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Showing 1–24 of 59 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 1 Interventional Results available

Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Advanced Malignancies and Hepatic Impairment

NCT01949545
View directory record Official record
Conditions
Solid Tumors, Hematologic Malignancies, Hepatic Impairment
Interventions
Carfilzomib
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
5
States / cities
Detroit, Michigan • Durham, North Carolina • Canton, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated May 1, 2017 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Phase 1Phase 2 Interventional

Phase I/II Dose Escalation Study of VELCADE® and Docetaxel in Patients With Advanced Androgen-Independent Prostate Cancer

NCT00064610
View directory record Official record
Conditions
Prostatic Neoplasms
Interventions
VELCADE TM (bortezomib) for Injection
Drug
Lead sponsor
Millennium Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older · Male only
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
4
States / cities
Los Angeles, California • New York, New York • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2008 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Not applicable Interventional

Virtual Weight Control Program Tailored for Adults With Type 2 Diabetes (VITAL)

NCT04804774
View directory record Official record
Conditions
Type2 Diabetes, Overweight and Obesity
Interventions
WW program modified for people with Type 2 diabetes
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 70 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
3
States / cities
Gainesville, Florida • Baton Rouge, Louisiana • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 20, 2022 · Synced Sep 1, 2026, 10:41 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Avoid and Resist Strategies for Weight Management

NCT05143931
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Home food environment and grocery delivery (AVOID), Inhibitory control training (RESIST), WW
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
14 Years and older
Enrollment
503 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Phase 3 Interventional Results available

Once-weekly Versus Twice-weekly Carfilzomib in Combination With Dexamethasone in Adults With Relapsed and Refractory Multiple Myeloma

NCT02412878
View directory record Official record
Conditions
Multiple Myeloma
Interventions
Carfilzomib, Dexamethasone
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years and older
Enrollment
478 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
12
States / cities
Scottsdale, Arizona • Bethesda, Maryland • Rockville, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2022 · Synced Sep 1, 2026, 10:41 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Perceptual Influences From Smoking Cannabis: an Experimental Study

NCT06588582
View directory record Official record
Conditions
Cannabis Use, Stress
Interventions
Water Temperature Variation - WW, Water Temperature Variation - CW
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
21 Years to 65 Years
Enrollment
166 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Not applicable Interventional

WW Improving Nutrition Study: A Randomized Controlled Trial

NCT05648344
View directory record Official record
Conditions
Overweight and Obesity
Interventions
WW, Control
Behavioral
Lead sponsor
Georgia Southern University
Other
Eligibility
18 Years to 70 Years
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Savannah, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Wits Workout Wellness Program for Older Adults

NCT04928885
View directory record Official record
Conditions
Cognitive Decline, Social Isolation, Health Behaviors, Self Efficacy
Interventions
Wits Workout Program, Control Group that receives intervention after the study
Behavioral · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years and older
Enrollment
285 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Not applicable Interventional

Evaluating the Feasibility, Health and Behavioral Impact of Mid-Ohio Farmacy + WW

NCT05536518
View directory record Official record
Conditions
Food Insecurity, Overweight and Obesity, Produce Prescription, Weight Change, Body
Interventions
Mid-Ohio Farmacy (produce prescription) + WW International Coaching (In person and/or Virtual)
Behavioral
Lead sponsor
Mid-Ohio Food Collective
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Grove City, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 17, 2023 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effectiveness of Naltrexone and/or Ondansetron to Reduce Craving for Alcohol and Drinking

NCT00183222
View directory record Official record
Conditions
Alcohol Dependence
Interventions
naltrexone (up to 50 mg/day) for 8 days; ondansetron (0.25 mg twice a day) for 8 days
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 65 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 4, 2010 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

PHASE 1 SARS-COV-2-Spike-Ferritin-Nanoparticle (SpFN) Vaccine With ALFQ Adjuvant for Prevention of COVID-19

NCT04784767
View directory record Official record
Conditions
SARS-CoV-2 Infection
Interventions
25 µg SpFN_1B-06-PL + ALFQ (QS21 Adjuvant), Sodium chloride, USP, for injection (0.9% NaCl), 50 µg SpFN_1B-06-PL + ALFQ (QS21 Adjuvant)
Biological · Drug
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years to 55 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 16, 2025 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Not applicable Interventional

Integration of Neurofunctional Phenotyping Into Investigation of CBT4CBT for AUD

NCT06190236
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Use Disorder
Interventions
Stand-alone web-based cognitive behavioral therapy (CBT4CBT) for alcohol use disorder
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 7, 2025 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Evaluation of a Commercial Program on Weight Loss and Health Outcomes

