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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Web-based smoking cessation program Clear all
Completed Not applicable Interventional Results available

RCT of an Internet Cessation Program Plus Online Social Network for HIV+ Smokers

NCT02781090
View directory record Official record
Conditions
Tobacco Use Disorder, HIV
Interventions
PSFW+, AHA, Nicotine polacrilex
Behavioral · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
512 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
Baltimore, Maryland • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 3, 2023 · Synced Sep 2, 2026, 10:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing an MBI for Smoking Cessation and Alcohol Use Among Cancer Survivors

NCT07447635
View directory record Official record
Conditions
Smoking Cessation, Alcohol Use
Interventions
Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA), Quitline Support
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Phase 1Phase 2 Interventional

Positively Smoke Free on the Web (PSFW) for Smokers Living With HIV

NCT01570595
View directory record Official record
Conditions
Tobacco Use Cessation, Tobacco Cessation, Tobacco Use Disorder, Tobacco Dependence, Tobacco-Use Disorder, Virus, Human Immunodeficiency
Interventions
Web-Based Tailored Smoking Cessation Intervention, Standard of Care
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2014 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Not applicable Interventional Results available

Improving Adherence to Web-Based Cessation Programs: A Social Network Approach

NCT01544153
View directory record Official record
Conditions
Smoking Cessation
Interventions
WEB, Social Network, Nicotine Replacement Therapy (NRT)
Behavioral
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years and older
Enrollment
5,292 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 12, 2017 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Randomized Control Trial of Financial Incentives for Smoking Cessation

NCT01303081
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Individual Rewards, Fixed Deposits, Chosen Deposits, Competitive Deposits (Pari-Mutuel), Usual Care
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 1, 2012 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Text Messaging to Improve Adherence to Web-Based Cessation Treatment

NCT02585206
View directory record Official record
Conditions
Smoking Cessation
Interventions
Personalization, Integration, Dynamic Tailoring, Message Intensity, Optimal-Adherence Text
Behavioral
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years and older
Enrollment
1,485 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Not applicable Interventional

A Usability Study of a Smoking Cessation Decision Aid in People With a Recent First Episode of Psychosis

NCT01399112
View directory record Official record
Conditions
Smoking, Psychosis
Interventions
Web-based computer program
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
15 Years to 30 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Glen Oaks, New York
Source: ClinicalTrials.gov public record
Updated Jan 2, 2013 · Synced Sep 2, 2026, 10:50 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

BE Smokefree: Behavioral Economics Incentives to Engage Adolescents in Smoking Cessation

NCT03670264
View directory record Official record
Conditions
Smoking Cessation
Interventions
Quitline Incentive, Tobacco Cessation Incentive, Way to Health (WTH) Platform, Quitline Delivered Treatment
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
14 Years to 21 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 12, 2021 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Connecting Alaska Native People to Quit Smoking

NCT03645941
View directory record Official record
Conditions
Tobacco Use, Tobacco Smoking, Tobacco Use Cessation, Smoking Cessation, Smoking, Cigarette, Smoking, Tobacco, Smoking
Interventions
Facebook Group
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
19 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 7, 2022 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project Quit: Positive vs. Negative Offers of an Online Stop Smoking Program

NCT01923467
View directory record Official record
Conditions
Smoking Cessation
Interventions
Project Quit stop smoking program, Nicotine patches 21 mg
Behavioral · Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
767 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 14, 2015 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Not applicable Interventional Results available

Decision Support for Smoking Cessation in Young Adults With Severe Mental Illness

NCT01779440
View directory record Official record
Conditions
Mental Illness, Tobacco Smoking, Psychotic Disorders
Interventions
Electronic Decision Support System
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 30 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
3
States / cities
Manchester, New Hampshire • Nashua, New Hampshire • Glen Oaks, New York
Source: ClinicalTrials.gov public record
Updated Jun 26, 2018 · Synced Sep 2, 2026, 10:50 AM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.

