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Showing 1–24 of 59 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Walnut Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Walnut Consumption and Gut Microbiota

NCT05441748
View directory record Official record
Conditions
Obesity, Inflammation
Interventions
Walnuts, Walnut Oil, Control
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
25 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 17, 2023 · Synced Sep 5, 2026, 4:27 PM EDT
Withdrawn Not applicable Interventional

Walnut Oral Immunotherapy for Tree Nut Allergy

NCT01918657
View directory record Official record
Conditions
Peanut Allergy
Interventions
walnut powder
Drug
Lead sponsor
Jonathan Spergel
Other
Eligibility
6 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2014 · Synced Sep 5, 2026, 4:27 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Infancy to Toddlerhood: Early Nutrition & Tolerance (INTENT)

NCT04803981
View directory record Official record
Conditions
Diet Diversity, Infant Nutrition
Interventions
SpoonfulONE
Other
Lead sponsor
Before Brands, Inc
Industry
Eligibility
4 Months to 6 Months
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Activation of Brain Centers by Short-term Walnut Consumption in Obesity

NCT02673281
View directory record Official record
Conditions
Obesity
Interventions
Walnut shake, Placebo shake
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Not applicable Interventional

Effects of Walnut Consumption on Endothelial Function in Type 2 Diabetes

NCT00901043
View directory record Official record
Conditions
DIABETES MELLITUS TYPE 2
Interventions
Walnut supplementation, Ad lib diet
Dietary Supplement
Lead sponsor
Griffin Hospital
Other
Eligibility
35 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Not applicable Interventional

Effects of Walnuts on Endothelial Function in Overweight Adults With at Least One Factor of Metabolic Syndrome

NCT01413646
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Walnut Supplementation, No walnut supplementation
Dietary Supplement
Lead sponsor
Griffin Hospital
Other
Eligibility
25 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Not applicable Interventional

Effect of High-Dose Guarana And Cancer-Related Fatigue

NCT03897556
View directory record Official record
Conditions
Cancer-related Fatigue
Interventions
Guarana herb, Usual Care
Dietary Supplement · Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Walnut and Immunity Study

NCT05915390
View directory record Official record
Conditions
Immune Response, Upper Respiratory Tract Infection
Interventions
walnuts, Habitual diet
Dietary Supplement
Lead sponsor
Loma Linda University
Other
Eligibility
55 Years to 75 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Not applicable Interventional Results available

Nuts and Oil Pilot Study

NCT04361617
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Daily consumption of tree nuts and extra virgin olive oil
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
35 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 17, 2023 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Influence of Walnut Intake on Vascular Function and Metabolism

NCT03900403
View directory record Official record
Conditions
Overweight and Obesity, Endothelial Dysfunction, Cardiovascular Risk Factor
Interventions
Walnut Intake
Other
Lead sponsor
University of California, Davis
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Sep 5, 2026, 4:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mechanistic Effect of Walnut Consumption on Sleep Quality

NCT06430086
View directory record Official record
Conditions
Poor Sleep Quality
Interventions
Walnut consumption, HCHS consumption
Other
Lead sponsor
Columbia University
Other
Eligibility
45 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 5, 2026, 4:27 PM EDT
Active, not recruiting Not applicable Interventional

Response of Cardiometabolic Biomarkers and Gut Microbiota to Walnut Consumption

NCT05321277
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Walnuts, No-nut diet
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
45 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nuts and Olestra for Persistent Organic Pollutant Reduction (NO-POPs) Trial

NCT02675101
View directory record Official record
Conditions
Persistent Organic Pollutants, Endocrine Disrupting Chemicals, Endocrine Disruptor Effects
Interventions
Whole Nuts, Olestra: Fat Free Pringles, Vegetable Oil: Original Pringles
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
45 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 4, 2019 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of California Walnuts on Vascular Function in Postmenopausal Women

NCT01072864
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Walnuts
Other
Lead sponsor
University of California, Davis
Other
Eligibility
50 Years to 70 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2010 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Not applicable Interventional

Snacking, Satiety &Weight: A Randomized, Controlled Trial

NCT02050165
View directory record Official record
Conditions
Obesity
Interventions
KIND Bars, Typical American Snack
Dietary Supplement
Lead sponsor
Griffin Hospital
Other
Eligibility
25 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Mastication on Energy Release From Walnuts

NCT02927028
View directory record Official record
Conditions
Obesity
Interventions
Chewing
Other
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Sep 5, 2026, 4:27 PM EDT
Not listed Not applicable Interventional

Metabolomics Initiative: Mediterranean-amplified vs Habitual Western Diet on Food Signatures, Health, and Microbiome

NCT05500976
View directory record Official record
Conditions
Dietary Habits
Interventions
Semi-controlled dietary intervention - Western, Semi-controlled dietary intervention - MiniMed
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 69 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Sep 5, 2026, 4:27 PM EDT
Terminated Not applicable Interventional

Walnuts and Glucose Variability

NCT01787214
View directory record Official record
Conditions
Type-2 Diabetes
Interventions
Full dose, Half dose, Control
Dietary Supplement
Lead sponsor
Loma Linda University
Other
Eligibility
40 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2014 · Synced Sep 5, 2026, 4:27 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Walnuts on Cognitive Function and Gut Microbiome in Older Adults

NCT06942351
View directory record Official record
Conditions
Aging, Inflammation Biomarkers
Interventions
Walnuts, Crackers
Other
Lead sponsor
Oregon State University
Other
Eligibility
55 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Corvallis, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 5, 2026, 4:27 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Response of Gut Microbiota and Cardiometabolic Biomarkers to Consumption of Walnuts

NCT04307628
View directory record Official record
Conditions
Healthy, Normal Weight, Overweight, Obese
Interventions
Walnut, Nut-Free
Other
Lead sponsor
University of California, Davis
Other
Eligibility
20 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Not applicable Interventional

A Mediterranean Diet Nutrition Education Program for the Reduction of Cardiovascular Disease Risk in the Southeastern U.S.

NCT03683134
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiovascular Risk Factor, Obesity
Interventions
Mediterranean diet, Olive oil and mixed nuts, American Heart Association
Behavioral · Dietary Supplement
Lead sponsor
Auburn University
Other
Eligibility
19 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 26, 2018 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Phase 1Phase 2 Interventional Results available

ADP101 for Oral Immunotherapy in Food-Allergic Children and Adults

NCT04856865
View directory record Official record
Conditions
Food Allergy
Interventions
Low dose ADP101, High dose ADP101, Pooled Placebo
Biological
Lead sponsor
Alladapt Immunotherapeutics, Inc.
Industry
Eligibility
4 Years to 55 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
15
States / cities
Mission Viejo, California • Rolling Hills Estates, California • San Diego, California + 12 more
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Sep 5, 2026, 4:27 PM EDT
Recruiting Not applicable Interventional

Walnuts as an Infant Solid Food for Health

NCT07081698
View directory record Official record
Conditions
Gut -Microbiota, Inflammatory Markers, Infant Development
Interventions
Infant walnut intake
Other
Lead sponsor
Colorado State University
Other
Eligibility
5 Months to 5 Months
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Sep 5, 2026, 4:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Walnuts on Central Blood Pressure, Arterial Stiffness Indices, Lipoproteins, and Other CVD Risk Factors

NCT02210767
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Walnut Diet, Walnut Control Diet, Low ALA Diet
Other
Lead sponsor
Penn State University
Other
Eligibility
30 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 5, 2026, 4:27 PM EDT