NCT03928483
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Modified WW Food program
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 10, 2019 · Synced Sep 1, 2026, 10:41 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

"Immunomodulation in GWI (Phlebotomy)"

NCT04058275
View directory record Official record
Conditions
Gulf War Illness
Interventions
Draw blood (phlebotomy, 83 ml)
Other
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Phase 1 Interventional Results available

Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

NCT02303821
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia (ALL)
Interventions
Carfilzomib, Dexamethasone, Mitoxantrone, PEG-asparaginase, Vincristine, Intrathecal (IT) Methotrexate, Intrathecal Triple Therapy (Intrathecal Cytarabine, Hydrocortisone, and Methotrexate), 6-Mercaptopurine, Cyclophosphamide, Cytarabine, Daunorubicin
Drug
Lead sponsor
Amgen
Industry
Eligibility
1 Month to 21 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
22
States / cities
Oakland, California • Orange, California • Aurora, Colorado + 19 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Not applicable Interventional

Preventing Diabetes

NCT05395377
View directory record Official record
Conditions
PreDiabetes
Interventions
Registered Dietitian/Nutritionist, Diabetes Prevention Program, Weight Watchers, Reimagined, DPP or RDN Counseling + Medication, Bariatric Surgery Evaluation
Behavioral · Other
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 26, 2022 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Phase 2 Interventional

Phase 2 Study of VELCADE Alone or VELCADE® Plus Docetaxel in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer

NCT00051974
View directory record Official record
Conditions
Non-Small Cell Lung Cancer
Interventions
VELCADE™ (bortezomib) for Injection (formerly PS-341)
Drug
Lead sponsor
Millennium Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
20
States / cities
Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 15 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2008 · Synced Sep 1, 2026, 10:41 AM EDT
Completed No phase listed Observational Results available

Testing the Effectiveness of WW Clinic GLP1

NCT06034457
View directory record Official record
Conditions
Weight Loss, Obesity
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Phase 1 Interventional

Intraoperative Imaging of Thoracic Malignancies With Indocyanine Green

NCT01335893
View directory record Official record
Conditions
Lung Neoplasms
Interventions
Indocyanine Green
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2018 · Synced Sep 1, 2026, 10:41 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Racial Differences in Vagal Control of Glucose Homeostasis, Chronic Study

NCT03014323
View directory record Official record
Conditions
Insulin Sensitivity, Oxidative Stress
Interventions
Galantamine, Placebo
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 60 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 12, 2018 · Synced Sep 1, 2026, 10:41 AM EDT
Terminated Phase 4 Interventional Results available

Evaluate the Efficacy and Safety Growth Hormone, Glutamine and Diet in Patients With Short Bowel Syndrome (SBS)

NCT00742157
View directory record Official record
Conditions
Short Bowel Syndrome
Interventions
Growth Hormone
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 78 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 7, 2023 · Synced Sep 1, 2026, 10:41 AM EDT
Completed Phase 2 Interventional Results available

Phase 2 Study of Carfilzomib in Relapsed Multiple Myeloma

NCT00530816
View directory record Official record
Conditions
Multiple Myeloma
Interventions
carfilzomib
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
26
States / cities
Scottsdale, Arizona • Beverly Hills, California • Laguna Hills, California + 23 more
Source: ClinicalTrials.gov public record
Updated May 1, 2017 · Synced Sep 1, 2026, 10:41 AM EDT
Terminated Phase 3 Interventional

Study Evaluating CCI-779 and Letrozole in Post-menopausal Women With Breast Cancer

NCT00083993
View directory record Official record
Conditions
Breast Neoplasms, Neoplasm Metastasis
Interventions
Temsirolimus (CCI-779) for 34 months, Letrozole for 34 months
Drug
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
112
States / cities
Hoover, Alabama • Huntsville, Alabama • Tucson, Arizona + 98 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2011 · Synced Sep 1, 2026, 10:41 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Study of Thyroid Hormones in Prematures

NCT02103998
View directory record Official record
Conditions
Transient Hypothyroxinemia of Prematurity (THOP)
Interventions
thryoid hormone T4 + oral potassium iodide (KI) for 42 days, D5W - 5% dextrose water
Drug
Lead sponsor
New York Medical College
Other
Eligibility
1 Hour to 24 Hours
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Apr 23, 2019 · Synced Sep 1, 2026, 10:41 AM EDT