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ClinicalTrials.gov public records Last synced Oct 5, 2026, 3:19 AM EDT

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Showing 121–144 of 199 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Weight loss Only Intervention Clear all
Active, not recruiting Not applicable Interventional

Miro-randomized Trial for Optimizing a JITAI to Reduce Dietary Lapses in Obesity Treatment

NCT04784585
View directory record Official record
Conditions
Obesity
Interventions
JITAI Enhanced Education Intervention Option, JITAI Self-Efficacy Intervention Option, JITAI Motivation Intervention Option, JITAI Self-Regulation Intervention Option, JITAI Generic Risk Alert Intervention Option (Active Comparator), Online Behavioral Obesity Treatment, JITAI No Treatment Intervention Option
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 5, 2026, 3:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PilAm Go4Health Weight Loss Program to Prevent Heart Disease

NCT02290184
View directory record Official record
Conditions
Type2 Diabetes
Interventions
PilAm Go4Health Weight-loss Program, Active Control
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Oct 5, 2026, 3:19 AM EDT
Completed Not applicable Interventional

PATH to Health: An Exploration of Digital Behavioral Weight Loss Approaches

NCT05929469
View directory record Official record
Conditions
Overweight, Obesity, Overweight and Obesity
Interventions
App, Fully Automated Kick-Off, Human-Enhanced Kick-Off, Check-In, Counseling
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 30, 2024 · Synced Oct 5, 2026, 3:19 AM EDT
Recruiting Phase 2 Interventional

A Mobile Intervention to Reduce Pain and Improve Health-III

NCT06623669
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis, Obesity and Overweight, Inactivity
Interventions
MORPH, Measurement Only
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
65 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 5, 2026, 3:19 AM EDT
Completed Phase 4 Interventional Results available

Lifestyle Modification and Liraglutide

NCT02911818
View directory record Official record
Conditions
Obesity
Interventions
CMS-recommended lifestyle counseling, Liraglutide 3.0mg, Portion-Controlled Diet, Placebo Oral Tablet, Phentermine 15 MG, Extension Study CMS-recommended lifestyle counseling
Behavioral · Drug · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2019 · Synced Oct 5, 2026, 3:19 AM EDT
Completed Not applicable Interventional

The Retrain Your Brain for Healthy Eating Study

NCT05203718
View directory record Official record
Conditions
Obesity
Interventions
Food Response Training (FRT)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 25, 2025 · Synced Oct 5, 2026, 3:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Women In Steady Exercise Research (WISER) Survivor Trial

NCT01515124
View directory record Official record
Conditions
Lymphedema
Interventions
Exercise Intervention, Weight Loss Intervention
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
Up to 80 Years · Female only
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 10, 2022 · Synced Oct 5, 2026, 3:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Single Arm Trial of a Multi-component Commercial Digital Weight Loss Program

NCT04302389
View directory record Official record
Conditions
Weight Loss
Interventions
myWW App, Virtual Workshops, and Private Facebook Group
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 75 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 5, 2026, 3:19 AM EDT
Completed Not applicable Interventional Results available

Daily Caloric Restriction and Intermittent Fasting in Overweight and Obese Adults With Autosomal Dominant Polycystic Kidney Disease

NCT03342742
View directory record Official record
Conditions
Polycystic Kidney, Autosomal Dominant
Interventions
Weight Loss
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Oct 5, 2026, 3:19 AM EDT
Not listed Not applicable Interventional

Pilot of Virtual Health Coaching Utilizing Lifestyle for Under-Resourced Patients With Type II Diabetes

NCT04872647
View directory record Official record
Conditions
Type2 Diabetes
Interventions
Phone-Based Health Coaching Utilizing Lifestyle Action Plans
Behavioral
Lead sponsor
Beacon Health System
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
South Bend, Indiana
Source: ClinicalTrials.gov public record
Updated May 4, 2021 · Synced Oct 5, 2026, 3:19 AM EDT
Completed Not applicable Interventional

A Coordinated Parent/Child Dyad Weight Loss Intervention: Dyad Plus (Feasibility)

NCT03811743
View directory record Official record
Conditions
Weight Loss, Pediatric Obesity
Interventions
Brenner FIT, By Design, Coordination
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
13 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 5, 2026, 3:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimal Timing of Exercise Initiation Within a Lifestyle Weight Loss Program

NCT01985568
View directory record Official record
Conditions
Obesity
Interventions
Sequential BT, Standard BT
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 5, 2026, 3:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of a Structured Parent Intervention on Adolescent Weight Loss Modification Program.

