, CKD Stage 3, CKD Stage 4
Interventions: Calcifediol Oral Capsule, Calcifediol Oral Product, Cholecalciferol, Paricalcitol Oral Capsule; Drug
Lead sponsor: OPKO Health, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 3
States / cities: Garden Grove, California • Chicago, Illinois • West Bend, Wisconsin

Conditions: IBD, Ulcerative Colitis, Crohn Disease
Interventions: Vitamin D3; Drug
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 7 Years to 25 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Bone Metabolism Biomarkers, Bone Mineral Density, Physical Fitness
Interventions: Vitamin D3, Physical Activity; Drug · Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years to 99 Years · Female only
Enrollment: 191 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2026
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Bariatric Surgery
Interventions: Not listed
Lead sponsor: Texas Tech University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Lubbock, Texas

Conditions: Crohn's Disease, Vitamin D Deficiency
Interventions: Cholecalciferol 10,000 IU, Cholecalciferol 400 IU; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 75 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 4
States / cities: Indianapolis, Indiana • Iowa City, Iowa • Ann Arbor, Michigan + 1 more

Conditions: Mental Health, Vitamin D
Interventions: Placebo, Low dose Omega 3, High dose Omega 3; Dietary Supplement
Lead sponsor: University of Colorado, Colorado Springs; Other
Eligibility: 18 Years to 27 Years
Enrollment: 103 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Colorado Springs, Colorado

Conditions: Vitamin D Deficiency
Interventions: cholecalciferol; Dietary Supplement
Lead sponsor: Tufts University; Other
Eligibility: 50 Years and older
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Breast Neoplasms, Bone and Bones
Interventions: Calcitriol, Exercise, Multivitamin; Drug · Behavioral · Dietary Supplement
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older · Female only
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2018
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Chronic Kidney Disease, Secondary Hyperparathyroidism
Interventions: Cinacalcet HCl, Standard of Care; Drug · Dietary Supplement
Lead sponsor: Amgen; Industry
Eligibility: 6 Years to 17 Years
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 26
States / cities: Los Angeles, California • Wilmington, Delaware • Atlanta, Georgia + 22 more

Conditions: SARS-CoV-2 Infection
Interventions: Vitamin D3; Dietary Supplement
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 1,475 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Healthy, no Evidence of Disease
Interventions: cholecalciferol, questionnaire administration, trivalent influenza vaccine; Dietary Supplement · Other · Biological
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years to 64 Years
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: COVID-19, Vitamin D Deficiency, Respiratory Viral Infection
Interventions: Daily Vitamin D3, Daily placebo, Bolus vitamin D3, Bolus placebo; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 50 Years and older
Enrollment: 95 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Vitamin D Deficiency
Interventions: Vitamin D; Dietary Supplement
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Not listed
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Cincinnati, Ohio

Search by objective public record fields.

Calcitriol, Mitoxantrone, and Prednisone in Treating Patients With Metastatic Prostate Cancer

The ENERGY 3 Study: Evaluation of Efficacy and Safety of INZ-701 in Children With ENPP1 Deficiency

Can Vitamin D3 Improve Cognitive Function in Individuals With Type 2 Diabetes? (THINK-D)

Vitamin D in Pediatric Asthma: a Randomized Controlled Open-label Pilot Trial

Vitamin D as a Therapeutic Adjunct in the Stimulant Treatment of ADHD

High Dose Vitamin D Plus Multivitamin in the Prevention of Cluster Headache

Vitamin D as a Modifier of Serum Hepcidin in Children With Chronic Kidney Disease

Treatment Study of Vitamin D Deficiency in Adolescents

DAYLIGHT: Vitamin D Therapy in Individuals at High Risk of Hypertension

Safety, Efficacy, and Feasibility of High-dose Cholecalciferol in Pediatric Patients With Cystic Fibrosis

Pilot Pharmacokinetic Study of Daily Versus Monthly High-Dose Cholecalciferol Supplementation

Repeated-dose Safety, Efficacy, Pharmacokinetic and Pharmacodynamic of CTAP101, Immediate-release Calcifediol, High-dose Cholecalciferol, and Paricalcitol Plus Low-dose Cholecalciferol in Patients With Secondary Hyperparathyroidism, Chronic Kidney Disease 3-4 and Vitamin D Insufficiency

High Dose Interval Vitamin D Supplementation in Patients With IBD Receiving Remicade

Vitamin D and Physical Activity on Bone Health

Impact of Monthly High Dose Oral Cholecalciferol on Serum 25 Hydroxy Vitamin D Levels in Bariatric Surgery Subjects

Trial of High Dose Vitamin D in Patient's With Crohn's Disease

Omega-3 Supplementation and Mental Health in College Students

A Pilot Study of the Effect of Dietary Fat Type and Amount on Vitamin D3 Absorption

Calcitriol, Physical Activity, and Bone Health in Cancer Survivors

Efficacy and Safety of Cinacalcet in Pediatric Patients With Secondary Hyperparathyroidism (SHPT) and Chronic Kidney Disease (CKD) on Dialysis

Low vs. Moderate to High Dose Vitamin D for Prevention of COVID-19

Cholecalciferol and Flu Vaccine in Treating Healthy Participants

Vitamin D Supplementation in the Prevention and Mitigation of COVID-19 Infection

High Dose Vitamin D Replacement in Patients Undergoing Hematopoietic Stem Cell Transplantation