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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Weight Loss Specialist Clear all
Completed Phase 2 Interventional Results available

eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk

NCT04437485
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms, Type 2 Diabetes, PreDiabetes, Insulin Resistance
Interventions
Good Days Ahead (GDA), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications, Active Control
Behavioral · Drug · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional Results available

Rural Engagement in Primary Care for Optimizing Weight Reduction

NCT02456636
View directory record Official record
Conditions
Obesity
Interventions
Fee-for-Service Model (FFS, In clinic individual visits), Patient Centered Medical Home (PCMH, In clinic group visits), Disease Management (DM, Phone group visits)
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
20 Years to 75 Years
Enrollment
1,432 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 6, 2020 · Synced Sep 25, 2026, 4:58 PM EDT
Recruiting Phase 2 Interventional

Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients

NCT04721873
View directory record Official record
Conditions
Colitis, Ulcerative, Obesity
Interventions
Phentermine-Topiramate, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 15, 2023 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study of the HWL Program

NCT03439579
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Home weight loss program
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 8, 2018 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Phase 2 Interventional

Can Diet- and Exercise-Induced Weight Loss Improve Asthma Control in Adults?

NCT00901095
View directory record Official record
Conditions
Asthma, Obesity
Interventions
Lifestyle intervention
Behavioral
Lead sponsor
Palo Alto Medical Foundation
Other
Eligibility
18 Years to 70 Years
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
8
States / cities
Fremont, California • Hayward, California • Novato, California + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 18, 2014 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

NC Works4Health: Reducing Chronic Disease Risks in Socioeconomically Disadvantaged, Unemployed Populations

NCT04815278
View directory record Official record
Conditions
Diabetes, Chronic Disease, Psychological Distress
Interventions
Immediate Chronic Disease Prevention Program (CDPP), Workplace Equity, Job and Health Supports Employer Intervention, Delayed, attenuated Chronic Disease Prevention Program (CDPP)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 64 Years
Enrollment
455 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 25, 2026, 4:58 PM EDT
Enrolling by invitation Not applicable Interventional

A Study to Evaluate Primary Care Treatment for Adolescent Eating Disorders

NCT05814653
View directory record Official record
Conditions
Eating Disorders
Interventions
Family Based Treatment-Primary Care, Family-Based Treatment
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
7 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional

Effects of Diet and Exercise on Ductal Carcinoma in Situ

NCT02224807
View directory record Official record
Conditions
Ductal Carcinoma In Situ, Breast Cancer
Interventions
Active Comparator: Progressive Resistance Training (PRT) and a healthy diet, Experimental: PRT and a healthy diet, plus weight loss
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional

Dyad Plus Effectiveness/Feasibility

NCT04036331
View directory record Official record
Conditions
Weight Loss, Pediatric Obesity, Overweight Adolescents, Parent-Child Relations, Family and Household
Interventions
Brenner FIT Standard, By Design Essentials, Dyad Plus
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
13 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Phase 4 Interventional Results available

Real World Effectiveness of Combining an Employer-based Weight Management Program With Medication for Chronic Weight Management in Employees With Obesity

NCT03799198
View directory record Official record
Conditions
Obesity
Interventions
Weight Management Program (WMP), Medication for chronic weight management (Rx)
Other · Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 13, 2022 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional

BfedBwell Proof-of-Concept Pilot

NCT06191666
View directory record Official record
Conditions
Cancer Survivorship, Obesity, Overweight
Interventions
Group-based education and discussion, Individual 1:1 counseling, Group based behavioral skills development and cooking demonstrations, BfitBwell
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional Results available

Coach to Fit Weight Loss Intervention for Individuals With Serious Mental Illness

NCT04560335
View directory record Official record
Conditions
Serious Mental Illness
Interventions
Coach to FIt, Treatment as Usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
257 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 25, 2026, 4:58 PM EDT
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Metabolic Surgery for Atrial Fibrillation Elimination