NCT02086851
View directory record Official record
Conditions
Pediatric Obesity, Impact of Parent Intervention on Adolescent Weight Loss
Interventions
Lifestyle Intervention, Parent Motivational Interviewing
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
11 Years to 16 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Henrico, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 11, 2016 · Synced Oct 5, 2026, 3:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Respiratory Effects of Obesity in Children

NCT03376880
View directory record Official record
Conditions
Childhood Obesity
Interventions
1 year follow-up testing
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
8 Years to 12 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 5, 2026, 3:19 AM EDT
Completed Not applicable Interventional Results available

Support and Tracking to Achieve Results (Project STAR)

NCT04116853
View directory record Official record
Conditions
Obesity
Interventions
ADAPTIVE Extended-Care Program, STATIC Extended-Care Program
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 5, 2026, 3:19 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Aging, Geriatric Syndromes and Clonal Hematopoiesis

NCT02604563
View directory record Official record
Conditions
Geriatrics, Aged, Geriatric Syndromes, Cardiovascular Diseases
Interventions
Cognitive Assessment, Activities of Daily Living Questionnaire, Instrumental Activities of Daily Living, subscale of the OARS, Karnofsky Self-reported Performance Rating Scale, Number of Falls, Physical Health Section, subscale of the OARS, MOS Social Activity Survey, Unintentional Weight Loss, Peripheral Blood Draw, Buccal Swab, Heart Health and Smoking History from BRFSS questionnaire, Gait Speed, Grip Strength, Height and Weight measurements, Blood pressure measurement, Optional bone marrow biopsy, Blood draw for trauma measurements, Femur head donation, Knee bone fragments, Bone marrow aspirate
Other · Genetic · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
50 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2030
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 5, 2026, 3:19 AM EDT
Recruiting Phase 1Phase 2 Interventional

A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis

NCT03952637
View directory record Official record
Conditions
Lysosomal Diseases, Gangliosidosis, GM1
Interventions
AAV9-GLB1, Abdominal ultrasound, Rituximab, Sirolimus, Methylprednisolone, Prednisone, Audiology assessment with ABR, Bone density scan (DEXA), Electrocardiogram (EKG), Echocardiogram, Electroencephalogram (EEG) awake and extended overnight, Laboratory tests, Lumbar puncture, Brain MRI/MRS/fMRI, Neurocognitive testing, Neurology exam, PICC or other Central line placement, Skeletal survey, Skin biopsy, Speech and modified barium swallow study, Ophthalmology exam
Biological · Procedure · Drug + 3 more
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
6 Months to 12 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 5, 2026, 3:19 AM EDT
Not yet recruiting Not applicable Interventional

Optimization of Dietary Adherence in a Mobile Weight Loss Intervention

NCT07582536
View directory record Official record
Conditions
Overweight and/or Obesity
Interventions
Core, Switch to Simplified Diet Monitoring, Goal Autonomy/Planning, Just-in-time (JIT) Messaging, Coach Sessions
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
580 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 5, 2026, 3:19 AM EDT
Completed Not applicable Interventional

Epidemiology and Care of Comorbid Obesity and Depression

NCT00169273
View directory record Official record
Conditions
Obesity, Depression
Interventions
Structured behavioral weight loss group, Weight loss and cognitive-behavioral depression group
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 13, 2017 · Synced Oct 5, 2026, 3:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Increased Dietary Protein Intake During GLP-1 Medication Use (in Middle-aged Women With Overweight/Obesity)

NCT07480109
View directory record Official record
Conditions
Obesity, Women (Between 30 to 60 Years Old)
Interventions
Protein Rich Foods
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
30 Years to 60 Years · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 5, 2026, 3:19 AM EDT
Active, not recruiting Not applicable Interventional

Bariatric Surgery Versus Diet Alone in the Bile Acid Pathway and Weight Loss

NCT03238794
View directory record Official record
Conditions
Obesity
Interventions
Roux-En-Y Gastric Bypass, Low-calorie Diet
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 5, 2026, 3:19 AM EDT
Completed Not applicable Interventional

Web-Based Weight Loss & Weight Maintenance Intervention for Older Rural Women, Also Known as Women Weigh-in for Wellness

NCT01307644
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Experimental: Web-based only (WO) weight intervention, Experimental: WO plus peer-led discussion board (WD), Experimental: WO & professional email counseling (WE)
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
40 Years to 69 Years · Female only
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Oct 5, 2026, 3:19 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Chrononutrition and Adolescent Weight Control

NCT04256863
View directory record Official record
Conditions
Adolescent Obesity, Diet, Weight Loss, Sleep
Interventions
Breakfast / Lunch, Dinner (DIN)
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 5, 2026, 3:19 AM EDT
Not listed Not applicable Interventional

Peer-led and Telehealth Comparative Effectiveness Research (CER) Adoption for Diabetes Prevention and Management

NCT01307137
View directory record Official record
Conditions
Diabetes, Pre-diabetes
Interventions
Peer-led intervention, Telehealth Intervention
Behavioral
Lead sponsor
South Florida Veterans Affairs Foundation for Research and Education
Federal
Eligibility
60 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 2, 2011 · Synced Oct 5, 2026, 3:19 AM EDT