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ClinicalTrials.gov public records Last synced Oct 19, 2026, 8:14 PM EDT

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Showing 145–168 of 740 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Wake Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Online Insomnia Intervention to Reduce Alcohol Use

NCT05630118
View directory record Official record
Conditions
Alcohol Use Disorder, Heavy Drinking
Interventions
SHUTi Intervention, Web-Based Insomnia Education Program
Behavioral
Lead sponsor
Jessica Weafer
Other
Eligibility
18 Years to 50 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Circadian Rhythms and Sleep-Wake Cycles in Parkinson's Disease

NCT01742182
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Light exposure
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
55 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional Results available

Wake Therapy in the Treatment of Depression

NCT01431573
View directory record Official record
Conditions
Major Depressive Disorder, Bipolar Disorder
Interventions
Wake Therapy, light box, Lithium
Behavioral · Device · Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 18, 2021 · Synced Oct 19, 2026, 8:14 PM EDT
Completed No phase listed Observational

Attitudes and Knowledge Regarding Clinical Trials in Underserved Populations Receiving Care at the Comprehensive Cancer Center of Wake Forest University

NCT02444754
View directory record Official record
Conditions
Malignant Neoplasm
Interventions
Medical Chart Review, Questionnaire Administration, Survey Administration
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 8, 2023 · Synced Oct 19, 2026, 8:14 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Social Determinants and Smoking Cessation

NCT01310842
View directory record Official record
Conditions
Smoking Cessation
Interventions
Questionnaires, Nicotine Patch Therapy, Counseling Sessions
Behavioral · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years to 65 Years
Enrollment
329 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2016 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Phase 2 Interventional

RECOVER-SLEEP: Platform Protocol

NCT06404086
View directory record Official record
Conditions
Long COVID, Long COVID-19, Hypersomnia, Sleep Disturbance
Interventions
Modafinil, Modafinil Placebo, Solriamfetol, Solriamfetol Placebo, Melatonin, Melantonin Placebo, Tailored lighting (TL) Active, Tailored lighting (TL) Placebo
Drug · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
830 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
47
States / cities
Phoenix, Arizona • Tucson, Arizona • Palo Alto, California + 31 more
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Not yet recruiting Not applicable Interventional

Wide-Awake Local Anesthesia No-Tourniquet (WALANT) Procedures

NCT07832591
View directory record Official record
Conditions
Hand Injuries and Disorders
Interventions
Preoperative WALANT Educational Video, Traditional Preoperative Counseling
Behavioral
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional Results available

Application of a Reimbursable Form of Constraint-Induced Movement Therapy for Upper Extremity

NCT05311384
View directory record Official record
Conditions
CVA (Cerebrovascular Accident), Stroke, Upper Extremity Paresis
Interventions
Keys Constraint-induced Movement Therapy protocol
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 7, 2025 · Synced Oct 19, 2026, 8:14 PM EDT
Active, not recruiting Not applicable Interventional

Brain, Emotions, and Mind-Wandering

NCT05345392
View directory record Official record
Conditions
Mood Disorders
Interventions
Mindfulness-Based Intervention (MBI), Health and Wellness Intervention (HWI)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
11 Years to 14 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional Results available

Belun Ring Platform With an Improved Algorithm for OSA Assessment

NCT04885062
View directory record Official record
Conditions
Sleep-Disordered Breathing, Sleep Architecture
Interventions
Belun Ring, PSG
Device · Diagnostic Test
Lead sponsor
Belun Technology Company Limited
Other
Eligibility
18 Years to 80 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impact of Sleep Restriction on Performance in Adults

NCT02960776
View directory record Official record
Conditions
Sleep, Obesity, Sleep Restriction
Interventions
Sleep Restriction (SR)
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
20 Years to 75 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 19, 2026, 8:14 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Wake and Sleep State Transitions on a Portable Electroencephalogram (EEG) Device in Narcolepsy Type 1 (NT1) and Healthy Participants

NCT04445129
View directory record Official record
Conditions
Healthy Volunteers, Narcolepsy Type 1
Interventions
Portable EEG Device, Portable ECG Device, Accelerometry
Device
Lead sponsor
Takeda
Industry
Eligibility
16 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
13
States / cities
Redwood City, California • Colorado Springs, Colorado • Clearwater, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated May 7, 2021 · Synced Oct 19, 2026, 8:14 PM EDT
Completed No phase listed Observational

