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ClinicalTrials.gov public records Last synced Oct 18, 2026, 12:53 PM EDT

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Showing 1–24 of 306 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Weight Loss Only Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Weight-Loss in African American Cancer Survivors in the Deep South

NCT03150381
View directory record Official record
Conditions
Weight Loss, Cancer
Interventions
Weight Loss Only, Weight Loss Plus, Control
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
369 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 16, 2018 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional

GoalTracker: Comparing Self-Monitoring Strategies for Weight Loss

NCT03254953
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss
Interventions
self-monitoring of body weight, self-monitoring of diet, weekly personalized feedback + lessons + action plans
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Oct 18, 2026, 12:53 PM EDT
Recruiting Not applicable Interventional

Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center

NCT06897982
View directory record Official record
Conditions
Prediabetic State, PreDiabetes, Health Knowledge, Attitudes, Practice, Nutrition, Healthy, Acceptability of Health Care, Obesity Prevention
Interventions
One-arm feasibility pilot of a nutrition intervention to recruit, engage, and retain DPP participants in the safety-net setting in Los Angeles
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Phase 2 Interventional Results available

Treatment-free Remission After Achieving Sustained MR4.5 on Nilotinib (ENESTop)

NCT01698905
View directory record Official record
Conditions
Chronic Myeloid Leukemia
Interventions
nilotinib
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 100 Years
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2025
U.S. locations
5
States / cities
Los Angeles, California • Beech Grove, Indiana • Baltimore, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional

Patient-centered Goal Setting in the National Diabetes Prevention Program

NCT05559515
View directory record Official record
Conditions
PreDiabetes
Interventions
NDPP-Flex, NDPP
Behavioral
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 18, 2026, 12:53 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Metabolism and Sleep Apnea Treatment

NCT05539716
View directory record Official record
Conditions
Obstructive Sleep Apnea, Fat Disorder
Interventions
PAP Therapy, Lifestyle Counseling Intervention
Device · Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 18, 2026, 12:53 PM EDT
Not yet recruiting No phase listed Observational

GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH and THRIVE Prospective Cohort Study

NCT07588984
View directory record Official record
Conditions
Obesity & Overweight, Weight Loss, Preventative Health, Body Weight, Cardiovascular Disease Risk Factor
Interventions
Noom Weight, Free Tier, Education-only control, Semaglutide, Tirzepatide, Microdose semaglutide, Microdose tirzepatide
Behavioral · Drug
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
2,310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 18, 2026, 12:53 PM EDT
Not listed Not applicable Interventional

Weight Loss and Gastrostomy Tube Care Outcomes in Head and Neck Cancer Patients With Gastrostomy Tube Placement

NCT02775721
View directory record Official record
Conditions
Malnutrition, Gastrostomy
Interventions
Nursing Education related to Gastrostomy Tube Care, Speech Therapy Education and Evaluation, Nutritional Therapy Education and Evaluation, Quality of Life Questionnaire C30 version 3, Quality of Life Questionnaire EORTC QLO - H&N35
Other
Lead sponsor
St. John Health System, Oklahoma
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 17, 2018 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional

Dyad Plus Effectiveness/Feasibility

NCT04036331
View directory record Official record
Conditions
Weight Loss, Pediatric Obesity, Overweight Adolescents, Parent-Child Relations, Family and Household
Interventions
Brenner FIT Standard, By Design Essentials, Dyad Plus
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
13 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 18, 2026, 12:53 PM EDT
Terminated Phase 4 Interventional Results available

EMI-EHP Weight Management and Type 2 Diabetes Pragmatic Trial

NCT04531176
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
Weight Management Program (WMP), Traditional care, Phentermine / Topiramate Extended Release Oral Capsule, naltrexone/bupropion extended-release, liraglutide 3.0 mg, Orlistat
Other · Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Single Anastomosis Duodenal Ileal Bypass (SADI) for Sleeve Revision