NCT06053567
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Aerobic Exercise, Counseling, Nicotine patch
Behavioral · Drug
Lead sponsor
Jasper A. Smits
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Not applicable Interventional

Study on Sit to Quit Phone Intervention

NCT02840435
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Sit to Quit, Quit for Life
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Tobacco Tactics Website for Operating Engineers

NCT01124110
View directory record Official record
Conditions
Smoking, Tobacco Use Cessation
Interventions
Tobacco Tactics Web-Based Intervention, 1-800-QUIT-NOW Telephone Hotline
Behavioral · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
232 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 17, 2014 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Phase 4 Interventional

Web-based Smoking Cessation Intervention: Transition From Inpatient to Outpatient

NCT01277250
View directory record Official record
Conditions
Cigarette Smoking, Home Access to Internet and Email, Cognitively and Physically Able to Participate, English Speaking and Reading
Interventions
Web-based smoking cessation program
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
1,548 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 18, 2015 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Twitter-enabled Mobile Messaging for Smoking Relapse Prevention (Tweet2Quit)

NCT02823028
View directory record Official record
Conditions
Smoking Cessation
Interventions
NRT, Web Guide, Tweet2Quit
Drug · Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
21 Years to 59 Years
Enrollment
980 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
2
States / cities
Irvine, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Not applicable Interventional

Online Tai Chi Intervention to Promote Smoking Cessation Among Cancer Survivors

NCT05941858
View directory record Official record
Conditions
Cancer
Interventions
Smoking Cessation Intervention, Carbon Monoxide Measurement, Internet-Based Intervention, Survey Administration, Tai Chi
Behavioral · Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 2, 2026, 10:50 AM EDT
Not yet recruiting Phase 2 Interventional

DOSE-UP: Dose Optimization for Smoking and E-Cigarette Use Pharmacotherapy

NCT07754578
View directory record Official record
Conditions
Dual Use of Cigarettes and E-cigarettes
Interventions
Text- and web-based support, Nicotine Replacement Therapy (NRT, nicotine patch), Nicotine replacement therapy lozenge
Behavioral · Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Phase 2 Interventional

Internet-Based Nonsmoking Program for Postpartum Women

NCT02602730
View directory record Official record
Conditions
Cigarette Smoking, Smoking, Tobacco
Interventions
Break the Chain, Clearing the Air
Behavioral
Lead sponsor
Oregon Center for Applied Science, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
307 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 10, 2015 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Innovative Web-Based Intervention for Smoking Cessation Among College Students

NCT01982825
View directory record Official record
Conditions
Tobacco Use Cessation, Cigarette Smoking
Interventions
Online intervention arm, Online control arm
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 30 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 4, 2013 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Curbing Tobacco Use in Suburban and Rural Schools

NCT00513097
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Smoking Prevention Program, Focus Group, Survey
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
14 Years to 16 Years
Enrollment
1,289 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Way to Quit - Comparative Efficacy, Acceptance and Effectiveness of Health Incentive Structures

NCT01526265
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Usual Care, Individual Rewards, Fixed Deposits, Competitive Deposits (Pari-Mutuel), Collaborative Rewards
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
2,185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Sep 2, 2026, 10:50 AM EDT
Recruiting Not applicable Interventional

Remote Smoking Cessation in Hospitalized Cardiac Patients

NCT05738408
View directory record Official record
Conditions
Smoking Cessation
Interventions
Financial Incentives (FI) and Nicotine Replacement Therapy (NRT)
Behavioral
Lead sponsor
University of Vermont Medical Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 19, 2025 · Synced Sep 2, 2026, 10:50 AM EDT
Completed Not applicable Interventional Results available

My Mobile Advice Program: A Randomized Pilot Feasibility Study

NCT02136498
View directory record Official record
Conditions
Smoking Cessation, Medication Adherence
Interventions
Varenicline, Cognitive-behavioral self-help, MyMAP (My Mobile Advice Program)
Drug · Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 65 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 12, 2017 · Synced Sep 2, 2026, 10:50 AM EDT