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ClinicalTrials.gov public records Last synced Oct 18, 2026, 2:10 AM EDT

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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Walnut consumption Clear all
Recruiting Not applicable Interventional

Essential Fats For Enhancing Cognitive Thinking (EFFECT) Study

NCT06223672
View directory record Official record
Conditions
Cognitive Decline, Cognitive Impairment
Interventions
Walnuts, Simply White Diary-free chocolate bar
Other
Lead sponsor
Ohio State University
Other
Eligibility
40 Years to 75 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ellagic Acid, Urolithin and Colonic Microbial Communities Affected by Walnut Consumption

NCT04066816
View directory record Official record
Conditions
Colo-rectal Cancer, Colon Cancer, Diet Habit
Interventions
Walnuts
Other
Lead sponsor
UConn Health
Other
Eligibility
50 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 26, 2021 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Metabolic Effects of Short-term Walnut Consumption in Subjects With the Metabolic Syndrome

NCT00525629
View directory record Official record
Conditions
Metabolic Syndrome, Type 2 Diabetes, Cardiovascular Disease
Interventions
Walnuts, Control
Dietary Supplement
Lead sponsor
Christos Mantzoros
Other
Eligibility
40 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 15, 2017 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional

A Mediterranean Diet Nutrition Education Program for the Reduction of Cardiovascular Disease Risk in the Southeastern U.S.

NCT03683134
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiovascular Risk Factor, Obesity
Interventions
Mediterranean diet, Olive oil and mixed nuts, American Heart Association
Behavioral · Dietary Supplement
Lead sponsor
Auburn University
Other
Eligibility
19 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Oct 18, 2026, 2:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Walnut Consumption and Diabetes Risk

NCT03224533
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Diabetes Outcome
Diagnostic Test
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 80 Years
Enrollment
34,121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Oct 18, 2026, 2:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mechanistic Effect of Walnut Consumption on Sleep Quality

NCT06430086
View directory record Official record
Conditions
Poor Sleep Quality
Interventions
Walnut consumption, HCHS consumption
Other
Lead sponsor
Columbia University
Other
Eligibility
45 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of California Walnuts on Vascular Function in Postmenopausal Women

NCT01072864
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Walnuts
Other
Lead sponsor
University of California, Davis
Other
Eligibility
50 Years to 70 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2010 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Walnuts and Colon Health (The WellNut Trial)

NCT05195970
View directory record Official record
Conditions
Colorectal Cancer, Diet Habit
Interventions
Walnuts
Other
Lead sponsor
UConn Health
Other
Eligibility
39 Years to 75 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Farmington, Connecticut • New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional

Effect of Daily Walnut Consumption on Memory in Subjects With Long-COVID

NCT07429903
View directory record Official record
Conditions
Long-COVID, Brain Fog, Cognition, Memory
Interventions
whole food - walnuts
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
40 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 18, 2026, 2:10 AM EDT
Active, not recruiting Not applicable Interventional

Response of Cardiometabolic Biomarkers and Gut Microbiota to Walnut Consumption

NCT05321277
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Walnuts, No-nut diet
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
45 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 18, 2026, 2:10 AM EDT
Recruiting Not applicable Interventional

A Nutrition & Exercise Prehabilitation Intervention on Inflammatory Biomarkers in AI Cancer Patients

NCT06644560
View directory record Official record
Conditions
Cancer
Interventions
Prehabilitation Intervention
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Activation of Brain Centers by Short-term Walnut Consumption in Obesity

NCT02673281
View directory record Official record
Conditions
Obesity
Interventions
Walnut shake, Placebo shake
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nuts and Olestra for Persistent Organic Pollutant Reduction (NO-POPs) Trial

NCT02675101
View directory record Official record
Conditions
Persistent Organic Pollutants, Endocrine Disrupting Chemicals, Endocrine Disruptor Effects
Interventions
Whole Nuts, Olestra: Fat Free Pringles, Vegetable Oil: Original Pringles
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
45 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional

Walnut Consumption, Endothelial Function, and Biomarkers

NCT01884363
View directory record Official record
Conditions
Coronary Heart Disease, Type 2 Diabetes
Interventions
Once ounce per day of walnuts
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
30 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2016 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional

Snacking, Satiety &Weight: A Randomized, Controlled Trial

NCT02050165
View directory record Official record
Conditions
Obesity
Interventions
KIND Bars, Typical American Snack
Dietary Supplement
Lead sponsor
Griffin Hospital
Other
Eligibility
25 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Oct 18, 2026, 2:10 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Response of Gut Microbiota and Cardiometabolic Biomarkers to Consumption of Walnuts

NCT04307628
View directory record Official record
Conditions
Healthy, Normal Weight, Overweight, Obese
Interventions
Walnut, Nut-Free
Other
Lead sponsor
University of California, Davis
Other
Eligibility
20 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Lean Living Study

NCT02501889
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Walnut-rich weight loss diet, Standard weight loss diet
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional

Effects of Walnut Consumption on Endothelial Function in Type 2 Diabetes

NCT00901043
View directory record Official record
Conditions
DIABETES MELLITUS TYPE 2
Interventions
Walnut supplementation, Ad lib diet
Dietary Supplement
Lead sponsor
Griffin Hospital
Other
Eligibility
35 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Walnuts on Antioxidant Capacity and Nutritional Status in Humans

NCT00626691
View directory record Official record
Conditions
Healthy
Interventions
Walnut consumption
Behavioral
Lead sponsor
Tufts University
Other
Eligibility
50 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 19, 2009 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Black Walnuts and Health

NCT04849949
View directory record Official record
Conditions
Healthy
Interventions
Control, Black walnut, English walnut
Other
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 45 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 20, 2021 · Synced Oct 18, 2026, 2:10 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Walnut Consumption and Gut Microbiota

NCT05441748
View directory record Official record
Conditions
Obesity, Inflammation
Interventions
Walnuts, Walnut Oil, Control
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
25 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Phase 3 Interventional Results available

Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic Participants

NCT03881696
View directory record Official record
Conditions
Peanut Allergy, Multi-food Allergy
Interventions
Omalizumab, Placebo for Omalizumab, Multi-Allergen Oral Immunotherapy, Placebo for Multi-Allergen Oral Immunotherapy, Double-Blind Placebo-Controlled Food Challenge Based Treatment
Drug · Other
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
1 Year to 55 Years
Enrollment
458 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
10
States / cities
Little Rock, Arkansas • Stanford, California • Denver, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Pomegranate Juice Consumption on the Health of Mothers and Infants During Breastfeeding

NCT04341961
View directory record Official record
Conditions
Breastfeeding
Interventions
Pomegranate Juice
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2020 · Synced Oct 18, 2026, 2:10 AM EDT
Completed Not applicable Interventional Results available

Nuts and Oil Pilot Study

NCT04361617
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Daily consumption of tree nuts and extra virgin olive oil
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
35 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 18, 2023 · Synced Oct 18, 2026, 2:10 AM EDT