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Showing 1–24 of 199 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 2 Interventional Accepts healthy volunteers Results available

Semaglutide Use in Elderly Obese Patients

NCT05302596
View directory record Official record
Conditions
Obesity, Aging
Interventions
Semaglutide Pen Injector
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
65 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using Partners to Enhance Long-Term Weight Loss

NCT03801174
View directory record Official record
Conditions
Obesity
Interventions
Partner-assisted intervention, Patient-only intervention
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 74 Years
Enrollment
346 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Building an Evidence Base for Weight Loss Strategies Among Those With Chronic SCI-The GLB-SCI+

NCT03874988
View directory record Official record
Conditions
Spinal Cord Injuries, Obesity, Weight Loss, Diet Modification
Interventions
Portion-Controlled Meals, Enhanced Self-Monitoring, GLB-SCI+
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alternative Dietary Approaches Online to Promote Tracking

NCT05049005
View directory record Official record
Conditions
Diet Quality, Weight Loss
Interventions
Simplified dietary tracking
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional

Mechanisms of Diabetes Relapse After Bariatric Surgery

NCT01516320
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Roux-en-Y Gastric Bypass, Laparoscopic adjustable gastric banding, Vertical Sleeve Gastrectomy
Procedure
Lead sponsor
Blandine Laferrere
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

NOURISH: Nourishing Our Understanding of Role Modeling to Improve Support and Health

NCT00628030
View directory record Official record
Conditions
Pediatric Obesity
Interventions
NOURISH, Wellness Group
Behavioral · Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 18, 2015 · Synced Sep 17, 2026, 5:55 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Evaluation of the Healthy Lifestyle Program on Cognitive Outcomes

NCT03926481
View directory record Official record
Conditions
Obesity
Interventions
Evaluate Healthy Lifestyle Program on cognitive outcomes
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
65 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Low Intensity Weight Loss for Young Adults

NCT02736981
View directory record Official record
Conditions
Obesity
Interventions
Behavioral Weight Loss (BWL), BWL + Autonomous Motivation, BWL + Extrinsic Motivation
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 25 Years
Enrollment
382 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 6, 2023 · Synced Sep 17, 2026, 5:55 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Remote Approaches for Optimizing Weight Loss (Elevate Weight Loss Trial)

NCT06875622
View directory record Official record
Conditions
Obesity/therapy
Interventions
Automated online weight loss program, Individual coaching, Group-based, videoconference-delivered weight loss
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
490 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Sep 17, 2026, 5:55 PM EDT
Not listed Not applicable Interventional

An ACT-enhanced Weight Management and Fitness Program for Navy Personnel

NCT03029507
View directory record Official record
Conditions
Obesity, Overweight
Interventions
ACT Enhanced ShipShape, Standard ShipShape (SS)
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years to 69 Years
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional

Weight Inclusive and Adaptive Strategies to Enhance Cardiometabolic Health in Black Adults

NCT06284681
View directory record Official record
Conditions
Obesity, Prehypertension, Hypertension, PreDiabetes, Type 2 Diabetes, Dyslipidemia
Interventions
Weight-focused health coaching, Weight-neutral health coaching, Intensify lifestyle approach, Augment with enhanced medical management
Behavioral · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 17, 2026, 5:55 PM EDT
Terminated Not applicable Interventional Results available

Multimodal Treatment Strategy for Cancer Cachexia

NCT00625742
View directory record Official record
Conditions
Advanced Cancer, Cachexia
Interventions
Graded Resistance Training, Aerobic Exercise, Melatonin, Juven, Atenolol, Ibuprofen
Behavioral · Drug · Dietary Supplement
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2016 · Synced Sep 17, 2026, 5:55 PM EDT
Recruiting Not applicable Interventional

The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer

NCT05780814
View directory record Official record
Conditions
Breast Cancer, Insomnia, Weight Gain
Interventions
Cognitive-Behavioral Therapy for Insomnia (CBT-I), Sleep Education Control (EDU)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • Lutherville, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 17, 2026, 5:55 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Study of BMF-650 in Otherwise Healthy Overweight or Obese Adult Participants

NCT07223216
View directory record Official record
Conditions
Obesity
Interventions
BMF-650
Drug
Lead sponsor
Biomea Fusion Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Phase 2 Interventional Results available

SMART Use of Medication for the Treatment of Adolescent Severe Obesity

NCT04007393
View directory record Official record
Conditions
Adolescent Obesity
Interventions
Lifestyle Modification Therapy (LSMT), Phentermine Pill, Topiramate Pill, Placebo
Behavioral · Drug
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 17 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional Results available

Weight Loss Intervention for Individuals With Lower Extremity Amputation

NCT02085785
View directory record Official record
Conditions
Lower Extremity Amputation
Interventions
Coached group, Self-directed control group, Screened only
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 69 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Internet Obesity Treatment Enhanced With Motivational Interviewing

NCT01232699
View directory record Official record
Conditions
Obesity
Interventions
Internet Obesity Treatment, Internet Obesity Treatment with MI, Contingent MI
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
495 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
2
States / cities
Little Rock, Arkansas • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Dec 23, 2018 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional Results available

Cell Phone Intervention in Young Adults

NCT01092364
View directory record Official record
Conditions
Obesity
Interventions
Behavioral weight loss intervention
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 35 Years
Enrollment
365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 12, 2017 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional

The Effects of a Mobile Health Intervention and Health Coach Text Messaging on Cardiovascular Risk of Older Adults

NCT03720327
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiovascular Risk Factor
Interventions
Get FIT+
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
60 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
5
States / cities
Anaheim, California • Irvine, California • Orange, California + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2022 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional

Exercise and Weight Loss for Improving Mobility in Older Adults Who Are Obese

NCT00119795
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Metabolic Syndrome X, Obesity
Interventions
Exercise, Weight Loss, Health Education Control
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years to 79 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
3
States / cities
Greensboro, North Carolina • Lexington, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multicenter Endoscopic Sleeve Gastrectomy (ESG) Trial (MERIT Trial)

NCT03406975
View directory record Official record
Conditions
Obesity, Hypertension, Diabetes Mellitus, Type 2
Interventions
Overstitch Endoscopic Suture System, Lifestyle Intervention
Device · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years to 65 Years
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
9
States / cities
Orlando, Florida • Chicago, Illinois • Evanston, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Sep 17, 2026, 5:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lose 2 Win A Novel Method to Motivate Weight Loss Maintenance Among College Students

NCT02021383
View directory record Official record
Conditions
Overweight, Obese
Interventions
Bi-weekly in person meetings with a Registered Dietician, Financial incentives for weight loss maintenance
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 24 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 12, 2019 · Synced Sep 17, 2026, 5:55 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

DS vs SIPS-Bariatric Surgery Comparasion

NCT03236142
View directory record Official record
Conditions
Bariatric Surgery Candidate
Interventions
SIPS Operation, Standard Duodenal Switch Operation
Procedure
Lead sponsor
Reading Health System
Other
Eligibility
20 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
West Reading, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 4, 2018 · Synced Sep 17, 2026, 5:55 PM EDT
Active, not recruiting Not applicable Interventional

Safety and Efficacy of Ketogenic Diet for Promoting Weight Loss in Obese Individuals With Compensated NASH Cirrhosis

NCT04383951
View directory record Official record
Conditions
NASH - Nonalcoholic Steatohepatitis, Cirrhosis, Liver
Interventions
Dietary consult for participants in the ketogenic diet arm, Dietary consult for participants in the standard of care arm
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 17, 2026, 5:55 PM EDT