Changes in Heart Rhythms Associated With Antipsychotic Drug Treatment

NCT00538122
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
Interventions
24 Holter Monitor Recording
Device
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 27, 2009 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional

Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings

NCT05030272
View directory record Official record
Conditions
Tobacco Use Disorder, Mental Illness, Recurring Major Depressive Disorder, Bipolar Disorder, Schizophrenia, Schizoaffective Disorder, Persistent Depressive Disorder
Interventions
Quit on the Go App (formerly "Learn to Quit " App), Brief advice, Nicotine patch, Smartphone coaching, Nicotine gum, Nicotine Lozenges
Device · Behavioral · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Buffalo, New York • Durham, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional

Adjunctive Bright Light Therapy for Opioid Use Disorder

NCT05459922
View directory record Official record
Conditions
Opioid Use Disorder, Sleep Disturbance
Interventions
Wearable bright light therapy device, Wearable placebo light therapy device
Device
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional Results available

Cranial Electrotherapy Stimulation for the Treatment of Major Depressive Disorder in Adults

NCT05384041
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Fisher Wallace Cranial Electrotherapy Stimulator (Active Device), Fisher Wallace Cranial Electrotherapy Stimulator (Placebo Device)
Device
Lead sponsor
Fisher Wallace Laboratories
Industry
Eligibility
21 Years to 65 Years
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 19, 2026, 8:14 PM EDT
Not yet recruiting Phase 1 Interventional

Improving Sleep in a Psychiatric Hospital

NCT07010718
View directory record Official record
Conditions
Sleep Disorder, Mental Health Issue
Interventions
Scented Oil, Ear Plugs, Eye Mask, Video based safety check, In person safety check
Drug · Device · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 8, 2025 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Phase 2 Interventional Results available

Memory Improvement Through Nicotine Dosing (MIND) Study

NCT02720445
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Nicotine Transdermal Patch, Placebo Patch
Drug
Lead sponsor
University of Southern California
Other
Eligibility
55 Years to 90 Years
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
36
States / cities
Scottsdale, Arizona • North Little Rock, Arkansas • Downey, California + 31 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Phase 2 Interventional

Study to Determine the Effects Treatment With Amlexanox 0.5% Oral Rinse Solution on Oral Mucositis Associated With Radiation Therapy for Cancer of the Head and Neck Region

NCT01083875
View directory record Official record
Conditions
Oral Mucositis
Interventions
amlexanox, Vehicle rinse
Drug
Lead sponsor
Access Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2001
U.S. locations
12
States / cities
Mobile, Alabama • Little Rock, Arkansas • Bakersfield, California + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 18, 2010 · Synced Oct 19, 2026, 8:14 PM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study

NCT07360301
View directory record Official record
Conditions
Well-Being, Psychological, Psychedelic Experiences
Interventions
Psilocybin, Saline Placebo, Clonidine
Drug · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 45 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Terminated Phase 2 Interventional Results available

Home-Based Programs for Improving Sleep in Cancer Survivors

NCT00993928
View directory record Official record
Conditions
Cancer Survivor, Fatigue, Psychosocial Effects of Cancer and Its Treatment, Sleep Disorders
Interventions
Home-based sleep intervention
Behavioral
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
193
States / cities
Scottsdale, Arizona • Hartford, Connecticut • Lakeland, Florida + 126 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2019 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Doctors for Coronavirus Prevention Project Thanksgiving / Christmas Messaging Campaign

NCT04644328
View directory record Official record
Conditions
Covid19
Interventions
Facebook Ads on the importance of staying safe during the Thanksgiving / Christmas holiday
Behavioral
Lead sponsor
National Bureau of Economic Research, Inc.
Other
Eligibility
18 Years and older
Enrollment
820 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 21, 2021 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vitamin C to Reduce Morning Cardiovascular Risk

NCT03290612
View directory record Official record
Conditions
Cardiovascular Risk Factor
Interventions
Vitamin C, Placebo
Dietary Supplement · Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
40 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Oct 19, 2026, 8:14 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effect of Hatha Yoga on Mental Health

NCT05777044
View directory record Official record
Conditions
Depression, Anxiety, Mental Health Issue
Interventions
Yoga
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
18 Years to 35 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 20, 2023 · Synced Oct 19, 2026, 8:14 PM EDT