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ClinicalTrials.gov public records Last synced Sep 30, 2026, 10:59 AM EDT

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Showing 25–48 of 1,100 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Weight Loss Intervention Clear all
Completed Not applicable Interventional

Food is Medicine: Pilot Study

NCT06797453
View directory record Official record
Conditions
Weight Loss
Interventions
Shared Medical Visits, Full Plate Living
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 90 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional Results available

Changing Lifestyles for Better Health

NCT00848757
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Intensive Lifestyle Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Exercise and Weight Loss on Cardiovascular Health

NCT01500356
View directory record Official record
Conditions
Cardiovascular Disease, Obesity
Interventions
Behavioral weight loss intervention, Diet Plus Moderate Exercise, Diet Plus High Exercise
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
383 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 25, 2017 · Synced Sep 30, 2026, 10:59 AM EDT
Recruiting Phase 1Phase 2 Interventional

A Self-Guided Mobile Intervention for Adults With Binge Eating and Obesity

NCT06817863
View directory record Official record
Conditions
Binge Eating Disorder Associated With Obesity, Binge Eating Disorder
Interventions
Digital
Other
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional

Families Improving Together (FIT) for Weight Loss

NCT01796067
View directory record Official record
Conditions
Overweight, Obese
Interventions
Motivational and Family Weight Loss, Basic Health Education, Online Intervention, Online Control
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
11 Years to 16 Years
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2019 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional

The Psychiatric Rehabilitation Approach to Weight Loss

NCT00572247
View directory record Official record
Conditions
Schizophrenic Disorders
Interventions
Psychiatric Rehabilitation Approach to Weight Loss
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 65 Years
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 7, 2012 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MIND Diet Intervention and Cognitive Decline

NCT02817074
View directory record Official record
Conditions
Cognitive Decline, Dementia, Alzheimer Disease, Vascular Dementia
Interventions
MIND Diet, Mild Weight Loss
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
65 Years to 84 Years
Enrollment
604 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
2
States / cities
Chicago, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 23, 2022 · Synced Sep 30, 2026, 10:59 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Piloting a Patient Navigator Program for Weight Loss

NCT06972381
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Navigator
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 75 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lifestyle Intervention Forever: Healthy Weight for Pregnancy and Birth (Pilot Study)

NCT01693666
View directory record Official record
Conditions
Pregnancy, Obesity, Weight Gain, Obstetric Complications
Interventions
Lifestyle intervention
Behavioral
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 2, 2015 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Insulin and the Polycystic Ovary Syndrome--Weight Reduction Study

NCT00436865
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Obesity
Interventions
Weight loss
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2017
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 30, 2018 · Synced Sep 30, 2026, 10:59 AM EDT
Completed No phase listed Observational

Gene x Behavior Interaction in the Look AHEAD Study

NCT01270763
View directory record Official record
Conditions
Obesity, Type 2 Diabetes
Interventions
Intensive lifestyle intervention, Diabetes support and education
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
45 Years to 74 Years
Enrollment
4,108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 18, 2015 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lifestyle Interventions for Seniors With Apnea

NCT01422863
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 18, 2017 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Change in Reward System Activation and Gut Microbiota Following RYGB and Sleeve Gastrectomy for Weight Loss vs. Control-Heads Up Ancillary

NCT02735564
View directory record Official record
Conditions
Bariatric Surgery Candidate
Interventions
Bariatric Surgery
Procedure
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
21 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diet Induced Weight Loss to Reduce Inflammation in Obese Women

NCT01699906
View directory record Official record
Conditions
Obesity
Interventions
Diet regimen to induce weight loss
Other
Lead sponsor
Rockefeller University
Other
Eligibility
40 Years to 70 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 5, 2014 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Reduction and Cognitive Health: Pilot Study Testing a Prolonged Testing Prolonged Fasting Among Obese, Stressed Mid-life Adults

NCT05388318
View directory record Official record
Conditions
Midlife Obese Adults With Cognitive Decline
Interventions
Prolonged nightly fasting, Health Education Control
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
40 Years to 59 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional

PILI 'Ohana Project: Partnerships to Overcome Obesity Disparities in Hawaii (3-Year Pilot)

NCT01042886
View directory record Official record
Conditions
Overweight, Obesity
Interventions
PILI 'Ohana Lifestyle Program, Standard Behavioral Weight Loss Maintenance Program
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
277 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Jan 6, 2010 · Synced Sep 30, 2026, 10:59 AM EDT
Not yet recruiting Phase 2 Interventional

A Study of Weight Loss Intervention With Tirzepatide and Progestin Intrauterine Device to Treat Endometrial Hyperplasia and Grade 1 Endometrial Cancer

NCT07349641
View directory record Official record
Conditions
Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia, FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma
Interventions
Medical Device Usage and Evaluation, Tirzepatide
Other · Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older · Female only
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Chicago, Illinois • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 30, 2026, 10:59 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Bariatric Embolization of Arteries for the Treatment of Nonalcoholic Steatohepatitis

NCT02933554
View directory record Official record
Conditions
Obesity, Weight Loss, Body Weight, Nonalcoholic Steatohepatitis, Nonalcoholic Fatty Liver Disease, NAFLD
Interventions
Embospheres Microspheres
Device
Lead sponsor
Keith Pereira, MD:
Other
Eligibility
22 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Sep 30, 2026, 10:59 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

EBT Fruit and Vegetable Prescription

NCT05028205
View directory record Official record
Conditions
Childhood Obesity, Obesity
Interventions
Prevention Plus
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
4 Years to 10 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional

Comparison of Weight Loss Programs for Individuals With Severe Obesity

NCT01330329
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Standard behavioral treatment, SBT + technology system (SBT+FIT)
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
21 Years to 55 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 20, 2012 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional Results available

Diabetes Prevention Translation: the Healthy Lifestyle Project

NCT01050205
View directory record Official record
Conditions
Diabetes, Cardiovascular Risk Factor
Interventions
Current Intervention, Delayed Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
223 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 25, 2017 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alternative Dietary Approaches Online to Promote Tracking

NCT05049005
View directory record Official record
Conditions
Diet Quality, Weight Loss
Interventions
Simplified dietary tracking
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 12, 2022 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional

Tailoring a Lifestyle Intervention to Address Obesity Disparities Among Men

NCT03037502
View directory record Official record
Conditions
Weight Loss, Obesity
Interventions
Tailor Made: Solutions for your health (A su Medida: Soluciones para su salud)
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
35 Years to 64 Years · Male only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Miami, Florida • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 23, 2021 · Synced Sep 30, 2026, 10:59 AM EDT
Completed Not applicable Interventional Results available

Just-in-time Adaptive Intervention Messaging in a Digital Weight Loss Intervention for Young Adults

NCT05625061
View directory record Official record
Conditions
Obesity, Overweight, Overweight and Obesity
Interventions
Core Behavioral Weight Loss (BWL) Intervention, Behavior Change Technique 1 Message (Action Planning), Behavior Change Technique 2 Message (Discrepancy between Current Behavior and Goal), Behavior Change Technique 3 Message (Feedback on Outcome of Behavior), Behavior Change Technique 4 Message (Social Support), Behavior Change Technique 5 Message (Social Comparison), Behavior Change Technique 6 Message (Social Reward), Behavior Change Technique 7 Message (Focus on Past Success)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 39 Years
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 30, 2026, 10:59 AM EDT