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Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Watermelon Clear all
Completed Phase 2Phase 3 Interventional

Cyrotherapy vs. APC in GAVE

NCT00587405
View directory record Official record
Conditions
Watermelon Stomach
Interventions
cryotherapy, Argon Plasma Coagulation
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 6, 2016 · Synced Sep 5, 2026, 10:39 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers

NCT06264154
View directory record Official record
Conditions
Smoking, Tobacco Use, Cigarette Smoking, E-Cig Use
Interventions
E-cigarettes
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
21 Years and older
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 5, 2026, 10:39 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers

NCT06372899
View directory record Official record
Conditions
E-cigarette Use, Cigarette Smoking, Harm Reduction, Tobacco Use
Interventions
E-cigarettes, Oral nicotine pouches
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
21 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 5, 2026, 10:39 PM EDT
Recruiting Not applicable Interventional

Effect of Watermelon on Gut and Cardiometabolic Health

NCT06588218
View directory record Official record
Conditions
Obesity and Overweight, Dysbiosis
Interventions
Watermelon, Belvita Breakfast Sandwich + 12 oz Water
Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 30 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 5, 2026, 10:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Childcare Outdoor Learning Environments as Active Food Systems

NCT04864574
View directory record Official record
Conditions
Pediatric Obesity, Sedentary Behavior
Interventions
Garden installation
Other
Lead sponsor
North Carolina State University
Other
Eligibility
42 Months to 6 Years
Enrollment
286 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
15
States / cities
Cary, North Carolina • Fuquay-Varina, North Carolina • Knightdale, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Sep 5, 2026, 10:39 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Watermelon or Low-fat Cookie Consumption on Wellness

NCT06323070
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Low-fat cookies, Watermelon
Other
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 50 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 5, 2026, 10:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Predictors and Consequences of Combustible Cigarette Smokers' Switch to Standardized Research E-Cigarettes

NCT03277495
View directory record Official record
Conditions
Tobacco Use
Interventions
Brief behavioral counseling
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
21 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 5, 2026, 10:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Watermelon Juice Supplementation on Postprandial Vascular Endothelial Function

NCT04092439
View directory record Official record
Conditions
Endothelial Dysfunction
Interventions
Watermelon Juice
Dietary Supplement
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 40 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Sep 5, 2026, 10:39 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes

NCT04038515
View directory record Official record
Conditions
Nicotine, E-liquid Flavors
Interventions
Nicotine 0 mg/mL, Nicotine 6 mg/mL, Nicotine 12 mg/mL, Nicotine 24 mg/mL, 'Menthol' flavor, 'Menthol/Mint' flavor, 'Green Apple' flavor, 'Watermelon' flavor, 'Unflavored'
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 30 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 4, 2024 · Synced Sep 5, 2026, 10:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Watermelon Dose Response Blood Pressure Study

NCT05892328
View directory record Official record
Conditions
Pre-hypertension, Cardiovascular Diseases
Interventions
Watermelon Flesh Dose 1, Watermelon Flesh Dose 2, Control
Other
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
25 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 5, 2026, 10:39 PM EDT
Completed Not applicable Interventional Results available

The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy.

NCT04675775
View directory record Official record
Conditions
Cirrhosis, Ascites, Liver Diseases, Frailty, Sarcopenia, Hepatic Encephalopathy
Interventions
Medically-tailored meals (MTM), Protein supplements, Nutrition education handout
Other · Dietary Supplement · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Sep 5, 2026, 10:39 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Acute Effects of Watermelon on Vascular Function and Serum Lycopene

NCT03608254
View directory record Official record
Conditions
Vascular Health of Postmenopausal Women
Interventions
100% watermelon juice
Other
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
65 Years to 70 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 13, 2022 · Synced Sep 5, 2026, 10:39 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Fresh Watermelon Consumption on Satiety and Cardiometabolic Health

NCT03380221
View directory record Official record
Conditions
Satiety
Interventions
Watermelon, Low fat cookies
Other
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2028
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 5, 2026, 10:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hydration Intervention in Children

NCT04265300
View directory record Official record
Conditions
Dehydration in Children
Interventions
Creative Roots
Dietary Supplement
Lead sponsor
University of Connecticut
Other
Eligibility
7 Years to 12 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 15, 2020 · Synced Sep 5, 2026, 10:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bioavailability and Pharmacokinetic Parameters of Watermelon (Rind, Flesh and Seeds) Polyphenols

NCT03365960
View directory record Official record
Conditions
Healthy Subjects
Interventions
Watermelon Rind, Watermelon Flesh, Watermelon Seeds, Placebo
Dietary Supplement
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
20 Years to 45 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Sep 5, 2026, 10:39 PM EDT
Active, not recruiting Not applicable Interventional

Watermelon/UBIQuinone Study

NCT04972552
View directory record Official record
Conditions
Kidney Transplantation
Interventions
coenzyme Q10, Watermelon diet, Usual Diet, Placebo
Dietary Supplement · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2025 · Synced Sep 5, 2026, 10:39 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Watermelon Juice on Heart Rate Recovery and Post-exercise Muscle Soreness

NCT03380195
View directory record Official record
Conditions
Heart Rate Recovery
Interventions
Watermelon juice, Sport drink, Sugar water, Water
Other
Lead sponsor
San Diego State University
Other
Eligibility
21 Years to 50 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2028
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 5, 2026, 10:39 PM EDT
Completed Phase 1Phase 2 Interventional

Watermelon Supplementation and Arterial Stiffness

NCT01185041
View directory record Official record
Conditions
Hypertension
Interventions
Watermelon Extract
Dietary Supplement
Lead sponsor
Florida State University
Other
Eligibility
45 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Mar 19, 2012 · Synced Sep 5, 2026, 10:39 PM EDT
Completed Not applicable Interventional Results available

Watermelon Focused Dietary Inflammatory Index Intervention

NCT03158740
View directory record Official record
Conditions
Inflammation, Diet Modification
Interventions
DII-Based Counseling System, general health education control
Behavioral
Lead sponsor
Michael D. Wirth
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Sep 5, 2026, 10:39 PM EDT
Completed Phase 1 Interventional Results available

Effects of E-cigarette Flavors on Youth TCORS 2.0

NCT03634839
View directory record Official record
Conditions
Nicotine Use Disorder
Interventions
Flavoring Agents, Nicotine
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 20 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Sep 5, 2026, 10:39 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Watermelon on Cardiometabolic Health

NCT07006636
View directory record Official record
Conditions
Cardiometabolic Health Indicators, Whole-body Antioxidant Capacity
Interventions
Watermelon Juice + liquid meal test at baseline, Sweetened placebo beverage +liquid meal test at baseline
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 5, 2026, 10:39 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Watermelon Consumption on Satiety and Digestive Health

NCT04096586
View directory record Official record
Conditions
Satiety
Interventions
Red juice, Watermelon juice
Other
Lead sponsor
San Diego State University
Other
Eligibility
10 Years to 55 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 5, 2026, 10:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Markers of Atherosclerosis in Overweight, Postmenopausal Women Following Daily Watermelon Consumption

NCT04015544
View directory record Official record
Conditions
Postmenopausal, Overweight and Obesity
Interventions
Watermelon
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
50 Years to 75 Years · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Boone, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Sep 5, 2026, 10:39 PM EDT