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Showing 1–24 of 64 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Weight loss core Clear all
Completed Phase 2 Interventional Results available

eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk

NCT04437485
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms, Type 2 Diabetes, PreDiabetes, Insulin Resistance
Interventions
Good Days Ahead (GDA), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications, Active Control
Behavioral · Drug · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Sep 28, 2026, 1:12 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Healthy Eating and Active Living Taught at Home (HEALTH) Dissemination & Implementation (D&I)

NCT03758638
View directory record Official record
Conditions
Obesity
Interventions
Healthy Eating & Active Living Taught at Home, Usual Care
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 28, 2026, 1:12 AM EDT
Completed Not applicable Interventional

Minnesota Medicaid Incentives to Prevent Chronic Disease

NCT02422420
View directory record Official record
Conditions
Prediabetic State
Interventions
Financial Incentives
Behavioral
Lead sponsor
Minnesota Department of Human Services
Government
Eligibility
18 Years to 74 Years
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 17, 2016 · Synced Sep 28, 2026, 1:12 AM EDT
Active, not recruiting Not applicable Interventional

The Inspiring Action to Prevent Diabetes Intervention

NCT06001801
View directory record Official record
Conditions
PreDiabetes
Interventions
Diabetes Prevention Program, INSPIRA
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Sep 28, 2026, 1:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Weight Management Study

NCT00851201
View directory record Official record
Conditions
Obesity, Diabetes
Interventions
Intensive lifestyle, Standard intervention
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
7 Years to 12 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 17, 2017 · Synced Sep 28, 2026, 1:12 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Pilot Factorial Trial of an Integrated Lifestyle Intervention

NCT06116435
View directory record Official record
Conditions
Physical Inactivity, Overweight and Obesity
Interventions
Prevent T2, Move group-based classes, Fitness Membership, Mental Imagery, Move 1:1 Support
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Sep 28, 2026, 1:12 AM EDT
Completed Not applicable Interventional

Recruiting and Retaining Young Adults in Behavioral Weight Loss Treatment

NCT01889082
View directory record Official record
Conditions
Obesity
Interventions
Behavioral Weight Loss Intervention for Young Adults
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 25 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 17, 2014 · Synced Sep 28, 2026, 1:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Delicious Eating for Life in Southern Homes

NCT04302727
View directory record Official record
Conditions
Weight Loss, Diet, Healthy, Cardiovascular Risk Factor
Interventions
Med-South Weight Loss Intervention, WW
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 28, 2026, 1:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Loss and Maintenance for Rural, African American Communities of Faith (The WORD)

NCT02169947
View directory record Official record
Conditions
Obesity
Interventions
Weight loss core, Weight loss core plus maintenance
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
425 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Mar 28, 2018 · Synced Sep 28, 2026, 1:12 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Developing a Weight Management Class as a Recruitment Tool for an Online Weight Loss Program to Rural Illinois Residents

NCT06406985
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Weight-loss through dietary and lifestyle changes
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 2, 2025 · Synced Sep 28, 2026, 1:12 AM EDT
Completed Not applicable Interventional

Prevention of Diabetes Using Mobile-enabled, Virtual Delivery of the National Diabetes Prevention Program

NCT03865342
View directory record Official record
Conditions
PreDiabetes
Interventions
Noom Coach DPP
Behavioral
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years and older
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2023 · Synced Sep 28, 2026, 1:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SMART Weight Loss Management

NCT02997943
View directory record Official record
Conditions
Weight Loss
Interventions
Step 1 Treatment: APP, Step 1 Treatment: APP + Coaching, Step 2 Treatment Strategy: Modest Step-up, Step 2 Treatment Strategy: Vigorous Step-up
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Sep 28, 2026, 1:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Remote Dietary Counseling to Promote Healthy Diet and Blood Pressure

NCT03700710
View directory record Official record
Conditions
Blood Pressure, High Blood Pressure, Dietary Modification, Overweight and Obesity
Interventions
Self-Guided Approach, Dietitian-led Approach
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
187 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Danville, Pennsylvania • Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced Sep 28, 2026, 1:12 AM EDT
Not yet recruiting Not applicable Interventional

Optimization of Dietary Adherence in a Mobile Weight Loss Intervention

NCT07582536
View directory record Official record
Conditions
Overweight and/or Obesity
Interventions
Core, Switch to Simplified Diet Monitoring, Goal Autonomy/Planning, Just-in-time (JIT) Messaging, Coach Sessions
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
580 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 28, 2026, 1:12 AM EDT
Not yet recruiting Not applicable Interventional

Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans

NCT07560969
View directory record Official record
Conditions
Diabetes, Physical Activity, Food Security, Nutrition Security
Interventions
Culturally-tailored, enhanced adaption of Diabetes Prevention Program
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 28, 2026, 1:12 AM EDT
Active, not recruiting Not applicable Interventional

Becoming United in Lifestyle Decisions

NCT05796141
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Core Behavioral Weight Loss (BWL) intervention, Dyadic Action Planning, Joint Feedback, Autonomy Support Training, Home Environment Modifications
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 75 Years
Enrollment
762 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 28, 2026, 1:12 AM EDT
Recruiting Not applicable Interventional

Fast In-Bed Tracking (FIT) System Lifestyle Intervention is a Clinical Trial of a Bed Scale Device. Overweight Wheelchair Users Will Complete a Weight Loss Program, Half Get Scales at Baseline, Half at Month 6 Those Who Receive the Bed Scales at Baseline Are Expected to Have Increased Weight Loss

NCT07141342
View directory record Official record
Conditions
Disability Physical, Wheelchair, Obesity; Overweight
Interventions
The Fast In-Bed Tracking System (FIT) Weight Scale, Group Lifestyle Balance Adapted for Individuals with Impaired Mobility (GLB-AIM) intervention
Device · Behavioral
Lead sponsor
Jonathan Pearlman
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 28, 2026, 1:12 AM EDT
Recruiting Not applicable Interventional

FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)

NCT06724406
View directory record Official record
Conditions
Obesity and Overweight, Diabetes Mellitus, Weight Loss, Behavior Change
Interventions
Family Skills Training Session Quantity: 5, Family Skills Training Session Mode: In-person, Family Skills Training Content: Communication, Family Skills Training Content: Cohesion, Family Skills Training Session Quantity: 10, Family Skills Training Session Mode: Online, Family Skills Training Content: No Communication, Family Skills Training Content: No Cohesion
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Sep 28, 2026, 1:12 AM EDT
Completed Not applicable Interventional Results available

Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention

NCT05715242
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss, Health Behavior
Interventions
Core Behavioral Weight Loss Intervention, Easier Step Goal, Harder Step Goal, Easier Calorie Goal, Harder Calorie Goal, Easier Eating Window Goal, Harder Eating Window Goal, Easier Red Zone Food Goal, Harder Red Zone Food Goal
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 28, 2026, 1:12 AM EDT
Completed Not applicable Interventional Results available

Just-in-time Adaptive Intervention Messaging in a Digital Weight Loss Intervention for Young Adults

NCT05625061
View directory record Official record
Conditions
Obesity, Overweight, Overweight and Obesity
Interventions
Core Behavioral Weight Loss (BWL) Intervention, Behavior Change Technique 1 Message (Action Planning), Behavior Change Technique 2 Message (Discrepancy between Current Behavior and Goal), Behavior Change Technique 3 Message (Feedback on Outcome of Behavior), Behavior Change Technique 4 Message (Social Support), Behavior Change Technique 5 Message (Social Comparison), Behavior Change Technique 6 Message (Social Reward), Behavior Change Technique 7 Message (Focus on Past Success)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 39 Years
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 28, 2026, 1:12 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimal Digital Weight Loss Treatment for Rural Individuals

NCT06105957
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Core, Facilitated Weekly Group Sessions, Counselor Crafted Feedback, Individual Coaching Calls, Pre-Scripted Feedback
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
616 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 28, 2026, 1:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Healthy Families Healthy Forces Study

NCT02348853
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Healthy Weight for Living (HWL), Current Best Practice (CBP)
Behavioral
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
308 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2020 · Synced Sep 28, 2026, 1:12 AM EDT
Recruiting Not applicable Interventional

Efficacy of a Telehealth Delivered Group Lifestyle Balance for People Post Stroke (tGLB-CVA)

NCT06569121
View directory record Official record
Conditions
Stroke, Acute, Stroke, Stroke, Cardiovascular, Stroke (CVA) or TIA, Stroke/Brain Attack
Interventions
Group Lifestyle Balance for People Post Stroke (GLB-CVA)
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 85 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 28, 2026, 1:12 AM EDT
Active, not recruiting Not applicable Interventional

Behavioral Weight Loss for Cancer Survivors in Maryland: A Trial With Adaptive Interventions

NCT06463249
View directory record Official record
Conditions
Weight Loss
Interventions
CORE Helpline, Extended Helpline, Enhanced Helpline, Intensive Helpline
Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 28, 2026, 1:12 AM EDT