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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:53 AM EST

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Showing 1–24 of 64 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Weight loss core Clear all

Conditions: Smoking Cessation, Obesity
Interventions: Self-Regulation strategies + large changes (SR), Healthy Lifestyle Education (LE), Smoking Cessation Treatment; Behavioral · Other
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Pediatric Obesity
Interventions: Parents as Coaches, Parent Weight Loss; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 12 Years to 16 Years
Enrollment: 162 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Henrico, Virginia

Conditions: Pediatric Obesity
Interventions: TEENS+Parents as Coaches, TEENS+Parent Weight Loss; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 12 Years to 16 Years
Enrollment: 418 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Henrico, Virginia

Conditions: Stroke, Acute, Stroke, Stroke, Cardiovascular, Stroke (CVA) or TIA, Stroke/Brain Attack
Interventions: Group Lifestyle Balance for People Post Stroke (GLB-CVA); Behavioral
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years to 85 Years
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Obesity
Interventions: Small changes weight loss program; Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Blood Pressure, High Blood Pressure, Dietary Modification, Overweight and Obesity
Interventions: Self-Guided Approach, Dietitian-led Approach; Behavioral
Lead sponsor: Geisinger Clinic; Other
Eligibility: 18 Years and older
Enrollment: 187 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Danville, Pennsylvania • Wilkes-Barre, Pennsylvania

Conditions: Body Weight, Body Weight Changes, Obesity, Overweight and Obesity, Overweight, Behavior, Eating, Physical Inactivity, Chronic Disease, Weight Loss, Weight Reduction
Interventions: Together, Eating and Activity, Matter Plus (TEAM+) Online, Together, Eating and Activity, Matter Plus (TEAM+) In-Person; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 75 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Weight Loss, Diet, Healthy, Cardiovascular Risk Factor
Interventions: Med-South Weight Loss Intervention, WW; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 75 Years
Enrollment: 360 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Obesity
Interventions: Peer-Led Group Lifestyle Balance, Usual Care Services; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 314 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Obesity
Interventions: Behavioral weight loss intervention (Online; Rx Weight Loss), Minority stress intervention, Social support intervention, Negative body image intervention; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Type 2 Diabetes, Pre-Diabetes
Interventions: Men-Tailored DPP (Power-Up); Other
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 18 Years and older · Male only
Enrollment: 301 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Obesity, Dysmobility
Interventions: Multi Modal Balance Training (MMBI), Weight Loss (WL); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 60 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cardiovascular Diseases, Obesity
Interventions: Online Behavioral Weight Loss Program, Physical Activity Intervention, Bite Counter, Virtual Reality, Virtual Meetings; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 21 Years to 75 Years
Enrollment: 198 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Breast Cancer
Interventions: Weight Loss Dietary Pattern; Other
Lead sponsor: Colorado State University; Other
Eligibility: 21 Years and older · Female only
Enrollment: 259 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms, Type 2 Diabetes, PreDiabetes, Insulin Resistance
Interventions: Good Days Ahead (GDA), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications, Active Control; Behavioral · Drug · Other
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Overweight and Obesity, Weight Loss Maintenance, Dietary Habits
Interventions: Weight Loss Maintenance (Control vs. Reverse Diet); Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 21 Years to 70 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Overweight and Obesity
Interventions: Core Behavioral Weight Loss (BWL) intervention, Dyadic Action Planning, Joint Feedback, Autonomy Support Training, Home Environment Modifications; Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years to 75 Years
Enrollment: 762 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Obesity, Overweight, Overweight and Obesity
Interventions: Core Behavioral Weight Loss (BWL) Intervention, Behavior Change Technique 1 Message (Action Planning), Behavior Change Technique 2 Message (Discrepancy between Current Behavior and Goal), Behavior Change Technique 3 Message (Feedback on Outcome of Behavior), Behavior Change Technique 4 Message (Social Support), Behavior Change Technique 5 Message (Social Comparison), Behavior Change Technique 6 Message (Social Reward), Behavior Change Technique 7 Message (Focus on Past Success); Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 39 Years
Enrollment: 255 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Disability Physical, Wheelchair, Obesity; Overweight
Interventions: The Fast In-Bed Tracking System (FIT) Weight Scale, Group Lifestyle Balance Adapted for Individuals with Impaired Mobility (GLB-AIM) intervention; Device · Behavioral
Lead sponsor: Jonathan Pearlman; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Obesity
Interventions: Behavioral Weight Loss Intervention for Young Adults; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 25 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: PreDiabetes
Interventions: Group Lifestyle Balance (GLB), Group Lifestyle Balance Plus (GLB+); Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 21 Years and older
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: PreDiabetes, Adult Children
Interventions: Metformin, Digital Intervention; Drug · Behavioral
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 18 Years to 44 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: PreDiabetes
Interventions: Noom Coach DPP; Behavioral
Lead sponsor: Noom Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 202 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Childhood Obesity
Interventions: In-Person First Session, Second Caregiver, WiFi-enabled Scale, 10 Core Coaching Calls Only; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 8 Years and older
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Search by objective public record fields.

A Multiple Health Behavior Change Intervention for Overweight and Obese Smokers

The Role of Parents in Adolescent Obesity Treatment

Parent Involvement in Adolescent Obesity Treatment

Efficacy of a Telehealth Delivered Group Lifestyle Balance for People Post Stroke (tGLB-CVA)

A Small Changes Weight Loss Program and Message Dissemination Via Facebook in Chicago's West Side

Remote Dietary Counseling to Promote Healthy Diet and Blood Pressure

Online Family Dyadic Skills Training for Black Adults in Behavioral Weight Loss Program

Delicious Eating for Life in Southern Homes

Peer-Led Healthy Lifestyle Program in Supportive Housing

Optimizing an Online Behavioral Weight Loss Intervention and Novel Culturally Tailored Components for Sexual Minority Women

Power-Up: An Effectiveness Trial of the Diabetes Prevention Program

Multimodel Exercise and Weight Loss in Older Obese Veterans With Dysmobility

Creating an Optimized Technology-Based Weight Loss Program for Cardiac Rehabilitation Patients

Diet Composition, Weight Control, and Breast Carcinogenesis

eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk

Feasibility and Preliminary Efficacy of a Reverse Diet as a Novel Weight Loss Maintenance Strategy for Weight-Reduced Adults With Overweight/Obesity

Becoming United in Lifestyle Decisions

Just-in-time Adaptive Intervention Messaging in a Digital Weight Loss Intervention for Young Adults

Fast In-Bed Tracking (FIT) System Lifestyle Intervention is a Clinical Trial of a Bed Scale Device. Overweight Wheelchair Users Will Complete a Weight Loss Program, Half Get Scales at Baseline, Half at Month 6 Those Who Receive the Bed Scales at Baseline Are Expected to Have Increased Weight Loss

Recruiting and Retaining Young Adults in Behavioral Weight Loss Treatment

Augmented Care at Worksite for Diabetes Prevention

An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

Prevention of Diabetes Using Mobile-enabled, Virtual Delivery of the National Diabetes Prevention Program

CHAT at HOME Pilot Study