NCT04165694
View directory record Official record
Conditions
Bariatric Surgery Candidate, Severe Obesity
Interventions
Single Anastomosis Duodenal Ileal Bypass (SADI)
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 100 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reinforced Enhanced - Families Responsibility Education Support and Health

NCT02976636
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Family-based behavioral therapy, Parenting training
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
7 Years to 12 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 17, 2023 · Synced Oct 18, 2026, 12:53 PM EDT
Recruiting Phase 1Phase 2 Interventional

A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis

NCT03952637
View directory record Official record
Conditions
Lysosomal Diseases, Gangliosidosis, GM1
Interventions
AAV9-GLB1, Abdominal ultrasound, Rituximab, Sirolimus, Methylprednisolone, Prednisone, Audiology assessment with ABR, Bone density scan (DEXA), Electrocardiogram (EKG), Echocardiogram, Electroencephalogram (EEG) awake and extended overnight, Laboratory tests, Lumbar puncture, Brain MRI/MRS/fMRI, Neurocognitive testing, Neurology exam, PICC or other Central line placement, Skeletal survey, Skin biopsy, Speech and modified barium swallow study, Ophthalmology exam
Biological · Procedure · Drug + 3 more
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
6 Months to 12 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional Results available

Support and Tracking to Achieve Results (Project STAR)

NCT04116853
View directory record Official record
Conditions
Obesity
Interventions
ADAPTIVE Extended-Care Program, STATIC Extended-Care Program
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 18, 2026, 12:53 PM EDT
Not listed Phase 4 Interventional

Effects of Valsartan and Aliskiren on Hemostatic Indices in Hypertensive Diabetics

NCT01095822
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Aliskiren + Valsartan
Drug
Lead sponsor
HeartDrug Research LLC
Other
Eligibility
21 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 30, 2010 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Loss and Cognitive Function in Adults

NCT03685305
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Hypocaloric diet with hunger reduction strategy, Hypocaloric diet without hunger reduction strategy
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
50 Years to 75 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional

Inpatient Obesity Intervention With Phone Follow-up

NCT01920620
View directory record Official record
Conditions
Obesity
Interventions
Inpatient weight loss counseling, Motivational interviewing and troubleshooting via phone
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 20, 2016 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional

Mechanisms of Diabetes Relapse After Bariatric Surgery

NCT01516320
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Roux-en-Y Gastric Bypass, Laparoscopic adjustable gastric banding, Vertical Sleeve Gastrectomy
Procedure
Lead sponsor
Blandine Laferrere
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Phase 2 Interventional Results available

Adaptive Nutrition and Exercise Weight Loss (A-NEW) Study

NCT04499950
View directory record Official record
Conditions
Breast Cancer, Overweight or Obesity
Interventions
Contrave, Behavioral Weight Loss
Drug · Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Female only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CHAT at HOME Pilot Study

NCT03661918
View directory record Official record
Conditions
Childhood Obesity
Interventions
In-Person First Session, Second Caregiver, WiFi-enabled Scale, 10 Core Coaching Calls Only
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
8 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional Results available

Coaching Veterans to Healthy Weights and Wellness

NCT00967668
View directory record Official record
Conditions
Obesity
Interventions
Small change approach to improve physical activity and diet, MOVE! Usual Care
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
481 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Ann Arbor, Michigan • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 24, 2015 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study of Time Restricted Feeding as a Weight Loss Intervention

NCT03571048
View directory record Official record
Conditions
Obesity
Interventions
Reduced Calorie Diet (RCD), Time Restricted Feeding (TRF)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 50 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 25, 2022 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PilAm Go4Health Weight Loss Program to Prevent Heart Disease

NCT02290184
View directory record Official record
Conditions
Type2 Diabetes
Interventions
PilAm Go4Health Weight-loss Program, Active Control
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Oct 18, 2026, 12:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Parents as the Agent of Change for Childhood Obesity

NCT01197443
View directory record Official record
Conditions
Obesity
Interventions
Parent-only Group, Parent + Child Group
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
8 Years to 12 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Oct 18, 2026, 12:53 PM EDT