NCT07027969
View directory record Official record
Conditions
Atrial Fibrillation, Obesity and Obesity-related Medical Conditions
Interventions
Roux-en-Y Gastric Bypass or Sleeve Gastrectomy, Anti-Obesity Medication (AOM) treatment
Procedure · Drug
Lead sponsor
Ali Aminian
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional Results available

Weight Loss Intervention for Individuals With Lower Extremity Amputation

NCT02085785
View directory record Official record
Conditions
Lower Extremity Amputation
Interventions
Coached group, Self-directed control group, Screened only
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 69 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Sep 25, 2026, 4:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Assessing the Impact of myHealth Rewards Program-related Communications on Enrollment: Replication

NCT04289623
View directory record Official record
Conditions
Health Promotion, Wellness Program
Interventions
Email, Loss frame, Testimonial (medical expert), Testimonial (rank-and-file), Social norms (percentage), Social norms (number)
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
13,546 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Sep 25, 2026, 4:58 PM EDT
Recruiting Not applicable Interventional

Advanced Fibrosis Detection for MASLD in Primary Care

NCT07159386
View directory record Official record
Conditions
Metabolic Dysfunction-associated Steatotic Liver Disease
Interventions
EHR alert
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional

Weight Loss Referral for Healthier Survivorship in Obese Stage I-II Endometrial Cancer Survivors or Atypical Hyperplasia

NCT02342730
View directory record Official record
Conditions
Complex Endometrial Hyperplasia With Atypia, Stage IA Uterine Corpus Cancer, Stage IB Uterine Corpus Cancer, Stage II Uterine Corpus Cancer
Interventions
Weight Loss Specialist, Quality-of-Life Assessment, Medical Chart Review
Behavioral · Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 18, 2018 · Synced Sep 25, 2026, 4:58 PM EDT
Active, not recruiting No phase listed Observational

Weight Loss Management in Endometrial Cancer Survivors

NCT06877572
View directory record Official record
Conditions
Endometrial Cancer Survivors, Weight Management, Early Stage Endometrial Cancer
Interventions
Weight loss with pharmacotherapy, Weight loss without pharmacotherapy
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional

Developing an Adaptive Lifestyle Intervention Program in Family Medicine Clinics

NCT04392284
View directory record Official record
Conditions
Insulin Resistance, Obesity, Diabetes, Hypertension, Dyslipidemias, Metabolic Syndrome
Interventions
Diet Counseling, Exercise Counseling
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional Results available

Peer-Led Healthy Lifestyle Program in Supportive Housing

NCT02175641
View directory record Official record
Conditions
Obesity
Interventions
Peer-Led Group Lifestyle Balance, Usual Care Services
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 30, 2021 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional

Changing Healthy Outcomes In Clinic Environments

NCT00674518
View directory record Official record
Conditions
Obesity, Physical Inactivity, Diabetes
Interventions
One on one counseling, Group/team - based health education, PACE physician counseling
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
30 Years to 65 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional

A Coordinated Parent/Child Dyad Weight Loss Intervention: Dyad Plus (Feasibility)

NCT03811743
View directory record Official record
Conditions
Weight Loss, Pediatric Obesity
Interventions
Brenner FIT, By Design, Coordination
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
13 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 25, 2026, 4:58 PM EDT
Active, not recruiting Not applicable Interventional

Rural Engagement in TelemedTeam for Options in Obesity Treatment Solutions

NCT05710510
View directory record Official record
Conditions
Obesity, Obesity, Morbid
Interventions
Local Care + Model, Team Care Model
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
20 Years to 75 Years
Enrollment
560 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Sep 25, 2026, 4:58 PM EDT
Completed Not applicable Interventional

Preventing Diabetes

NCT05395377
View directory record Official record
Conditions
PreDiabetes
Interventions
Registered Dietitian/Nutritionist, Diabetes Prevention Program, Weight Watchers, Reimagined, DPP or RDN Counseling + Medication, Bariatric Surgery Evaluation
Behavioral · Other
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 26, 2022 · Synced Sep 25, 2026, 4:58 PM EDT