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Showing 1–24 of 84 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Vitamin D3 400 IU Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Consumption of Post-harvest UV-B Treated Mushrooms on Vitamin D Status of Healthy Adults

NCT01443897
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
1,000 IU vitamin D2, placebo capsule, mushrooms, UVB-treated mushrooms, 400 IU vitamin D2, UVB-treated mushrooms, 1,000 IU vitamin D2
Dietary Supplement · Other
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
20 Years to 59 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2011 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effect of Vitamin D3 Supplementation on Insulin Resistance and Cardiovascular Risk Factors in Obese Adolescents

NCT00858247
View directory record Official record
Conditions
Obesity
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 18 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 19, 2014 · Synced Sep 28, 2026, 4:18 AM EDT
Withdrawn Phase 4 Interventional

Sustained Effect of Urticaria Remission With Relatively High Dose Vitamin D Supplementation After Omalizumab Discontinuation

NCT02742805
View directory record Official record
Conditions
Urticaria
Interventions
Vitamin D (4,000 IU/day), Vitamin D (400 IU/day), Omalizumab
Dietary Supplement · Drug
Lead sponsor
Selina Gierer, D.O.
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis and CVD Risk

NCT04431960
View directory record Official record
Conditions
Postmenopausal Osteoporosis, Gut Microbiota, Cardiovascular Diseases
Interventions
blackcurrant (BC) extract
Drug
Lead sponsor
University of Connecticut
Other
Eligibility
45 Years to 60 Years · Female only
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Sep 28, 2026, 4:18 AM EDT
Active, not recruiting Phase 2 Interventional

RANKL Inhibition and Mammographic Breast Density

NCT04067726
View directory record Official record
Conditions
Dense Breasts
Interventions
Denosumab, Placebo, Calcium, Vitamin D3, Core needle biopsy, Blood draw
Drug · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years and older · Female only
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Phase 3 Interventional Results available

A Study of Actonel for the Prevention of Bone Loss

NCT00452439
View directory record Official record
Conditions
Leukemia, Lymphoma
Interventions
Actonel (Risedronate), Calcium, Vitamin D
Drug · Dietary Supplement
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 27, 2020 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

DAYLIGHT: Vitamin D Therapy in Individuals at High Risk of Hypertension

NCT01240512
View directory record Official record
Conditions
Hypertension, Vitamin D Deficiency, Pre-Hypertension
Interventions
Cholecalciferol
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
534 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
3
States / cities
Hartford, Connecticut • Boston, Massachusetts • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 8, 2017 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Phase 2 Interventional Results available

Study of Vitamin D in Untreated Metastatic Colorectal Cancer

NCT01516216
View directory record Official record
Conditions
Metastatic Colorectal Cancer
Interventions
FOLFOX + bevacizumab, Vitamin D
Drug · Dietary Supplement
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
18
States / cities
Boise, Idaho • Fruitland, Idaho • Meridian, Idaho + 13 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Changes in Biomarkers Using Prostaglandin Inhibitors

NCT01769625
View directory record Official record
Conditions
Biomarker Change Linked to Breast Cancer
Interventions
placebo/celecoxib 400 mg and cholecalciferol 400 IU/cholecalciferol 2,000 IU
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2016
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Aug 8, 2017 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Not applicable Interventional Results available

Improving Vitamin D Status in Home-bound Elders

NCT01410084
View directory record Official record
Conditions
Vitamin D Deficiency, Accidental Falls
Interventions
Vitamin D3, Vitamin E
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 8, 2019 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Not applicable Interventional Results available

Impact of Vitamin D on Diabetic Kidney Disease in African Americans

NCT01214356
View directory record Official record
Conditions
Diabetic Kidney Disease
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Low vs. Moderate to High Dose Vitamin D for Prevention of COVID-19

NCT04868903
View directory record Official record
Conditions
SARS-CoV-2 Infection
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
1,475 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Vitamin D Dose and Genotype of the Binding Protein in Infants and Children

NCT01050387
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Vitamin D
Dietary Supplement
Lead sponsor
Yale University
Other
Eligibility
6 Months to 6 Years
Enrollment
193 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 4, 2014 · Synced Sep 28, 2026, 4:18 AM EDT
Terminated Not applicable Interventional Results available

