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Showing 745–768 of 1,152 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers Results available

In-Home Technology for Dementia Caregivers

NCT03828383
Conditions
Dementia, Alzheimer's Disease, Frontotemporal Dementia
Interventions
In-home technology, Limited in-home technology
Device
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
5
States / cities
Berkeley, California • Los Angeles, California • Orange, California + 2 more
Completed Phase 4 Interventional Accepts healthy volunteers

A Twelve Week Study of Supervised Mouth Rinse and Flossing

NCT04696536
Conditions
Healthy
Interventions
Colgate Cavity Protection Toothpaste, American Dental Association (ADA) Referenced Toothbrush, 5% Hydroalcohol Mouth Rinse, REACH Dental Floss, Alcohol-containing Essential Oil (AEO) Mouth Rinse (Listerine Cool Mint, marketed)
Other
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Fort Wayne, Indiana
Conditions
Neurofibromatoses
Interventions
Part 1 Levulan injection, Part 1 Levulan surface application, Part 1 Levulan surface application twice, Part 1 Levulan surface application twice with microneedling, Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 1, Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 2, Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 3
Drug
Lead sponsor
Harry T Whelan, MD
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Acute Mountain Sickness (AMS)
Interventions
T89 capsule, Placebo capsule
Drug
Lead sponsor
Tasly Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
853 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Francisco, California
Conditions
Obesity and Overweight
Interventions
Postbiotic, Placebo
Dietary Supplement
Lead sponsor
ResBiotic Nutrition, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

Effect of RECK in Posterior Spinal Fusion

NCT06447194
Conditions
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
Interventions
Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail, Placebo
Drug · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Advanced Cancers
Interventions
Surface-Controlled Water Soluble Curcumin, Surface-Controlled Water Soluble Curcumin MTD
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
13 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Houston, Texas
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Safety and Immunogenicity of PanBlok Influenza Vaccine in Healthy Adults

NCT01147068
Conditions
Influenza
Interventions
0.5mL Intramuscular Injection
Biological
Lead sponsor
Protein Sciences Corporation
Industry
Eligibility
18 Years to 49 Years
Enrollment
392 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
4
States / cities
Overland Park, Kansas • Omaha, Nebraska • Rochester, New York + 1 more
Conditions
Xerosis Cutis
Interventions
IDL lotion, Control lotion
Combination Product
Lead sponsor
Shyla Cantor
Industry
Eligibility
35 Years to 57 Years · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Blauvelt, New York
Conditions
Acute Pain, Burns, Adverse Drug Event, Respiratory Depression, Nausea and Vomiting, Postoperative
Interventions
Oliceridine, Historical opioid use
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Memphis, Tennessee
Recruiting Not applicable Interventional

Family Spirit Strengths

NCT05836090
Conditions
Depressive Symptoms, Anxiety Disorders and Symptoms, Substance Use, Mental Health Issue
Interventions
Family Spirit Strengths (FSS), Family Spirit Nurture
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
14 Years and older · Female only
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Chinle, Arizona • Pokagon, Michigan • Shiprock, New Mexico
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers

Can Simple and Inexpensive Techniques Enhance Patient Comfort

NCT00747084
Conditions
Colonoscopy
Interventions
Colonoscopy
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Sepulveda, California
Conditions
Sepsis, Neonatal Mortality, Antibiotic Resistant Infection, Enteric Infections, Serious Bacterial Infection
Interventions
chlorination for water disinfection and surface disinfection, infection prevention and control messaging
Device · Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
Not listed
Enrollment
45,450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Berkeley, California
Not yet recruiting Not applicable Interventional

Trial of NASHA Dx Urethral Bulking System

NCT07850804
Conditions
Urinary Incontinence, Urinary Incontinence (UI), Urinary Incontinence , Stress, Urinary Incontinence Due to Urethral Sphincter Incompetence, Urethral Sphincter Activity, Intrinsic Sphincter Deficiency, Pelvic Floor Dysfunction
Interventions
NASHA Dx, Bulkamid
Device
Lead sponsor
Palette Life Sciences, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
5
States / cities
Tustin, California • Lincoln, Nebraska • Charlotte, North Carolina + 2 more
Completed Not applicable Interventional Accepts healthy volunteers

Rural Appalachia Pilot Water Treatment Trial

NCT06120985
Conditions
Water-Related Diseases, Enteric Pathogens, Exposure to Chemical Pollution
Interventions
Countertop pitcher water filter
Device
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
6 Months and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Johnson City, Tennessee • Blacksburg, Virginia
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Water is K'é: Multi-level Intervention to Promote Healthy Beverage Choices Among Navajo Families

NCT06020027
Conditions
Water, Child Nutrition, Family Dynamics, Healthy Nutrition, Healthy Lifestyle, Health-Related Behavior, Obesity Prevention
Interventions
Water is K'é
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
2 Years and older
Enrollment
1,160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Window Rock, Arizona
Recruiting Not applicable Interventional Accepts healthy volunteers

Stress & Self-Control Costs

NCT05795179
Conditions
Self-Control
Interventions
Cold-Pressor Task (CPT), Trier Social Stress Test (TSST), Modified Non-Stress CPT, Modified Non-Stress TSST, Functional Magnetic Resonance Imaging (fMRI)
Behavioral · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Hepatic Impairment
Interventions
Lemborexant
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 79 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
2
States / cities
Miami, Florida • Orlando, Florida
Conditions
Pain
Interventions
TRV130, Morphine, Placebo
Drug
Lead sponsor
Trevena Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Pasadena, California • Houston, Texas
Conditions
Gulf War Syndrome
Interventions
Lactulose Breath Test, Rifaximin, Placebo
Procedure · Drug
Lead sponsor
Henry C. Lin, MD
Federal
Eligibility
21 Years and older
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
1
States / cities
Albuquerque, New Mexico
Conditions
Hypertension
Interventions
Potassium chloride powder, Potassium magnesium Citrate (KMgCit), Potassium citrate powder, Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Obesity and Overweight, Dysbiosis
Interventions
Watermelon, Belvita Breakfast Sandwich + 12 oz Water
Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 30 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tallahassee, Florida
Conditions
Limb-Girdle Muscular Dystrophy Type 2I (LGMD2I)
Interventions
BBP-418 (ribitol), Placebo
Drug · Other
Lead sponsor
ML Bio Solutions, Inc.
Industry
Eligibility
12 Years to 60 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
13
States / cities
Little Rock, Arkansas • Irvine, California • Aurora, Colorado + 9 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Pain in Juvenile Arthritis

NCT07217782
Conditions
Juvenile Idiopathic Arthritis
Interventions
Pressure pain thresholds (measured in kilopascal), Cold pain tolerance (duration in seconds)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
9 Years to 17 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2035
U.S. locations
1
States / cities
St Louis, Missouri