Study of Adults With Low Growth Hormone Who Survived Childhood Cancer Where Treatment Caused Low Bone Density

NCT00145704
View directory record Official record
Conditions
Osteopenia
Interventions
bisphosphonate therapy (risedronate), Vitamin D supplement, Calcium
Drug · Dietary Supplement
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2013 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Preventing Health Disparities During Pregnancy Through Vitamin D Supplementation

NCT01932788
View directory record Official record
Conditions
Vitamin D3 Deficiency
Interventions
Vitamin D3 4000 IU in gummy form, Placebo gummy vitamin
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
342 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Vitamin D Supplementation During Pregnancy on Clinical Outcomes and Immune Function

NCT01417351
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
400 IU vitamin D3, 2,000 IU Vitamin D3
Dietary Supplement
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
18 Years to 45 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
2
States / cities
Davis, California • Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2013 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Phase 2 Interventional

Calcium and Vitamin D vs Markers of Adenomatous Polyps

NCT00208793
View directory record Official record
Conditions
Colorectal Adenomatous Polyps
Interventions
Calcium and vitamin D3 combined, Placebo, Calcium, Vitamin D3
Dietary Supplement · Drug
Lead sponsor
Emory University
Other
Eligibility
30 Years to 74 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 25, 2013 · Synced Sep 28, 2026, 4:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effect Of Vitamin D On Measures Of Bone Health And Gene Expression

NCT01696409
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
400 IU vitamin D3, 2000 IU vitamin D3
Dietary Supplement
Lead sponsor
Boston University
Other
Eligibility
18 Years to 70 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Not applicable Interventional

Identifying Vitamin D Deficiency in Very Low Birth Weight Infant (VLBW) Infants Part 2

NCT01363167
View directory record Official record
Conditions
Infant, Very Low Birth Weight, Calcium Deficiency, Vitamin D Deficiency
Interventions
400 IU Cholecalciferol- Vitamin D Daily
Dietary Supplement
Lead sponsor
Medical University of South Carolina
Other
Eligibility
1 Day to 3 Days
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 23, 2014 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Vitamin D Status on Bones in Breastfed Infants

NCT00697294
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Tri-Vi-Sol
Dietary Supplement
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 2 Hours
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
3
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 4, 2011 · Synced Sep 28, 2026, 4:18 AM EDT
Terminated Not applicable Interventional Results available

Vitamin D Deficiency and Atopic Dermatitis

NCT01337635
View directory record Official record
Conditions
Atopic Dermatitis, Vitamin D Deficiency
Interventions
Vitamin D
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
1 Year to 18 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 4, 2018 · Synced Sep 28, 2026, 4:18 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application

NCT02758990
View directory record Official record
Conditions
Obesity, Rhinitis, Rhinitis, Allergic, Respiratory Sounds, Dyspnea, Headache, Migraine Disorders, Arthritis, Arthralgia, Anxiety, Sleep Initiation and Maintenance Disorders, Sleep Deprivation
Interventions
Vitamin A, Vitamin B6, Vitamin C, Nicotinamide, Vitamin D3, Vitamin E, Broccoli, Spinach, Caffeine, Coffee, Axon Eyewear, Chocolate
Dietary Supplement · Other · Device
Lead sponsor
Verifomics LLC
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2017 · Synced Sep 28, 2026, 4:18 AM EDT
Terminated Phase 4 Interventional Results available

Mothers' Own Milk Optimization for Preterm Infants Project (MoMO PIP) Pilot Study

NCT04629534
View directory record Official record
Conditions
Vitamin D Deficiency, Nutritional Deficiency
Interventions
High dose Cholecalciferol, Cholecalciferol
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
0 Days to 45 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 14, 2023 · Synced Sep 28, 2026, 4:18 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Aromatase Inhibition Versus Testosterone in Older Men With Low Testosterone: Randomized-Controlled Trial.

NCT00104572
View directory record Official record
Conditions
Hypogonadism, Diabetes, Sarcopenia, Osteoporosis, Depression
Interventions
Androgel (Testosterone Gel), Anastrozole (Aromatase Inhibitor), Placebo tablet, Placebo gel, Calcium Cardone 500mg with vitamin D 400 IU
Drug · Dietary Supplement
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
65 Years and older · Male only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 5, 2018 · Synced Sep 28, 2026, 4:18 AM EDT